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Tsoleridis, Theocharis, Onianwa, Okechukwu, Horncastle, Emma, Dayman, Emma, Zhu, Miaoran, Danjittrong, Taechasit, Wachtl, Marta, Behnke, Jerzy M., Chapman, Sarah, Strong, Victoria, Dodds, Phillipa, Tarlinton, Rachael E., Ball, Jonathan K. and McClure, Patrick (2016) Discovery of novel alphacoronaviruses in European rodents and shrews. Viruses, 8 (3). 84/1-84/9. ISSN 1999-4915

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Abstract

Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex araneus and Myodes glareolus. These, together with the recently described Lucheng virus found in China, form a distinct rodent/shrew-specific clade within the coronavirus phylogeny. Across a highly conserved region of the viral polymerase gene, the new members of this clade were up to 22% dissimilar at the nucleotide level to the previously described Lucheng virus. As such they might represent distinct species of alphacoronaviruses. These data greatly extend our knowledge of wildlife reservoirs of alphacoronaviruses.

Item Type:	Article
Keywords:	coronaviruses, rodents, shrews, alphacoronavirus
Schools/Departments:	University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Life Sciences University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number:	https://doi.org/10.3390/v8030084
Depositing User:	Tarlinton, Dr Rachael
Date Deposited:	21 Mar 2016 09:09
Last Modified:	08 May 2020 10:30
URI:	https://eprints.nottingham.ac.uk/id/eprint/32400

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