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2018

Styliari, Ioanna D., Conte, Claudia, Pearce, Amanda K., Hüsler, Amanda, Cavanagh, Robert J., Limo, Marion J., Gordhan, Dipak, Nieto-Orellana, Alejandro, Suksiriworapong, Jiraphong, Couturaud, Benoit, Williams, Phil, Hook, Andrew L., Alexander, Morgan R., Garnett, Martin C., Alexander, Cameron, Burley, Jonathan C. and Taresco, Vincenzo (2018) High-throughput miniaturized screening of nanoparticle formation via inkjet printing. Macromolecular Materials and Engineering, 303 (8). ISSN 1439-2054

Donaldson, Amy R., Tanase, Constantin, Awuah, Dennis, Vasanthi, Vasanthi Bathri Narayanan, Hall, Laurence, Nikkhah, Mehdi, Khademhosseini, Ali, Rose, Felicity, Alexander, Cameron and Ghaemmaghami, Amir M. (2018) Photocrosslinkable gelatin hydrogels modulate the production of the major pro-inflammatory cytokine, TNF-α, by human mononuclear cells. Frontiers in Bioengineering and Biotechnology . ISSN 2296-4185 (In Press)

Alazzo, Ali, Lovato, Tatiana, Collins, Hilary M., Taresco, Vincenzo, Stolnik, Snjezana, Soliman, Mahmoud E., Spriggs, Keith and Alexander, Cameron (2018) Structural variations in hyperbranched polymers prepared via thermal polycondensation of lysine and histidine and their effects on DNA delivery. Journal of Interdisciplinary Nanomedicine, 3 (2). pp. 38-54. ISSN 2058-3273

Sasso, Luana, Purdie, Laura, Grabowska, Anna M., Jones, Arwyn Tomos and Alexander, Cameron (2018) Time and cell-dependent effects of endocytosis inhibitors on the internalization of biomolecule markers and nanomaterials. Journal of Interdisciplinary Nanomedicine, 3 (2). pp. 67-81. ISSN 2058-3273

Taresco, Vincenzo, Alexander, Cameron, Singh, Nishant and Pearce, Amanda K. (2018) Stimuli-responsive prodrug chemistries for drug delivery. Advanced Therapeutics . p. 1800030. ISSN 2366-3987

Monaghan, Tanya M., Braim, Shwana, Spiewak, Klaudyna, Brindell, Malgorzata and Alexander, Cameron (2018) Novel lactoferrin-loaded alginate microbeads display anti-Clostridium difficile defence properties. Gut, 67 (Supp 1). A194-A195. ISSN 1468-3288

Oelmann, Stefan, Travanut, Alessandra, Barther, Dennis, Romero, Manuel, Howdle, Steven M., Alexander, Cameron and Meier, Michael A.R. (2018) Biocompatible unimolecular micelles obtained via the Passerini reaction as versatile nanocarriers for potential medical applications. Biomacromolecules . ISSN 1526-4602

Lovato, Tatiana, Taresco, Vincenzo, Alazzo, Ali, Sansone, Catarina, Stolnik, Snjezana, Alexander, Cameron and Conte, Claudia (2018) Rapid formulation of redox-responsive oligo-β-aminoester polyplexes with siRNA via jet printing. Journal of Materials Chemistry B . ISSN 2050-7518 (In Press)

Soliman, Mahmoud E., Elmowafy, Enas, Casettari, Luca and Alexander, Cameron (2018) Star-shaped poly(oligoethylene glycol) copolymer-based gels: thermo-responsive behaviour and bioapplicability for risedronate intranasal delivery. International Journal of Pharmaceutics, 543 (1-2). pp. 224-233. ISSN 1873-3476

Conte, Claudia, Mastrotto, Francesca, Taresco, Vincenzo, Tchoryk, Aleksandra, Quaglia, Fabiana, Stolnik, Snjezana and Alexander, Cameron (2018) Enhanced uptake in 2D- and 3D- lung cancer cell models of redox responsive PEGylated nanoparticles with sensitivity to reducing extra-and intracellular environments. Journal of Controlled Release . ISSN 1873-4995 (In Press)

Sayers, Edward, Magnusson, Johannes Pall, Moody, Paul, Mastrotto, Francesca, Conte, Claudia, Brazzale, Chiara, Borri, Paola, Caliceti, Paolo, Watson, Peter, Mantovani, Giuseppe, Aylott, Jonathan W., Salmaso, Stefano, Jones, Arwyn T. and Alexander, Cameron (2018) Switching of macromolecular ligand display by thermoresponsive polymers mediates endocytosis of multi-conjugate nanoparticles. Bioconjugate Chemistry . ISSN 1520-4812

Purdie, Laura, Alexander, Cameron, Spain, Sebastian G. and Magnusson, Johannes P. (2018) Alkyl-modified oligonucleotides as intercalating vehicles for doxorubicin uptake via albumin binding. Molecular Pharmaceutics, 15 (2). pp. 437-446. ISSN 1543-8392

Sanna, Monica, Sicilia, Giovanna, Alazzo, Ali, Singh, Nishant, Musumeci, Francesca, Schenone, Silvia, Spriggs, Keith, Burley, Jonathan C., Garnett, Martin, Taresco, Vincenzo and Alexander, Cameron (2018) Water solubility enhancement of pyrazolo[3,4-d]pyrimidine derivatives via miniaturized polymer-drug microarrays. ACS Medicinal Chemistry Letters, 9 (3). pp. 193-197. ISSN 1948-5875

Louzao, Iria, Koch, Britta, Taresco, Vincenzo, Ruiz Cantu, Laura, Irvine, Derek J., Roberts, Clive J., Tuck, Christopher J., Alexander, Cameron, Hague, Richard J.M., Wildman, Ricky D. and Alexander, Morgan R. (2018) Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery. ACS Applied Materials & Interfaces, 10 (8). pp. 6841-6848. ISSN 1944-8244

Xue, Xuan, Thiagarajan, Lalitha, Dixon, James E., Saunders, Brian R, Shakesheff, Kevin M. and Alexander, Cameron (2018) Post-modified polypeptides with UCST-type behavior for control of cell attachment in physiological conditions. Materials, 11 (1). 95/1-95/17. ISSN 1996-1944

2017

Foralosso, Ruggero, Moir, Lee, Mastrotto, Francesca, Sasso, Luana, Tchoryk, Aleksandra, Abouselo, Amjad, Grabowska, Anna M., Ashford, Marianne B., Aylott, Jonathan W., Gellert, Paul R., Spain, Sebastian G. and Alexander, Cameron (2017) Control of aggregation temperatures in mixed and blended cytocompatible thermoresponsive block co-polymer nanoparticles. Soft Matter, 40 (13). pp. 7441-7452. ISSN 1744-6848

Ruiter, Floor Agnes Andrea, Alexander, Cameron, Rose, Felicity R.A.J. and Segal, Joel (2017) A design of experiments (DoE) approach to identify the influencing parameters that determine poly-D,L-lactic acid (PDLLA) electrospun scaffold morphologies. Biomedical Materials, 12 (5). 055009/1-055009/11. ISSN 1748-605X

Pearce, Amanda K., Travanut, Alessandra, Couturaud, Benoit, Taresco, Vincenzo, Howdle, Steven M., Alexander, Morgan R. and Alexander, Cameron (2017) Versatile routes to functional RAFT chain transfer agents through the Passerini multicomponent reaction. ACS Macro Letters, 6 (7). pp. 781-785. ISSN 2161-1653

Brazzale, C., Mastrotto, Francesca, Moody, P., Watson, P.D., Balasso, A., Malfanti, A., Mantovani, Giuseppe, Caliceti, Paolo, Alexander, Cameron, Jones, A.T. and Salmaso, Stefano (2017) Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells. Nanoscale, 9 (31). pp. 11137-11147. ISSN 2040-3372

Xue, Xuan, Thiagarajan, Lalitha, Braim, Shwana, Saunders, Brian R., Shakesheff, Kevin M. and Alexander, Cameron (2017) Upper critical solution temperature thermo-responsive polymer brushes and a mechanism for controlled cell attachment. Journal of Materials Chemistry B, 5 (25). pp. 4926-4933. ISSN 2050-750X

Magennis, Eugene Peter, Francini, Nora, Mastrotto, Francesca, Catania, Rosa, Redhead, Martin, Fernandez-Trillo, Francisco, Bradshaw, David, Churchley, David, Winzer, Klaus, Alexander, Cameron and Mantovani, Giuseppe (2017) Polymers for binding of the gram-positive oral pathogen Streptococcus mutans. PLoS ONE, 12 (7). e018008/1-e018008/23. ISSN 1932-6203

Taresco, Vincenzo, Louzao, Iria, Scurr, David J., Turpin, Eleanor R., Laughton, Charles A., Alexander, Cameron, Burley, Jonathan C. and Garnett, Martin (2017) Rapid nano-gram scale screening method of micro-arrays to evaluate drug-polymer blends using high-throughput printing technology. Molecular Pharmaceutics, 14 (6). pp. 2079-2087. ISSN 1543-8384

Blanco-Fernandez, B., Concheiro, A., Makwana, H., Fernandez-Trillo, Francisco, Alexander, Cameron and Alvarez-Lorenzo, C. (2017) Dually sensitive dextran-based micelles for methotrexate delivery. RSC Advances, 7 (24). pp. 14448-14460. ISSN 2046-2069

Gulfam, Muhammad, Matini, Teresa, Monteiro, Patrícia F., Riva, Raphaël, Collins, Hilary, Spriggs, Keith, Howdle, Steven M., Jérôme, Christine and Alexander, Cameron (2017) Bioreducible cross-linked core polymer micelles enhance in vitro activity of methotrexate in breast cancer cells. Biomaterials Science, 5 . pp. 532-550. ISSN 2047-4830

England, Richard M., Hare, Jennifer I., Barnes, Jennifer, Wilson, Joanne, Smith, Aaron, Strittmatter, Nicole, Kemmitt, Paul D., Waring, Michael J., Barry, Simon T., Alexander, Cameron and Ashford, Marianne B. (2017) Tumour regression and improved gastrointestinal tolerability from controlled release of SN-38 from novel polyoxazoline-modified dendrimers. Journal of Controlled Release, 247 . pp. 73-85. ISSN 1873-4995

2016

Kakde, Deepak, Powell, Leagh G., Bansal, Kuldeep K., Howdle, Steve, Irvine, Derek, Mantovani, Giuseppe, Millar, Gavin, Dailey, Lea Ann, Stone, Vicki, Johnston, Helinor J. and Alexander, Cameron (2016) Synthesis, characterization and evaluation of in vitro toxicity in hepatocytes of linear polyesters with varied aromatic and aliphatic co-monomers. Journal of Controlled Release, 244 (B). pp. 214-228. ISSN 1873-4995

Taresco, Vincenzo, Suksiriworapong, Jiraphong, Styliari, Ioanna D., Argent, Richard H., Swainson, Sadie M.E., Booth, Jonathan, Turpin, Eleanor R., Laughton, Charles A., Burley, Jonathan C., Alexander, Cameron and Garnett, Martin C. (2016) New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications. RSC Advances, 6 (111). pp. 109401-109405. ISSN 2046-2069

Taresco, Vincenzo, Suksiriworapong, Jiraphong, Styliari, Ioanna D., Argent, Richard H., Swainson, Sadie M.E., Booth, Jonathan, Turpin, Eleanor R., Laughton, Charles A., Burley, Jonathan C., Alexander, Cameron and Garnett, Martin C. (2016) New N-acyl amino acid-functionalized biodegradable polyesters for pharmaceutical and biomedical applications. RSC Advances, 6 . pp. 109401-109405. ISSN 2046-2069

Taresco, Vincenzo, Suksiriworapong, Jiraphong, Creasey, Rhiannon, Burley, Jonathan C., Mantovani, Giuseppe, Alexander, Cameron and Garnett, Martin (2016) Properties of acyl modified poly(glycerol-adipate) comb-like polymers and their self-assembly into nanoparticles. Journal of Polymer Science Part A: Polymer Chemistry, 54 (20). pp. 3267-3278. ISSN 1099-0518

Kakde, Deepak, Taresco, Vincenzo, Bansal, Kuldeep Kumar, Magennis, E. Peter, Howdle, Steven M., Mantovani, Giuseppe, Irvine, Derek J. and Alexander, Cameron (2016) Amphiphilic block copolymers from a renewable Ɛ-decalactone monomer: prediction and characterization of micellar core effects on drug encapsulation and release. Journal of Materials Chemistry B, 44 . pp. 7119-7129. ISSN 2050-750X

Mastrotto, Francesca, Breen, Alastair, Sicilia, Giovanna, Johnstone, Alexander D., Marsh, Georgina E., Grainger-Boultby, Christine, Russell, Noah A., Alexander, Cameron and Mantovani, Giuseppe (2016) One-pot RAFT and fast polymersomes assembly: a ‘beeline’ from monomers to drug-loaded nanovectors. Polymer Chemistry . ISSN 1759-9962

Mastrotto, Francesca, Breen, A. F., Sicilia, G., Murdan, S., Johnstone, Alexander D., Marsh, Georgina E., Grainger-Boultby, Christine, Russell, Noah A., Alexander, Cameron and Mantovani, Giuseppe (2016) One-pot RAFT and fast polymersomes assembly: a ‘beeline’ from monomers to drug-loaded nanovectors. Polymer Chemistry . ISSN 1759-9962

Leire, Emma, Amaral, Sandra P., Louzao, Iria, Winzer, Klaus, Alexander, Cameron, Fernandez-Megia, Eduardo and Fernandez-Trillo, Francisco (2016) Dendrimer mediated clustering of bacteria: improved aggregation and evaluation of bacterial response and viability. Biomaterials Science, 4 (6). pp. 998-1006. ISSN 2047-4830

Purdie, Laura, Alexander, Cameron, Spain, Sebastian G. and Magnusson, Johannes P. (2016) Influence of polymer size on uptake and cytotoxicity of doxorubicin-loaded DNA–PEG conjugates. Bioconjugate Chemistry, 27 (5). pp. 1244-1252. ISSN 1520-4812

Taresco, Vincenzo, Creasey, Rhiannon, Kennon, J., Mantovani, Giuseppe, Alexander, Cameron, Burley, Jonathan C. and Garnett, Martin C. (2016) Variation in structure and properties of poly(glycerol adipate) via control of chain branching during enzymatic synthesis. Polymer, 89 . pp. 41-69. ISSN 0032-3861

Sicilia, Giovanna, Davis, Adrienne L., Spain, Sebastian G., Magnusson, Johannes P., Boase, Nathan R. B., Thurecht, Kristofer J. and Alexander, Cameron (2016) Synthesis of19F nucleic acid–polymer conjugates as real-time MRI probes of biorecognition. Polymer Chemistry, 7 (12). pp. 2180-2191. ISSN 1759-9962

Braim, S. A., Shakesheff, Kevin M., Saunders, Brian R and Alexander, Cameron (2016) Thermoresponsive magnetic colloidal gels via surface-initiated polymerisation from functional microparticles. Journal of Materials Chemistry B, 4 (5). pp. 962-972. ISSN 2050-750X

Sicilia, Giovanna, Davis, Adrienne L., Spain, Sebastian G., Magnusson, Johannes P., Boase, Nathan R.B., Thurecht, Kristofer J. and Alexander, Cameron (2016) Synthesis of 19F nucleic acid–polymer conjugates as real-time MRI probes of biorecognition. Polymer Chemistry, 7 (12). pp. 2180-2191. ISSN 1759-9962

2015

Grabowska, Anna M., Kircheis, Ralf, Kumari, Rajendra, Clarke, Philip, McKenzie, Andrew, Hughes, Jaime, Mayne, Cerys, Desai, Arpan, Sasso, Luana, Watson, Susan A. and Alexander, Cameron (2015) Systemic in vivo delivery of siRNA to tumours using combination of polyethyleneimine and transferrin–polyethyleneimine conjugates. Biomaterials Science, 3 (11). pp. 1439-1448. ISSN 2047-4830

Malakooti, Negin, Alexander, Cameron and Alvarez-Lorenzo, Carmen (2015) Imprinted contact lenses for sustained release of polymyxin B and related antimicrobial peptides. Journal of Pharmaceutical Sciences, 104 (10). pp. 3386-3394. ISSN 1520-6017

Bansal, Kuldeep K., Kakde, Deepak, Purdie, Laura, Irvine, Derek J., Howdle, Steven M., Mantovani, Giuseppe and Alexander, Cameron (2015) New biomaterials from renewable resources – amphiphilic block copolymers from δ-decalactone. Polymer Chemistry, 6 (40). pp. 7196-7210. ISSN 1759-9962

Louzao, Iria, Sui, Cheng, Winzer, Klaus, Fernandez-Trillo, Francisco and Alexander, Cameron (2015) Cationic polymer mediated bacterial clustering: cell-adhesive properties of homo- and copolymers. European Journal of Pharmaceutics and Biopharmaceutics, 95 . pp. 47-62. ISSN 1873-3441

Gallon, Elena, Matini, Teresa, Sasso, Luana, Mantovani, Giuseppe, Armiñan de Benito, Ana, Sanchis, Joaquin, Caliceti, Paolo, Alexander, Cameron, Vicent, Maria J. and Salmaso, Stefano (2015) Triblock copolymer nanovesicles for pH-responsive targeted delivery and controlled release of siRNA to cancer cells. Biomacromolecules, 16 (7). pp. 1924-1937. ISSN 1526-4602

Mackenzie, Robert, Booth, Jonathan, Alexander, Cameron, Garnett, Martin and Laughton, Charles A. (2015) Multiscale modelling of drug-polymer nanoparticle assembly identifies parameters influencing drug encapsulation efficiency. Journal of Chemical Theory and Computation, 11 (6). pp. 2705-2713. ISSN 1549-9618

Francini, Nora, Purdie, Laura, Alexander, Cameron, Mantovani, Giuseppe and Spain, Sebastian G. (2015) Multifunctional poly[N-(2-hydroxypropyl)methacrylamide] copolymers via postpolymerization modification and sequential thiol–ene chemistry. Macromolecules, 48 (9). pp. 2857-2863. ISSN 1520-5835

Saeed, Aram Omer, Francini, Nora, White, Lisa, Dixon, James E., Gould, Toby W.A., Rashidi, Hassan, Cheikh Al Ghanami, Racha, Hruschka, Veronika, Redl, Heinz, Saunders, Brian R, Alexander, Cameron and Shakesheff, Kevin (2015) A thermoresponsive and magnetic colloid for 3D cell expansion and reconfiguration. Advanced Materials, 27 . pp. 662-668. ISSN 0935-9648

2014

Magennis, Eugene Peter, Fernandez-Trillo, Francisco, Sui, Cheng, Spain, Sebastian G., Bradshaw, David, Churchley, David, Mantovani, Giuseppe, Winzer, Klaus and Alexander, Cameron (2014) Bacteria-instructed synthesis of polymers for self-selective microbial binding and labelling. Nature Materials, 13 (7). pp. 748-755. ISSN 1476-1122

2013

Lui, Leong T., Xue, Xuan, Sui, Cheng, Brown, Alan, Pritchard, David I., Halliday, Nigel, Winzer, Klaus, Howdle, Stephen M., Fernandez-Trillo, Francisco, Krasnogor, Natalio and Alexander, Cameron (2013) Bacteria clustering by polymers induces the expression of quorum sense controlled phenotypes. Nature Chemistry, 5 (12). pp. 1058-1065. ISSN 1755-4349

Fowler, Robyn, Vllasaliu, Driton, Falcone, Franco H., Garnett, Martin, Smith, Bryan, Horsley, Helen, Alexander, Cameron and Stolnik, Snow (2013) Uptake and transport of B12-conjugated nanoparticles in airway epithelium. Journal of Controlled Release, 172 (1). pp. 374-381. ISSN 1873-4995

Fowler, Robyn, Vllasaliu, Driton, Trillo, Francisco Fernández, Garnett, Martin, Alexander, Cameron, Horsley, Helen, Smith, Bryan, Whitcombe, Ian, Eaton, Mike and Stolnik, Snow (2013) Nanoparticle transport in epithelial cells: pathway switching through bioconjugation. Small, 9 (19). pp. 3282-3294. ISSN 1613-6829