Topographical and chemical effects of electrochemically assisted deposited hydroxyapatite coatings on osteoblast-like cellsTools Pegg, Elise C., Matboli, Faisal, Marriott, Tim, Khan, Imran and Scotchford, Colin (2014) Topographical and chemical effects of electrochemically assisted deposited hydroxyapatite coatings on osteoblast-like cells. Journal of Biomaterials Applications, 28 (6). pp. 946-953. ISSN 1530-8022 Full text not available from this repository.
Official URL: http://journals.sagepub.com/doi/10.1177/0885328213487410
AbstractA recently commercialised hydroxyapatite electrochemically assisted chemical deposition technique (BoneMaster) has been shown to induce increased bone apposition; whether this response is caused by the surface topography or chemistry is unknown. An in-vitro examination using human osteoblast-like cells was performed on a series of BoneMaster-coated surfaces. The chemistry was separated from the topography using a thin gold coating; Thermanox coverslips were used as a control. BoneMaster surfaces showed significantly greater alkaline phosphatase activity and osteocalcin production compared with controls; however, no difference was found between the gold-coated and uncoated BoneMaster samples, indicating topography is the main contributing factor.
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