The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia

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Driver, Ian, Blockley, Nicholas, Fisher, Joseph, Francis, Susan and Gowland, Penny A. (2010) The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia. NeuroImage, 51 (1). pp. 274-279. ISSN 1053-8119

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Abstract

Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect. In this work BOLD/R2* CVR was investigated by using a device which provided small, repeatable and stable steps in PETCO2, whilst maintaining a steady PETO2 level. Significant CVR was observed in both grey and white matter at both 3 & 7T, whilst an approximately linear relationship found between R2* CVR and field strength has implications for BOLD models and calibration. Grey matter R2* CVR was 0.066±0.004 s-1 mmHg-1 at 3T and 0.141±0.008 s-1mmHg-1 at 7T. White matter R2* CVR was 0.021±0.003 s-1mmHg-1 at 3T and 0.040±0.007 s-1mmHg-1 at 7T.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/706319
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Physics and Astronomy
Identification Number: https://doi.org/10.1016/j.neuroimage.2009.12.113
Related URLs:
URLURL Type
http://dx.doi.org/10.1016/j.neuroimage.2009.12.113Publisher
Depositing User: Driver, Mr Ian
Date Deposited: 17 Jun 2010 16:41
Last Modified: 04 May 2020 16:29
URI: https://eprints.nottingham.ac.uk/id/eprint/1313

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