Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report

Wu, Chun-Yang, Yu, Xiao-Pin, Ma, Ada Hoi Yan, Wang, Li-Ping, Yang, Nai-Bin, Li, Guo-Xiang, Shi, Jie-Jun and Qian, Guo-Qing (2020) Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report. Journal of International Medical Research, 48 (9). 030006052095225. ISSN 0300-0605

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Abstract

Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, an epidemic has spread rapidly worldwide. COVID-19 is caused by the highly infectious severe acute respiratory syndrome coronavirus-2. A 42-year-old woman presented to hospital who was suffering from epigastric discomfort and dyspepsia for the past 5 days. Before the onset of symptoms, she was healthy, and had no travel history to Wuhan or contact with laboratory-confirmed COVID-19 cases. An examination showed chronic superficial gastritis with erosion and esophagitis. Enhanced magnetic resonance imaging of the abdomen showed a lesion in the right lower lobe of the lungs. Chest computed tomography showed multiple ground-glass opacity in the lungs. Reverse transcription-polymerase chain reaction was negative for severe acute respiratory syndrome coronavirus-2. There was no improvement after antibiotic treatment. Polymerase chain reaction performed 2 days later was positive and she was diagnosed with COVID-19. After several days of antiviral and symptomatic treatments, her symptoms improved and she was discharged. None of the medical staff were infected. Clinical manifestations of COVID-19 are nonspecific, making differentiating it from other diseases difficult. This case shows the sequence in which symptoms developed in a patient with COVID-19 with gastrointestinal symptoms as initial manifestations.

Item Type: Article
Additional Information: This is Gold OA
Keywords: COVID-19; severe acute respiratory syndrome coronavirus-2; gastrointestinal symptoms; angiotensin-converting enzyme 2; lungs; dyspepsia; reverse transcriptase-polymerase chain reaction
Schools/Departments: University of Nottingham Ningbo China > Faculty of Business > Nottingham University Business School China
Identification Number: 10.1177/0300060520952256
Depositing User: QIU, Lulu
Date Deposited: 28 Dec 2020 08:27
Last Modified: 28 Dec 2020 08:27
URI: https://eprints.nottingham.ac.uk/id/eprint/64179

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