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2018

Rakha, Emad A., Aleskandarany, Mohammed A., Toss, Michael S., Mongan, Nigel, ElSayed, Maysa E., Green, Andrew R., Ellis, Ian O. and Dalton, Leslie W. (2018) Impact of breast cancer grade discordance on prediction of outcome. Histopathology . ISSN 03090167

Sonbul, Sultan N., Aleskandarany, Mohammed A., Kurozumi, Sasagu, Joseph, Chitra, Toss, Michael S., Diez-Rodriguez, Maria, Nolan, Christopher C., Mukherjee, Abhik, Martin, Stewart, Caldas, Carlos, Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2018) Saccharomyces cerevisiae-like 1 (SEC14L1) is a prognostic factor in breast cancer associated with lymphovascular invasion. Modern Pathology . ISSN 0893-3952

Miligy, Islam, Gorringe, Kylie L., Toss, Michael S., Al-Kawaz, Abdubaqi, Simpson, Peter, Diez-Rogriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Green, Andrew R. and Rakha, Emad (2018) Thioredoxin interacting protein (TXNIP) is an independent risk stratifier for breast ductal carcinoma in situ. Modern Pathology . ISSN 1530-0285

Althobiti, Maryam, Aleskandarany, Mohammed A., Joseph, Chitra, Toss, Michael, Mongan, Nigel, Diez-Rodriguez, Maria, Nolan, Christopher C., Ashankyty, Ibraheem, Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2018) Heterogeneity of Tumour Infiltrating Lymphocytes (TILs) in breast cancer and its prognostic significance. Histopathology . ISSN 0309-0167

Althobiti, Maryam, Aleskandarany, Mohammed A., Joseph, Chitra, Toss, Michael S., Mongan, Nigel P., Diez-Rodriguez, Maria, Nolan, Christopher C., Ashankyty, I., Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2018) Heterogeneity of tumour infiltrating lymphocytes (TILs) in breast cancer and its prognostic significance. Histopathology . ISSN 1365-2559

Shah, Deep, Wyatt, Debra, Baker, Andrew, Simms, Patricia, Peiffer, Daniel S., Fernandez, Michelle L., Rakha, Emad A., Green, Andrew R., Filipovic, Aleksandra, Miele, Lucio and Osipo, Clodia (2018) Inhibition of HER2 enriches for Jagged1-dependent breast cancer stem cells: role for membrane Jagged1. Clinical Cancer Research . ISSN 1557-3265

Kurozumi, Sasagu, Joseph, Chitra, Sonbul, Sultan, Aleskandarany, Mohammed A., Pigera, Marian, Alsaleem, Mansour, Alsaeed, Sami, Kariri, Yousif, Nolan, Christopher C., Diez-Rodriguez, Maria, Johnston, Simon, Mongan, Nigel P., Fujii, Takaaki, Shirabe, Ken, Martin, Stewart G., Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2018) Clinicopathological and prognostic significance of Ras Association and Pleckstrin Homology domains 1 (RAPH1) in breast cancer. Breast Cancer Research and Treatment . ISSN 1573-7217 (In Press)

Kurozumi, Sasagu, Joseph, Chitra, Sonbul, Sultan, Gorringe, Kylie L., Pigera, Marian, Aleskandarany, Mohammed A., Diez-Rodriguez, Maria, Nolan, Christopher C., Fujii, Takaaki, Shirabe, Ken, Kuwano, Hiroyuki, Storr, Sarah, Martin, Stewart G., Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2018) Clinical and biological roles of Kelch-like family member 7 in breast cancer: a marker of poor prognosis. Breast Cancer Research and Treatment, 170 (3). pp. 525-533. ISSN 1573-7217

Ahmad, Narmeen, Ammar, Aula, Storr, Sarah J., Green, Andrew R., Rakha, Emad, Ellis, Ian and Martin, Stewart G. (2018) IL-6 and IL-10 are associated with good prognosis in early stage invasive breast cancer patients. Cancer Immunology, Immunotherapy, 67 (4). pp. 537-549. ISSN 1432-0851

Pu, Xuan, Storr, Sarah J., Ahmad, Narmeen, Rakha, Emad, Green, Andrew R., Ellis, Ian O. and Martin, Stewart G. (2018) High nuclear MSK1 is associated with longer survival in breast cancer patients. Journal of Cancer Research and Clinical Oncology, 144 (3). pp. 509-517. ISSN 1432-1335

Joseph, Chitra, Macnamara, Olivia, Craze, Madeleine, Russell, Roslin, Provenzano, Elena, Nolan, Christopher C., Diez-Rodriguez, Maria, Sonbul, Sultan N., Aleskandarany, Mohammed A., Green, Andrew R., Rakha, Emad A., Ellis, Ian O. and Mukherjee, Abhik (2018) Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes. British Journal of Cancer . ISSN 0007-0920

El Ansari, Rokaya, Craze, Madeleine L., Miligy, Islam, Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad and Green, Andrew R. (2018) The amino acid transporter SLC7A5 confers a poor prognosis in the highly proliferative breast cancer subtypes and is a key therapeutic target in luminal B tumours. Breast Cancer Research, 20 (21). pp. 1-17. ISSN 1465-542X

Toss, Michael S., Miligy, Islam, Al-Kawaz, Abdubaqi, Alsleem, Mansour, Khout, Hazem, Rida, Padmashree C., Aneja, Ritu, Green, Andrew R., Ellis, Ian O. and Rakha, Emad (2018) Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast. Modern Pathology . ISSN 1530-0285

El Ansari, Rokaya, Craze, Madeleine L., Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad A. and Green, Andrew R. (2018) The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes. British Journal of Cancer, 118 . pp. 1115-1122. ISSN 1532-1827

Desmedt, Christine, Salgado, Roberto, Fornili, Marco, Pruneri, Giancarlo, Gert Van den Eynden, Gert, Zoppoli, Gabriele, Rothé, Françoise, Buisseret, Laurence, Garaud, Soizic, Willard-Gallo, Karen, Brown, David, Bareche, Yacine, Rouas, Ghizlane, Galant, Christine, Bertucci, François, Loi, Sherene, Viale, Giuseppe, Di Leo, Angelo, Green, Andrew R., Ellis, Ian O., Rakha, Emad, Larsimont, Denis, Biganzoli, Elia M. and Sotiriou, Christos (2018) Immune infiltration in invasive lobular breast cancer. Journal of the National Cancer Institute . ISSN 1460-2105

Gong, Chun, Man, Ellen P.S., Tsoi, Ho, Lee, Terence K.W., Paul, Lee, Mak, Sai-Ting, Wong, Lai-Shan, Luk, Mei-Yee, Rakha, Emad A., Green, Andrew R., Ellis, Ian O., Lam, Eric W.F., Cheung, Kwok-Leung and Khoo, Ui-Soon (2018) BQ323636.1, a novel splice variant to NCOR2, as a predictor for tamoxifen resistant breast cancer. Clinical Cancer Research . ISSN 1557-3265

Al-Subhi, Nouf, Ali, Reem, Abdel-Fatah, Tarek, Moseley, Paul M., Chan, Stephen Y.T., Green, Andrew R., Ellis, Ian O., Rakha, Emad and Madhusudan, Srinivasan (2018) Targeting ataxia telangiectasia mutated and Rad3 related kinase (ATR) in PTEN deficient breast cancers for personalized therapy. Breast Cancer Research and Treatment . ISSN 1573-7217

2017

Coleman, William B., Syed, Binafsha Manzoor, Morgan, DAL, Setty, Tulassi, Green, Andrew R., Paish, Emma C., Ellis, Ian O. and Cheung, Kwok-Leung (2017) Oestrogen receptor negative early operable primary breast cancer in older women—biological characteristics and long-term clinical outcome. PLoS ONE, 12 (12). e0188528/1-e0188528/12. ISSN 1932-6203

Rakha, Emad A., Miligy, Islam, Gorringe, Kylie L., Toss, Michael S., Green, Andrew R., Fox, Stephen B., Schmitt, Fernando C., Tan, Puay-Hoon, Tse, Gary M., Badve, Sunil, Decker, Thomas, Vincent-Salomon, Anne, Dabbs, David J., Foschini, Maria P., Moreno, Filipa, Wentao, Yang, Geyer, Felipe C., Reis-Filho, Jorge S., Pinder, Sarah E., Lakhani, Sunil R. and Ellis, Ian O. (2017) Invasion in breast lesions: the role of the epithelial-stroma barrier. Histopathology . ISSN 0309-0167

Craze, Madeleine L., Cheung, Hayley, Jewa, Natasha, Coimbra, Nuno D.M., Soria, Daniele, El-Ansari, Rokaya, Aleskandarany, Mohammed A., Cheng, Kiu Wai, Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad and Green, Andrew R. (2017) MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer. British Journal of Cancer . ISSN 1532-1827

Aleskandarany, Mohammed A., Sonbul, Sultan N., Surridge, Rachel, Mukherjee, Abhik, Caldas, Carlos, Diez-Rodriguez, Maria, Ashankyty, I., Albrahim, Khalil I., Elmouna, Ahmed M., Aneja, Ritu, Martin, Stewart G., Ellis, Ian O., Green, Andrew R. and Rakha, Emad A. (2017) Rho-GTPase activating protein 18: a biomarker associated with good prognosis in invasive breast cancer. British Journal of Cancer, 117 . pp. 1176-1184. ISSN 1532-1827

El Ansari, Rokaya, McIntyre, Alan, Craze, Madeleine L., Ellis, Ian O., Rakha, Emad A. and Green, Andrew R. (2017) Altered glutamine metabolism in breast cancer: subtype dependencies and alternative adaptations. Histopathology . ISSN 0309-0167

Muftah, Abir A., Aleskandarany, Mohammed A., Al-kaabi, Methaq M., Sonbul, Sultan N., Diez-Rodriguez, Maria, Nolan, Christopher C., Caldas, Carlos, Ellis, Ian O., Rakha, Emad A. and Green, Andrew R. (2017) Ki67 expression in invasive breast cancer: the use of tissue microarrays compared with whole tissue sections. Breast Cancer Research and Treatment, 164 (2). pp. 341-348. ISSN 1573-7217

Chrysanthou, Eleni, Gorringe, Kylie L., Joseph, Chitra, Craze, Madeleine L., Nolan, Christopher C., Diez-Rodriguez, Maria, Green, Andrew R., Rakha, Emad A., Ellis, Ian O. and Mukherjee, Abhik (2017) Phenotypic characterization of breast cancer: the role of CDC42. Breast Cancer Research and Treatment, 164 (2). pp. 317-325. ISSN 1573-7217

Joseph, C., Craze, Madeleine L., Nolan, C.C., Diez-Rodriguez, Maria, Green, Andrew R., Rakha, Emad, Ellis, Ian O. and Mukherjee, A. (2017) FOXP1 expression correlates with better prognosis in invasive breast cancer including the ER-positive luminal subtype. In: Belfast Pathology 2017: 10th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 20-23 June 2017, Belfast , United Kingdom.

Green, Andrew R., Aleskandarany, Mohammed A., Ali, Reem, Hodgson, Eleanor Grace, Atabani, Suha, De Souza, Karen, Ellis, Ian O., Rakha, Emad and Madhusudan, Srinivasan (2017) Clinical impact of tumor DNA repair expression and T-cell infiltration in breast cancers. Cancer Immunology Research, 5 (4). pp. 292-299. ISSN 2326-6074

Sonbul, Sultan N., Gorringe, Kylie L., Aleskandarany, Mohammed A., Mukherjee, Abhik, Green, Andrew R., Ellis, Ian O. and Rakha, Emad A. (2017) Chemokine (C-C motif) receptor 7 (CCR7) associates with the tumour immune microenvironment but not progression in invasive breast carcinoma. Journal of Pathology, 3 (2). pp. 105-114. ISSN 1096-9896

Arora, Arvind, Parvathaneni, Swetha, Aleskandarany, Mohammed A., Agarwal, Devika, Ali, Reem, Abdel-Fatah, Tarek, Green, Andrew R., Ball, Graham R., Rakha, Emad A., Ellis, Ian O., Sharma, Sudha and Madhusudan, Srinivasan (2017) Clinicopathological and functional significance of RECQL1 helicase in sporadic breast cancers. Molecular Cancer Therapeutics, 16 (1). pp. 239-250. ISSN 1538-8514

2016

Xuan, Pu, Storr, Sarah J., Zhang, Yimin, Rakha, Emad, Green, Andrew R., Ellis, Ian O. and Martin, Stewart G. (2016) Caspase-3 and caspase-8 expression in breast cancer: caspase-3 is associated with survival. Apoptosis . pp. 1-12. ISSN 1573-675X

Ahmad, Dena Akram Jerjees, Negm, Ola H., Layth Alabdullah, M., Mirza, Sameer, Hamed, Mohamed R., Band, Vimla, Green, Andrew R., Ellis, Ian O. and Rakha, Emad (2016) Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers. Breast Cancer Research and Treatment, 159 (3). pp. 457-467. ISSN 1573-7217

Alshareeda, Alaa, Negm, Ola H., Aleskandarany, Mohammed A., Green, Andrew R., Nolan, Christopher, Tighe, Patrick J., Madhusudan, Srinivasan, Ellis, Ian O. and Rakha, Emad (2016) Clinical and biological significance of RAD51 expression in breast cancer: a key DNA damage response protein. Breast Cancer Research and Treatment, 159 (1). pp. 41-53. ISSN 1573-7217

Aleskandarany, Mohammed A., Green, Andrew R., Ashankyty, I., Elmouna, A., Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O. and Rakha, Emad (2016) Impact of intratumoural heterogeneity on the assessment of Ki67 expression in breast cancer. Breast Cancer Research and Treatment, 158 (2). pp. 287-295. ISSN 1573-7217

Abdel-Fatah, Tarek M.A., Agarwal, Devika, Liu, Dong-Xu, Russell, Roslin, Rueda, Oscar M., Liu, Karen, Xu, Bing, Moseley, Paul M., Green, Andrew R., Pockley, Alan G., Rees, Robert C., Caldas, Carlos, Ellis, Ian O., Ball, Graham R. and Chan, Stephen Y.T. (2016) SPAG5 as a prognostic biomarker and chemotherapy sensitivity predictor in breast cancer: a retrospective, integrated genomic, transcriptomic, and protein analysis. Lancet Oncology, 17 (7). pp. 1004-1018. ISSN 1474-5488

Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M., Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A., Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W.Y., Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F., Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R., McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R., Ellis, Ian O., Purushotham, Arnie, Pinder, Sarah E., Børresen-Dale, Anne-Lise, Earl, Helena M., Pharoah, Paul D., Ross, Mark T., Aparicio, Samuel and Caldas, Carlos (2016) The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes. Nature Communications, 7 . 11479/1-11479/15. ISSN 2041-1723

Green, Andrew R., Soria, Daniele, Powe, Desmond G., Nolan, Christopher C., Aleskandarany, Mohammed A., Szász, M.A., Tőkés, A.M., Ball, G.R., Garibaldi, Jonathan M., Rakha, Emad, Kulka, J. and Ellis, Ian O. (2016) Nottingham prognostic index plus (NPI+) predicts risk of distant metastases in primary breast cancer. Breast Cancer Research and Treatment, 157 (1). pp. 65-75. ISSN 0167-6806

Arora, Arvind, Agarwal, Devika, Abdel-Fatah, Tarek M.A., Lu, Huiming, Croteau, Deborah L., Moseley, Paul, Aleskandarany, Mohammed A., Green, Andrew R., Ball, Graham, Rakha, Emad A., Chan, Stephen Y.T., Ellis, Ian O., Wang, Lisa L., Zhao, Yongliang, Balajee, Adayabalam S., Bohr, Vilhelm A. and Madhusudan, Srinivasan (2016) RECQL4 helicase has oncogenic potential in sporadic breast cancers. Journal of Pathology, 238 (4). pp. 495-501. ISSN 1096-9896

Green, Andrew R., Soria, Daniele, Stephen, Jacquelin, Powe, Desmond G., Nolan, Christopher C., Kunkler, Ian, Thomas, Jeremy, Kerr, Gillian R., Jack, Wilma, Cameron, David, Piper, Tammy, Ball, Graham R., Garibaldi, Jonathan M., Rakha, Emad, Bartlett, John M.S. and Ellis, Ian O. (2016) Nottingham Prognostic Index Plus: validation of a clinical decision making tool in breast cancer in an independent series. Journal of Pathology: Clinical Research, 2 . pp. 32-40. ISSN 2056-4538

Negm, Ola H., Muftah, Abir A., Aleskandarany, Mohammed A., Hamed, Mohamed R., Ahmad, Dena A.J., Nolan, Christopher C., Diez-Rodriguez, Maria, Tighe, Patrick J., Ellis, Ian O., Rakha, Emad A. and Green, Andrew R. (2016) Clinical utility of reverse phase protein array for molecular classification of breast cancer. Breast Cancer Research and Treatment, 155 (1). pp. 25-35. ISSN 1573-7217

2015

Arora, Arvind, Abdel-Fatah, Tarek, Agarwal, Devika, Doherty, Rachel, Moseley, Paul M., Aleskandarany, Mohammed A., Green, Andrew R., Ball, Graham, Alshareeda, Alaa, Rakha, Emad, Chan, Stephen Y.T., Ellis, Ian O. and Madhusudan, Srinivasan (2015) Transcriptomic and protein expression analysis reveals clinicopathological significance of bloom syndrome helicase (BLM) in breast cancer. Molecular Cancer Therapeutics, 14 (4). pp. 1057-1065. ISSN 1538-8514

2014

Rakha, Emad, Soria, Daniele, Green, Andrew R., Lemetre, Christophe, Powe, Desmond G., Nolan, Christopher C., Garibaldi, Jonathan M., Ball, Graham and Ellis, Ian O. (2014) Nottingham Prognostic Index Plus (NPI+): a modern clinical decision making tool in breast cancer. British Journal of Cancer, 110 (7). pp. 1688-1697. ISSN 0007-0920

2013

Soria, Daniele, Garibaldi, Jonathan M., Green, Andrew R., Powe, Desmond G., Nolan, Christopher C., Lemetre, Christophe, Ball, Graham R. and Ellis, Ian O. (2013) A quantifier-based fuzzy classification system for breast cancer patients. Artificial Intelligence in Medicine, 58 (3). pp. 175-184. ISSN 0933-3657

2010

Soria, Daniele, Garibaldi, Jonathan M., Ambrogi, Federico, Green, Andrew R., Powe, Des, Rakha, Emad, Douglas Macmillan, R., Blamey, Roger W., Ball, Graham, Lisboa, Paulo J.G., Etchells, Terence A., Boracchi, Patrizia, Biganzoli, Elia M. and Ellis, Ian O. (2010) A methodology to identify consensus classes from clustering algorithms applied to immunohistochemical data from breast cancer patients. Computers in biology and medicine, 40 (3). pp. 318-330. ISSN 0010-4825