MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancerTools Craze, Madeleine L. and Cheung, Hayley and Jewa, Natasha and Coimbra, Nuno D.M. and Soria, Daniele and El-Ansari, Rokaya and Aleskandarany, Mohammed A. and Cheng, Kiu Wai and Diez-Rodriguez, Maria and Nolan, Christopher C. and Ellis, Ian O. and Rakha, Emad and Green, Andrew R. (2017) MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer. British Journal of Cancer . ISSN 1532-1827
Official URL: https://www.nature.com/articles/bjc2017387
AbstractBackground: Altered cellular metabolism is a hallmark of cancer and some are reliant on Glutamine for sustained proliferation and survival. We hypothesise that the Glutamine-Proline regulatory axis has a key role in Breast cancer (BC) in the highly proliferative classes.
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