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2024

Alghamdi, Hajar (2024) On-Demand Dopamine Receptor Activation via Photoresponsive Nanoparticle-Dopamine Conjugates with an Emphasis on Parkinson’s Disease. PhD thesis, University of Nottingham.

Allison, Matthew (2024) α-Amidobenzylboronates and β-Ketobenzylboronates as Inhibitors of Plasma Kallikrein. PhD thesis, University of Nottingham.

Andrea, Bombana (2024) A Minimal Peptide Scaffold for [4Fe-4S]-Cluster Interrogation and Catalysis. PhD thesis, University of Nottingham.

Betts, Hannah (2024) Mechanisms of Replication Protein A-dependent R-loop resolution by the human DNA repair helicase, HelQ. PhD thesis, University of Nottingham.

Chak, Samuel Erwin Seng Chung (2024) The dynamic role of mRNA m6A methylation in Arabidopsis thaliana and Solanum lycopersicum. PhD thesis, University of Nottingham.

Chowdhury, Lamia Noushin Sadeque (2024) Investigating the size-dependent toxicological effects of zinc oxide nanoparticles on Caenorhabditis elegans and the inhibitory potential of Cytochrome P450 isozymes. MPhil thesis, University of Nottingham.

Connolly, Caitlin S (2024) Application of Dynamic Nuclear Polarisation and other advanced Magnetic Resonance methods for studies of Aβ(1-40) interactions with lipids. PhD thesis, University of Nottingham.

Dawson, Owen (2024) From the extracellular matrix to the microprocessor: Investigating the post-transcriptional regulation of miRNA-155 by tenascin-C. PhD thesis, University of Nottingham.

Fiedler, Benjamin (2024) Sugar-coated nanoparticles: Investigating lipid-terminated glycopolymers for targeted nanoparticle delivery of nucleic acids. PhD thesis, University of Nottingham.

Kapp, James (2024) Domain swapping to generate new antibiotic proteins. PhD thesis, University of Nottingham.

Li, Tian-Tian (2024) PHARMACOLOGICAL EVALUATION OF NOVEL COMPOUNDS AS ALZHEIMER’S DISEASE TREATMENT. PhD thesis, University of Nottingham.

Takan, Gokhan (2024) Sugar Coated Formulations. PhD thesis, University of Nottingham.

Tan, Hui Shee (2024) Characterisation of ESBL/AmpC-producing Enterobacteriaceae isolated from three poultry farms in West coast, Peninsular Malaysia. MPhil thesis, University of Nottingham.

2023

Alghamdi, Asmahan (2023) Rab-SPIRE interaction: the molecular mechanism of the interaction between Rab27a and SPIRE1. PhD thesis, University of Nottingham.

Alsolami, Areej (2023) Lipocalin-2 (LCN-2) is a novel myokine that reduces lipid accumulation and induces lipolysis in adipocytes. PhD thesis, University of Nottingham.

Arginbekova, Assel (2023) Investigating association of predisposition genes as a risk of developing multifactorial diseases. PhD thesis, University of Nottingham.

Booth, Thomas (2023) Scalable and continuous production of dehydrated protein microparticles as an alternative to lyophilisation. PhD thesis, University of Nottingham.

Brown, Alexander (2023) Structural studies of FXII and associated proteins. PhD thesis, University of Nottingham.

Brown Coker, Dennon-jay (2023) Investigation of Harmonine inhibition of NMDA receptors. MRes thesis, University of Nottingham.

Carlile, Matthew (2023) APPLICATION OF NANOPORE DATA TO THE PIMMS (Pragmatic Insertional Mutation Mapping System) SEQ PIPELINE. MRes thesis, University of Nottingham.

Chrisp, Ruby (2023) Understanding the role of hepatic Neuronal PAS Domain Protein 2 (NPAS2) in circadian rhythmicity and cognition. PhD thesis, University of Nottingham.

Chun, Taewoo (2023) Hydrodynamic and Microscopic Investigations of Polysaccharides and Glycopeptide Antibiotics of Ophthalmological Importance. PhD thesis, University of Nottingham.

Clarke, Britany (2023) The discovery and characterisation of novel antimicrobial peptides against bacterial pathogens with porcine host specificity. PhD thesis, University of Nottingham.

Cowan, Emma (2023) STRUCTURAL AND BIOPHYSICAL ANALYSIS OF UBE3A AND PARTNER PROTEIN COMPLEXES. PhD thesis, University of Nottingham.

Crosby, Jack (2023) A review of biopolymer-based wood consolidants for archaeological wood preservation. MRes thesis, University of Nottingham.

Dennis, Morgan Jane (2023) Investigating the molecular basis of biased signalling at cannabinoid receptors. MRes thesis, University of Nottingham.

Edwards, Harry (2023) Characterising Host Factors Required for CRISPR Cas Adaptation in Escherichia coli. PhD thesis, University of Nottingham.

Garwood, Genevieve (2023) Time-Resolved Spectroscopic Investigations into Reactions of Transition Metal Complexes. PhD thesis, University of Nottingham.

Gaughan, Samuel J H (2023) Effect of Oriented Electric Fields on Biologically Relevant Iron–Sulfur Clusters and Bioinformatics Investigations of Biotin Synthase. PhD thesis, University of Nottingham.

Giangone, Salvatore (2023) Studies Towards the Total Synthesis of Illicium Derived Neolignans. MRes thesis, University of Nottingham.

Grewcock, Declan (2023) Engineering a Mastoparan Peptide Concatemer Prodrug From CircRNA for Cancer Therapy. PhD thesis, University of Nottingham.

Guwela, Veronica Faith (2023) High zinc wheat for sub-Saharan Africa. PhD thesis, University of Nottingham.

He, Wenshi (2023) Surface Mass Spectrometry for in situ Metabolomic Analysis of Human Brain Tumours. PhD thesis, University of Nottingham.

Ivanov, Maksim G. (2023) Recombinant spidroins from infinite circRNA translation. PhD thesis, University of Nottingham.

Khader, Rasha (2023) Protein Kinase C-Delta C2 Domain Interactions in Breast Cancer. PhD thesis, University of Nottingham.

Krause, Sebastian C. (2023) Unphosphorylated dimers are not required for the assembly of active STAT1 and STAT3 homo-and heterodimers. PhD thesis, University of Nottingham.

Lawrence, Steven (2023) A Potential Effect of Cordycepin on the Feedback between Polyadenylation and PI3K/Akt/mTOR Signalling. PhD thesis, University of Nottingham.

Lee, Adam (2023) Studies of the microbiota and the prebiotic effects of galacto-oligosaccharides in suckling pigs. PhD thesis, University of Nottingham.

Li, Zhiwei (2023) Development of existing and novel tyrosinase inhibitors for skin pigmentation: intradermal delivery, biological evaluation and mechanistic studies. PhD thesis, University of Nottingham.

Liu, Ke (2023) Development of a semi-targeted lipidomic method for clinical applications. PhD thesis, University of Nottingham.

Lloyd, James (2023) Developing Carbene Footprinting Mass Spectrometry to Interrogate Protein-Ligand Interactions. PhD thesis, University of Nottingham.

Loayza, Joanna (2023) Further studies in rat models of neural disinhibition: behavioural, in vivo electrophysiological, and translational imaging studies. PhD thesis, University of Nottingham.

Martin, Athena (2023) MicroRNA Regulation in the Inflammatory Response. PhD thesis, University of Nottingham.

Mayer, Matthias (2023) Analysis of substrate selectivity determinants in Ubiquitin Specific Proteases 11 and 15. PhD thesis, University of Nottingham.

Meeds, Oliver (2023) A review of glycoconjugate vaccines: The current state of the technology, considerations for the future, and the gold standard carrier protein, CRM(197). MRes thesis, University of Nottingham.

Nash, Amy Louise (2023) Use of pectin for the spray delivery of mesenchymal stromal cells for brain injury. PhD thesis, University of Nottingham.

Potts, Jordan Cameron (2023) Light-Induced Cytochrome c Redox Mediated Cell Killing. PhD thesis, University of Nottingham.

Rodrigo, Mahari (2023) Investigating the effects of altered Rad51 expression on the DSB repair pathway choice and the conservation of RecA homologs in Saccharomyces cerevisiae. MRes thesis, University of Nottingham.

Sachan, Isha (2023) Investigating Current Delivery Vehicles for Efficient and Targeted Delivery of Therapeutic RNA and Future Perspectives Part A - Investigating current delivery vehicles for efficient and targeted delivery of therapeutic RNA and future perspectives/ Part B - The development of novel polymeric nanoparticles as efficient non-viral RNA delivery vectors. MRes thesis, University of Nottingham.

Smith, Silvia (2023) Characterisation and Intercellular Mechanistic Analysis of Supramolecular, Cationic, mRNA-Loaded Polyplexes for Efficient Transfection in HEK293T and A549 Cells. MRes thesis, University of Nottingham.

Taylor, Leonard (2023) Defining novel targets of the plant N-degron pathways. PhD thesis, University of Nottingham.

Turnbull, James (2023) Identification of bioactive lipids associated with osteoarthritis pain and pathology through targeted lipidomic analyses. PhD thesis, University of Nottingham.

Tuzer, Cemre (2023) Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor. PhD thesis, University of Nottingham.

Wainwright, Thomas (2023) Exploring the biological functions of vtRNA 1-1. MRes thesis, University of Nottingham.

Wragg, Edward (2023) Cardiovascular responses induced by selective adenosine A2A and A2B receptor agonists. PhD thesis, University of Nottingham.

Zhao, Yi (2023) Investigating Molecular Interactions of Thyroid Hormone and Androgen Receptors. MRes thesis, University of Nottingham.

2022

Adam, Lucy (2022) The effect of mephedrone and caffeine, and the influence of WAY-100635 on c-fos expression in the rat brain. MRes thesis, University of Nottingham.

Bridgen, Alexander John / AJB (2022) Identification and characterisation of fip37-4 suppressor mutants in Arabidopsis thaliana. PhD thesis, University of Nottingham.

Cairns, Ryan (2022) Development of biocatalytic approaches and screening methodology for the synthesis of nitrogen-containing small molecules. PhD thesis, University of Nottingham.

Comeo, Eleonora (2022) Illuminating the life of the adenosine receptors: development and application of subtype-selective fluorescent probes for the study of the human A1 and A2A adenosine receptors in living cells. PhD thesis, University of Nottingham.

Cubbon, Andrew (2022) Investigating a human DNA repair helicase that supports CRISPR editing. PhD thesis, University of Nottingham.

Dean, Holly (2022) Investigation of the effects of VGF overexpression and VGF-derived peptides on lipolysis in 3T3-L1 cells. MRes thesis, University of Nottingham.

Dijon, Nicola C (2022) Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias. PhD thesis, University of Nottingham.

Foggin, Sophie (2022) Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS). PhD thesis, University of Nottingham.

Groothuis, Daphne (2022) Towards safe and stable Clostridium botulinum strains for research and industrial applications. PhD thesis, University of Nottingham.

Guest, Ellen (2022) Molecular simulation of protein-ligand complexes. PhD thesis, University of Nottingham.

Harwood, Clare (2022) The molecular basis of Gs protein efficacy at the b2- adrenoceptor. PhD thesis, University of Nottingham.

Hutchison, Ella (2022) Can an inhibitor of a multidrug pump become a substrate? MRes thesis, University of Nottingham.

Inetianbor, Jonathan (2022) Exploring the metabolic potential of novel marine Actinobacteria. PhD thesis, University of Nottingham.

Machado, Lee (2022) A bioinformatic analysis of the Duchenne muscular dystrophy gene and associated gene variants across human cancers. MRes thesis, University of Nottingham.

Morris, Joseph (2022) Can bioluminescence resonance energy transfer be used to elucidate structural and binding information about the ABCG2 transporter? MRes thesis, University of Nottingham.

Nesheva, Desislava (2022) Examining the mechanism of action of small-molecule negative allosteric modulators of the human chemokine receptor CXCR2. PhD thesis, University of Nottingham.

Nuamah, M.F (2022) The study of troglitazone liver toxicity via in vitro and in silico approaches. PhD thesis, University of Nottingham.

Pitchers, Kieran (2022) Dimerization as a strategy to engineer antimicrobial peptides for application against enteric bacterial pathogens of poultry. PhD thesis, University of Nottingham.

Seys, François M. (2022) Expansion of the genome editing toolbox of Clostridium autoethanogenum. PhD thesis, University of Nottingham.

Smith, Lauren (2022) Establishing and Utilising In Vitro Lung Models to Demonstrate Peptide Mediated Non-Viral Delivery. PhD thesis, University of Nottingham.

Smith, Victoria Emily (2022) Atypical DNA replication in Haloferax volcanii in the absence of replication origins. PhD thesis, University of Nottingham.

Studd, Adam (2022) Probing E-cadherin Targeting Peptides Using Atomic Force Microscopy. PhD thesis, University of Nottingham.

Whittaker, Jack Alexander (2022) Sugar, Soil and Sequencing: Studies in Fusarium venenatum. PhD thesis, University of Nottingham.

Yates, Joshua (2022) Investigating Bdellovibrio predation: novel isolates and bioinformatics studies of predatory enzymes. MRes thesis, University of Nottingham.

Zaidi, Jaffer (2022) Studies towards a biomimetic synthesis of simonol A. MRes thesis, University of Nottingham.

Zubrycka, Agata (2022) Investigation of the biochemistry of post-translational modifications to Group VII ETHYLENE RESPONSE FACTORS. PhD thesis, University of Nottingham.

al-jabiry, asia (2022) The Use of Protein Modification and Ion Mobility-Mass Spectrometry to Probe Protein Structure. PhD thesis, University of Nottingham.

2021

Abo Alard, Akeel (2021) Design, Synthesis and Disposition Studies of New ISRIB Analogues, Targeting eIF2B, as Potential Candidates for enhancing protein synthesis rate. PhD thesis, University of Nottingham.

Abrahams, Abigail Bethany (2021) Deciphering the neural mechanisms of oxytocin’s prosocial and antipsychotic-like effects. PhD thesis, University of Nottingham.

Alamoudi, Abdulmohsin (2021) Targeting the hypoxic expression of epidermal growth factor receptor. PhD thesis, University of Nottingham.

Alhujaili, Waleed (2021) The role of relaxin family receptor 1 and 2 (RXFP1 and RXFP2) in gender- specific physiology and pathology. PhD thesis, University of Nottingham.

Almuhanna, Yasir Saleh I (2021) Role of lectin receptors in recognition of Pseudomonas aeruginosa biofilms. PhD thesis, University of Nottingham.

Ashford, Toni Winona Marie (2021) Towards an Understanding of the Role of VGF-Derived Peptides. MRes thesis, University of Nottingham.

Chen, Guanghua (2021) Lipid based interfacial design of food emulsion for controlling thelipolysis progress of GI-track. MPhil thesis, University of Nottingham.

Coughlan, J.L. (2021) Quantum biology to enhance CO2 fixation. MRes thesis, University of Nottingham.

Deo, Thomas Sandeep (2021) Applications of Dynamic nuclear polarisation in biological systems. PhD thesis, University of Nottingham.

Elsaied, Nashwa (2021) Characterisation of the anabolic effects of leucine on primary chicken muscle cells and murine C2C12 muscle cells. PhD thesis, University of Nottingham.

Glen, James (2021) Methodological Investigations Towards the Synthesis of Sesquiterpene-neolignans. MRes thesis, University of Nottingham.

Griffiths, Rhys (2021) Site-Selective Bioconjugation via Interception of Free-Radical-Induced Dechalcogenation. PhD thesis, University of Nottingham.

Gwilt, Miriam (2021) Keeping the balance - importance of balanced hippocampal neural activity for attention and memory. PhD thesis, University of Nottingham.

Haigh, Daisy (2021) Epitranscriptomic Determinants of Aggressive Prostate Cancer. PhD thesis, University of Nottingham.

Jenkins, T (2021) Analysis of catalytic and non-catalytic regions of the human DNA repair helicase HelQ. PhD thesis, University of Nottingham.

Lamont, Malcolm (2021) Virtual and in vitro screening of the Nottingham Managed Chemical Compound Collection vs Mycobacterium bovis and Mycobacterium tuberculosis cell wall biosynthesis enzyme: InhA. PhD thesis, University of Nottingham.

Latif, Arsalan (2021) Developing stromal instructive niches to promote wound healing. PhD thesis, University of Nottingham.

Li, Xinxin (2021) Interactions between rod-like biopolymer solutions and saliva. PhD thesis, University of Nottingham.

Liu, Ruiling (2021) Design, synthesis, and biological evaluation of PqsR antagonists guided by classic hit-to- lead optimisation process and fragment- based methods for the treatment of Pseudomonas aeruginosa infections. PhD thesis, University of Nottingham.

Mahri, Sohaib (2021) Mechanisms of retention of PEGylated recombinant human deoxyribonuclease i (rhDNase) in the lungs. PhD thesis, Université Catholique de Louvain and University of Nottingham.

Marshall, William (2021) Design, synthesis and pharmacological evaluation of novel fluorescent ligands for the mu-opioid receptor. PhD thesis, University of Nottingham.

Mashabi, Alaa (2021) Synthesis and biological evaluation of novel PqsR antagonists to combat Pseudomonas aeruginosa infections. PhD thesis, University of Nottingham.

Maurer, Sigrun (2021) Developing novel fusion tags to facilitate protein production and structure determination. PhD thesis, University of Nottingham.

Pabla, Pardeep (2021) Development of a liquid chromatography-mass spectrometry method to investigate branched chain amino acid and acylcarnitine metabolism in type 2 diabetes. PhD thesis, University of Nottingham.

Qin, Chaolong (2021) Targeting Lopinavir to the Mesenteric Lymphatic System by Lipophilic Ester Prodrug Approach for Improved Treatment of HIV/AIDS. PhD thesis, University of Nottingham.

Rehmani, Sahrish (2021) Developing an Oral-Insulin-Delivery System using GET-peptide-mediated transcytosis. PhD thesis, University of Nottingham.

Robinson, Henry Duncan (2021) Preparation of potent and selective αvβ6 integrin inhibitors for the treatment of idiopathic pulmonary fibrosis and synthetic approaches towards the total synthesis of mescengricin. PhD thesis, University of Nottingham.

Simmonds, Victoria (2021) Investigation of diffuse noxious inhibitory controls in the rat monosodium iodoacetate model of osteoarthritis pain. PhD thesis, University of Nottingham.

Tomlin, Hannah (2021) Engineering ‘extracellular matrix factories’ to study how the extracellular microenvironment regulates gene expression. PhD thesis, University of Nottingham.

Uras, G (2021) Evaluation of AChE inhibitors and dual AChE/GSK3-β inhibitor as Alzheimer’s disease treatment. PhD thesis, University of Nottingham.

Williamson, Daniel (2021) Quantitative analysis of fluorescence recovery after photobleaching and fluorescence loss in photobleaching, with a focus on the dynamics of yes-associated protein. PhD thesis, University of Nottingham.

Winlow, Poppy (2021) Investigation into the subcellular localisation and function of miR-122. PhD thesis, University of Nottingham.

Zordan, N (2021) Investigating how tenascin-C regulates miR-155 expression. PhD thesis, University of Nottingham.

Zyoud, Ahmad (2021) Defining the Role of piRNAs in Testicular Cancer. PhD thesis, University of Nottingham.

2020

Ahmad, Saeed (2020) Geochemical dynamics and bioavailability of iodine and selenium. PhD thesis, University of Nottingham.

Al-noori, Alaa (2020) Investigation of protein arginine methyltransferase bisubstrate inhibitors. PhD thesis, University of Nottingham.

Auvray, François (2020) Time-resolved synchrotron radiation circular dichroism spectroscopy. PhD thesis, University of Nottingham.

Azmir, Nur Amirah Hannan (2020) Methionine-aromatic interactions in ABCG2 influence mitoxantrone efflux. MRes thesis, University of Nottingham.

Clarkson, A.H. (2020) The copper conundrum: elucidating the modes of copper antagonism in the rumen. PhD thesis, University of Nottingham.

Dinu, Vlad (2020) Flavour-saliva interactions: implications of submaxillary mucin and α-amylase. PhD thesis, University of Nottingham.

Draycott, Sally Anne Victoria (2020) The effects of varying maternal dietary fat quantity and composition on disease programming in the offspring: a focus on essential fatty acids. PhD thesis, University of Nottingham.

Dutta, Shoma (2020) Histone modulation by nuclear localized meningococcal autotransporters. PhD thesis, University of Nottingham.

Goncalves da Silva, Ronni Anderson (2020) Elucidating the molecular mechanisms for lipoprotein processing and localisation of Factor H binding protein in Neisseria meningitidis. PhD thesis, University of Nottingham.

HALAWA, MOHAMED and UNSPECIFIED (2020) Novel fusion tags for protein production, purification and research applications. PhD thesis, University of Nottingham.

Huggett, Zoe (2020) Comparison of hepatoma cell lines and primary human hepatocytes as models to study the development of hepatic steatosis. PhD thesis, University of Nottingham.

Kapoor, Parth (2020) Elucidating the molecular mechanism of drug binding and translocation by the multidrug transporter ABCG2. PhD thesis, University of Nottingham.

Kok, Zhi Yuan (2020) Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor. PhD thesis, University of Nottingham.

Lau, Chun H. (2020) RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions. PhD thesis, University of Nottingham.

Metzler, Veronika (2020) Epigenetic coregulators of androgen signalling in prostate cancer. PhD thesis, University of Nottingham.

Quintero Barceinas, Reyna Sara (2020) The regulatory role of ELK-1 ubiquitination in cell proliferation and prostate cancer. PhD thesis, University of Nottingham.

Radley, Elizabeth H. (2020) The ‘dark matter’ of ubiquitin-mediated processes: using multiple approaches to investigate ubiquitin recognition. PhD thesis, University of Nottingham.

Richards, Philip J. (2020) Influence of dietary oligosaccharides on the gut microbiome. PhD thesis, University of Nottingham.

Roura Padrosa, David (2020) Overcoming emerging challenges in biocatalysis. PhD thesis, University of Nottingham.

Russo, Emanuele (2020) Bio-responsive hydrogels for an in vitro brain cancer cell model: self-controlled inhibition of matrix metalloproteinase activity. PhD thesis, University of Nottingham.

Slinger, Kimberley R. (2020) Optimisation and application of a method designed to assess host DNA in pig and poultry faeces as a potential marker of gut cell loss. PhD thesis, University of Nottingham.

Smith, Frances (2020) Macrocyclic peptides as inhibitors of protein-protein interactions. PhD thesis, University of Nottingham.

Spankie, Timothy J (2020) Interaction of the maturation protein of the bacteriophage MS2 and the F pilin of Escherichia coli. MRes thesis, University of Nottingham.

Stevenson, Matthew (2020) Design, synthesis, and evaluation of inhibitors of InhA to prevent cell wall biosynthesis in Mycobacterium bovis. PhD thesis, University of Nottingham.

Swainson, Sadie M E (2020) Development of a Size Targeted Formulation to Treat Pulmonary Arterial Hypertension. PhD thesis, University of Nottingham.

Sykes, David A (2020) A role for rebinding in the prevalence of on-target side effects of clinically used antipsychotics. PhD thesis, University of Nottingham.

2019

Al-Momani, Razan (2019) The role of SUMOylation in Liver X Receptor (LXR) transrepression of inflammatory responses. PhD thesis, University of Nottingham.

Caspar, Birgit (2019) Investigating the mode of action of intracellular loop 1 pepducins at the CXCR4 receptor. PhD thesis, University of Nottingham.

Evseev, Sergey (2019) Development and application of multiple isotopes-assisted untargeted metabolomics in human health and disease. PhD thesis, University of Nottingham.

Fyfe, Tim (2019) Medicinal Chemistry & Chemical Biology Approaches to Investigate Prospective Treatments for CNS Diseases: Dopamine D1 Receptor Positive Allosteric Modulators, Dopamine D2 Receptor Positive & Negative Allosteric Modulators, Dopamine D2 Receptor-Ligand Kinetics. PhD thesis, University of Nottingham.

Jaber, Malak (2019) Development and application of an enhanced lipidomic profiling methods using stable isotope-assisted LC-MS. PhD thesis, University of Nottingham.

Kaira, Bubacarr (2019) Structural Investigation of Zn2+ ions, FXII and Complement receptor gC1q-R interaction: Triggering the Contact activation System. PhD thesis, University of Nottingham.

Lishak, Jamie (2019) Examining the importance of survivin phosphorylation at Threonine 5 through its relationship with the kinase, TBK1, and the substrate, c-Src. MRes thesis, University of Nottingham.

Marples, Callum (2019) The Role of Aspherical Protein Shape: Dynamic Simulation of Ellipsoids. PhD thesis, University of Nottingham.

Mazumder, Bismoy (2019) Characterisation of the interaction interface of the MOZ/BRPF1 acetyltransferase complex and its role in gene regulation. PhD thesis, University of Nottingham.

Miller, Samuel Jacob (2019) Sustainable chemical synthesis using singlet oxygen. PhD thesis, University of Nottingham.

Mohd Amin, Nur Amalina (2019) Towards Polyionic Liquid-Based Supports for Application in Biocatalysis. PhD thesis, University of Nottingham.

Ng, Vivian (2019) Rational design, synthesis and in vitro antimicrobial activity of teixobactin analogues. PhD thesis, University of Nottingham.

Peel, Christopher (2019) Examining the substrate scope of transaminase variants derived from Vibrio fluvialis. PhD thesis, University of Nottingham.

Radhi, Masar (2019) Polyadenylation as a target for anti-inflammatory drugs. PhD thesis, University of Nottingham.

Saarti, Mohammed (2019) The effect of simvastatin on thromboxane-mediated contraction in porcine coronary artery: investigation of the role of mitochondria and extracellular calcium. PhD thesis, University of Nottingham.

Sanjuan Alberte, Paola (2019) Additive manufacturing of electrochemical systems and their application in bioelectronic medicine. PhD thesis, University of Nottingham.

Schoenfeld, Jonas (2019) Structure-Function analysis of a novel DNA-binding domain of the histone acetyltransferase MOZ/KAT6A. MRes thesis, University of Nottingham.

Ward, Stephanie (2019) Molecular characterisation of the Ubiquitin-specific protease 15 catalytic domain. PhD thesis, University of Nottingham.

Ziemann, Max (2019) 1-Hydroxy-xanthine Inhibitors of Caf1 Deadenylase as a Potential Treatment for Osteoporosis. PhD thesis, University of Nottingham.

2018

Ab Aziz, Muhamad Faris (2018) Effects of metabolic modifiers on lipogenic and lipolytic gene expressions in sheep. PhD thesis, University of Nottingham.

Abdulrazzaq, Ghayth (2018) Assessment of GPR18 pairing with putative cannabinoid ligands. PhD thesis, University of Nottingham.

Al Riyami, Bashair (2018) Effects of sex steroid hormones on acylation stimulating protein (ASP) and related gene expression. PhD thesis, University of Nottingham.

Almahasneh, Fatimah (2018) Effects of VEGF-A165b and SRPK1 inhibition on pain behaviour, cyclooxygenase expression and glial activation in the CNS in a model of osteoarthritis. PhD thesis, University of Nottingham.

Almousa, Lujain (2018) The effect of magnesium on the inflammatory response in human vascular endothelial cells. PhD thesis, University of Nottingham.

Almughem, Fahad (2018) Investigating novel cationic polymers for siRNA delivery for treatment of allergic disease. PhD thesis, University of Nottingham.

Almulathanon, Ammar (2018) Efficacy and toxicity of linear polyamidoamine polymers used in gene delivery. PhD thesis, University of Nottingham.

Alshahrani, Mohammad (2018) The role of C-type lectin receptors in the recognition of Pseudiminas aeruginosa. PhD thesis, University of Nottingham.

Annan, F.J. (2018) B-vitamin requirements of Clostridium autoethanogenum. PhD thesis, University of Nottingham.

Barbosa, Anne Caroline (2018) Using chromosome engineering on a natural isolate of the fission yeast, Schizosaccharomyces pombe, to investigate the epigenetic inheritance of the kinetochore. PhD thesis, University of Nottingham.

Bollard, Niall (2018) Characterisation of phosphotransferase systems (PTS) in Clostridium difficile. PhD thesis, University of Nottingham.

Brearley, Madelaine C. (2018) Mitochondrial phosphoenolpyruvate carboxykinase (PEPCK-M/PCK2), phosphoglycerate dehydrogenase (PHGDH) and muscle cell growth. PhD thesis, University of Nottingham.

Canning, Anne (2018) Enzyme responsive surfaces: towards a smart cell-material interface. PhD thesis, University of Nottingham.

Cardenas, Ryan (2018) Defining the role of miRNAs regulated by the pluripotency gene NANOG in the development and progression of testicular germ cell tumours. PhD thesis, University of Nottingham.

Catania, Rosa (2018) Glycoligands for targeted liposomes: design, development and ab-initio understanding of cell-vesicle recognition. PhD thesis, University of Nottingham.

Cheng, Huaitao (2018) Structure-function relationship of DEF6. PhD thesis, University of Nottingham.

Conroy, S. (2018) Design and synthesis of novel P2Y2 receptor ligands. PhD thesis, University of Nottingham.

Crowley, Darren Jerome (2018) Evolution of pluripotency: hijacking of an ancient network. PhD thesis, University of Nottingham.

Dhowre, Hala Shakib (2018) Surface chemistry guidance in controllable neural stem cell differentiation to direct stem cell fate: future applications in building artificial neural networks. PhD thesis, University of Nottingham.

Ducker, Charles (2018) Deubiquitination of ELK-1 by USP17 regulates its transcriptional potency and cell proliferation. PhD thesis, University of Nottingham.

Fathi, Zainab H (2018) Development and application of a linear polyamidoamine-SiRNA delivery system. PhD thesis, University of Nottingham.

Gao, Rui (2018) Design, synthesis, and optimisation of highly selective macrocyclic CDK9 inhibitors. PhD thesis, University of Nottingham.

Gowler, Peter (2018) Investigating the role of neurotrophins in the development of pain responses in animal models of joint pain. PhD thesis, University of Nottingham.

Hardcastle, MJ (2018) Structure, function and mechanism of beta-barrel protein assembly in Campylobacter jejuni. PhD thesis, University of Nottingham.

Hennessey, Anthony (2018) Statistical shape analysis of large molecular data sets. PhD thesis, University of Nottingham.

Ho, Johnathan (2018) The identification of STAT2 as a pervasive negative regulator of STAT1 activity and cytokine signalling. PhD thesis, University of Nottingham.

Hofmann, Saskia Iris (2018) The mouthfeel of black tea beverages. PhD thesis, University of Nottingham.

Imraish, Amer (2018) Age-related changes in the phenotype of microglia. PhD thesis, University of Nottingham.

Indrayudha, Peni (2018) Characterisation of the deubiquitinating enzyme USP4. PhD thesis, University of Nottingham.

Janes, George (2018) Factors regulating cortex cell file proliferation under low phosphorus stress in Arabidopsis thaliana roots. PhD thesis, University of Nottingham.

Jones, Graham Joseph (2018) Synthetic analogues of the nickel-iron hydrogenase family of metalloenzymes. PhD thesis, University of Nottingham.

Kajana, Sivarasa (2018) Investigating the role of proteins in melanosome transport. MRes thesis, University of Nottingham.

Kohli, Shivali (2018) The impact of oxytocin and GlyT1 inhibitors on social behaviour. PhD thesis, University of Nottingham.

Kumar, Sanjeeva (2018) Regulation of phosphatidylinositol 3-kinase (PI3K/Akt) pathway in chicken and duck cells and its implications for influenza A virus pathogenesis. PhD thesis, University of Nottingham.

Lane, Jordan Samuel (2018) Soluble modulators of intermolecular interactions in proteins and lipid rafts. PhD thesis, University of Nottingham.

Li, Zhuo (2018) Theoretical study of the circular dichroism spectroscopy of proteins. PhD thesis, University of Nottingham.

Lithgo, Ryan M. (2018) Hydrodynamic characterisation of high and low molecular weight glycans. MRes thesis, University of Nottingham.

Littledale, Charles (2018) Investigation of cilia-associated kinesin families. MPhil thesis, University of Nottingham.

Loreto, Andrea (2018) Mechanistic insights into an axon death pathway controlled by NAD-related metabolism. PhD thesis, University of Nottingham.

Marriott, Hannah (2018) Genome architecture and DNA replication in Haloferax volcanii. PhD thesis, University of Nottingham.

Martin, Eleyna (2018) Initiation of DNA replication in Bacillus subtilis: structural studies of the DnaA-DnaD interaction. PhD thesis, University of Nottingham.

McIvor, Emma (2018) Modelling store operated calcium entry: creating a three dimensional spatio-temporal model to predict local calcium signals. PhD thesis, University of Nottingham.

Moise, Eric Constantin (2018) Analysis of alpha defensin variation in samples from periodontitis patients. MRes thesis, University of Nottingham.

Monteiro, C.J. (2018) Function of MYST3 / MOZ: a histone acetyltransferase and chromatin regulator implicated in haematopoietic stem cell development and leukaemia. PhD thesis, University of Nottingham.

Olomu, Charles (2018) Molecular and metabolic regulation of skeletal muscle growth in chicken. PhD thesis, University of Nottingham.

Pander, Bart (2018) Nutrient limitation in Clostridium autoethanogenum and characterisation of its carbonic anhydrase. PhD thesis, University of Nottingham.

Parnall, Matthew (2018) Cardiac development in the chick embryo with reference to conduction and structure using a myosin heavy chain knock down model and global RNA sequencing in an outflow tract banded model. PhD thesis, University of Nottingham.

Parsons, Aimee (2018) The relationship between miRNA biogenesis and RNA splicing. PhD thesis, University of Nottingham.

Pavanello, Lorenzo (2018) Biochemical characterisation of the human Ccr4-Not complex: core complex assembly and deadenylation activity. PhD thesis, University of Nottingham.

Pickwell, Natalie Dawn (2018) Equine UDP-glucuronosyltransferases and their role in phase II metabolism. PhD thesis, University of Nottingham.

Planchestainer, Matteo (2018) H. elongata aminotransferase: a resourceful enzyme for modern biocatalysis. PhD thesis, University of Nottingham.

Rong, Fan (2018) Investigation of phosphate-regulatory transcription factors in wheat: TaPtf1 and TaMyb67. PhD thesis, University of Nottingham.

Saini, Kunal (2018) Investigation of role of Rab GTPases in fruit ripening in tomato (Solanum lycopersicum L.). PhD thesis, University of Nottingham.

Speakman, Abigail (2018) The role of MicroRNAs within extracellular vesicles in the creation of the pre-metastatic niche, for the development of prostate cancer metastasis to bone. MRes thesis, University of Nottingham.

Tilūnaitė, Agnė (2018) Modelling of intracellular calcium dynamics. PhD thesis, University of Nottingham.

Tong, Carmen (2018) Screening for inhibitors of Staphylococcal Sortase A as novel anti-infective agents. PhD thesis, University of Nottingham.

Turner, Jack (2018) Time resolved infrared studies of reactive intermediates. PhD thesis, University of Nottingham.

Veasy, Joshua (2018) Subcellular calcium patterns in ventricular myocytes. PhD thesis, University of Nottingham.

Wilhelmsen, Andrew (2018) Chronic effects of high intensity interval training on postprandial lipaemia in healthy individuals. MRes thesis, University of Nottingham.

Zhang, Juyang (2018) Sugar beet pectin–sodium caseinate conjugate stabilised emulsions: An investigation into the relationship between interfacial and bulk rheological properties for varying types of conjugates. PhD thesis, University of Nottingham.

Zhang, Mi (2018) Functional analysis of mRNA methylation in plants. PhD thesis, University of Nottingham.

2017

ALSHEHRI, ABDULLAH ALI D (2017) In-vitro investigations into endocytosis and silencing of siRNA-liposomes. PhD thesis, University of Nottingham.

Abbas, Z.S.B (2017) Identification and characterisation of the P2Y14 purine receptor in the porcine coronary artery. PhD thesis, University of Nottingham.

Airhihen, Blessing (2017) Molecular analysis of the Ccr4-Not deadenylase: relevance to human disease. PhD thesis, University of Nottingham.

Al-Ameedee, Mohammed (2017) Self-assembling tyrosine kinase inhibitors for localised targeted delivery. PhD thesis, University of Nottingham.

Al-Saad, Raghdan Zeki Chillab (2017) The development of Rab27-effector protein interaction inhibitors for treatment of cancer cell invasion and proliferation. PhD thesis, University of Nottingham.

Alam, K M Khairul (2017) Formulation and stabilization of protein-loaded nanoparticles and potential therapeutic applications thereof. PhD thesis, University of Nottingham.

Asghar, Muhammad Junaid (2017) Studies on the biased signalling of some novel delta opioid receptor agonists. PhD thesis, University of Nottingham.

Balacco, Dario Leonardo (2017) Analysis of the Ccr4-Not deadenylase complex: a biochemical and computational approach. PhD thesis, University of Nottingham.

Bestall, Samuel (2017) Diabetic neuropathy: a mechanism of TRPV1 sensitisation and the treatment with Vascular Endothelial Growth Factor-A165b (VEGF-A165b). PhD thesis, University of Nottingham.

Brailsford, Louis Alex (2017) Investigating the possible role of fatty acid binding proteins (FABPs) in nociceptive pain processing. PhD thesis, University of Nottingham.

Brunetti, Giulio (2017) CRISPR-Cas9-mediated genome editing of the extracellular matrix gene TNC in human fibroblasts. MRes thesis, University of Nottingham.

Buckley, Ryan J. (2017) Biochemical analysis of Hel308 and HelQ helicases. MRes thesis, University of Nottingham.

Clark, Marie A. (2017) Impact of replacing red and processed meat with non-meat alternatives on metabolic health. PhD thesis, University of Nottingham.

Clemente Olivo, Maria del Pilar (2017) Targeting BCL11A/nuclear receptor complexes in breast tumour cells using CRISPR-Cas9 genome editing tool. MRes thesis, University of Nottingham.

Cowling, Frances Natalie (2017) Phenolate and phenylthiolate ligand complexes containing Zn(II), Ni(II) and Cu(II). PhD thesis, University of Nottingham.

Dai, Yanzhenzi (2017) The role and regulation of insulin-like peptide 3 (INSL3) in the female reproductive system. PhD thesis, University of Nottingham.

Davis, Ben (2017) Stochastic epidemic models on random networks: casual contacts, clustering and vaccination. PhD thesis, University of Nottingham.

Girayer, Elif Naz (2017) Id4 functional analysis during neurogenesis using zebrafish as a model organism. MRes thesis, University of Nottingham.

Gopala Krishna, Varun (2017) Purification and characterisation of endogenous unanchored polyubiquitin. PhD thesis, University of Nottingham.

Hernández-Quiles, Miguel (2017) Targeting androgen receptor and PIP5K1A in prostate cancer cells using CRISPR-Cas9 genome editing tool. MRes thesis, University of Nottingham.

Husseini, Fouad (2017) Computing the two-dimensional infrared spectra of proteins and small peptides using the exciton approach and molecular dynamics simulations. PhD thesis, University of Nottingham.

IBRAHIM, DELVEEN (2017) Phenotypic and genotypic study of multidrug resistant, extended spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from a dairy farm. PhD thesis, University of Nottingham.

Jalali, Maryam (2017) Studying the cellular origin of HSCs in the zebrafish embryo and the role of Gfi1 transcription factors in their formation. PhD thesis, University of Nottingham.

Marshall, Eve (2017) Biomimetic approaches to tryptophan-derived alkaloids. PhD thesis, University of Nottingham.

Mohammed, Rabeea Hazim (2017) The IGF signalling factors during chick limb muscle development. PhD thesis, University of Nottingham.

Navarro Martínez, Ana (2017) Molecular mechanisms of modern and ancient Paget's disease. MRes thesis, University of Nottingham.

Newman, Christopher James (2017) Expression, purification and crystallisation of DNAse and immunity proteins in the S3 pyocin of Pseudomonas aeruginosa. MRes thesis, University of Nottingham.

Northall, Sarah (2017) Molecular analysis of human and archaeal DNA repair helicases HelQ and Hel308. PhD thesis, University of Nottingham.

Paschalis, Vasileios (2017) Revised model for the DNA replication fork in Bacillus subtilis: polymerase asymmetry. PhD thesis, University of Nottingham.

Powalowska, Paulina Klaudyna (2017) Development of ssRNA for therapeutic gene knock-down. PhD thesis, University of Nottingham.

Rich, Laura (2017) Schwann cell-axon metabolic interactions of the mouse sciatic nerve. MRes thesis, University of Nottingham.

Sanzà, Paolo (2017) The role of the guanine nucleotide exchange factor Rab3GEP in the regulation of Rab27a. PhD thesis, University of Nottingham.

Skelton, Gemma (2017) Synthetic analogues of the active site of [NiFe] hydrogenase. PhD thesis, University of Nottingham.

Slater, Alex (2017) Biophysical studies of the interaction between high molecular weight kininogen and gC1q-R : initiating the contact pathway. PhD thesis, University of Nottingham.

Smalley, Daniel. S. (2017) Translational control of epidermal growth factor receptor in neurodegenerative diseases. PhD thesis, University of Nottingham.

Taylor, Amelia C. (2017) Investigating the factors affecting adherence to inhaled corticosteroids in patients with asthma using primary care data in the UK. PhD thesis, University of Nottingham.

Umar, Aminu Argungu (2017) Role of intrinsic disorder in human exonuclease1 regulation. PhD thesis, University of Nottingham.

Welsh, Calum D.M. (2017) Infrared and multivariate studies of a biopolymer. PhD thesis, University of Nottingham.

Williamson, J J (2017) Investigation into the biotechnological applications of Pantoea agglomerans for the production of high value terpenoids such as taxadiene. PhD thesis, University of Nottingham.

2016

Al-Rashed, Fatema (2016) The role of lipid toxicity and para-inflammation as potential mechanisms of age related macular degeneration. PhD thesis, University of Nottingham.

Alharbi, Laila (2016) In vitro and in ex vivo effects of vitamin D on regulation of vascular tone. PhD thesis, University of Nottingham.

Askar, Basim Ali (2016) The therapeutic potential of vasoactive intestinal peptide (VIP) in the treatment of Gram-negative sepsis. PhD thesis, University of Nottingham.

Bahrami, Niloufar (2016) Impact of wheat lipids on the functionality of wheat flour. PhD thesis, University of Nottingham.

Baker, Amanj (2016) Investigating the implementation and impact of “Better Care Better Value” prescribing policy for Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers for treating hypertension in the UK primary care setting. PhD thesis, University of Nottingham.

Caulton, Simon (2016) Characterisation of the deubiquitinating enzyme USP20. PhD thesis, University of Nottingham.

Clifford, Bethan L. (2016) The distribution and expression of the nitric oxide system during renal ageing and the effect of sex steroid modulation. PhD thesis, University of Nottingham.

Dahabiyeh, Lina (2016) Targeted mass spectrometry for plasma glycoprotein profiling in pre-eclampsia. PhD thesis, University of Nottingham.

Denyer, Tom (2016) The role of microRNAs in Arabidopsis lateral root development. PhD thesis, University of Nottingham.

Dhanaseelan, Tamilvendhan (2016) TALEN-mediated site-directed mutagenesis of HLH proteins lyl1 and Id4 to reveal their role in haematopoietic and neural stem cell fate. PhD thesis, University of Nottingham.

Dunajova, Lucia (2016) The role of mitochondrial survivin in phospholipid biosynthesis. PhD thesis, University of Nottingham.

Elfsei, Khalid (2016) Pharmacological characterization of annexin A2-S100A10 interaction in pancreatic cancer using 1,5-dihydro-pyrrol-2-one compounds. PhD thesis, University of Nottingham.

Eltaher, Hoda M.M.A. (2016) Gradient delivery of bioactive molecules across porous hydrogels. PhD thesis, University of Nottingham.

England, Jennifer (2016) The role of thin filament sarcomeric proteins tropomyosin 1 and cardiac troponin T in the developing heart. PhD thesis, University of Nottingham.

Erten, Tayyibe (2016) A hydrodynamic study of microbial polysaccharides considered for use in food and health products. PhD thesis, University of Nottingham.

Grazette, Affif (2016) Molecular characterisation of squamous cell carcinoma antigen recognised by T-cells 3, an adaptor protein of ubiquitin specific protease 15. PhD thesis, University of Nottingham.

Hames, Tim (2016) Playing Tetris with porphyrins: the synthesis of porphyrinic materials for self-sssembly studies. PhD thesis, University of Nottingham.

Handzlik, Michal (2016) Cardiac responses to hypoxia: the role of pyruvate dehydrogenase complex in carbohydrate utilisation. PhD thesis, University of Nottingham.

Hill, Rachel E. (2016) Computational studies of the dynamics and spectroscopy of peptides. PhD thesis, University of Nottingham.

Kareem Hamad, B. (2016) Molecular pharmacological studies of CHFI-FXII interaction and FXII function. PhD thesis, University of Nottingham.

Khalaf, Ahmed Hassanein Abdelmaksoud (2016) Post-translational modification of Interferon Regulatory Factor 1 (IRF1). MRes thesis, University of Nottingham.

Krupa, James L. (2016) Design, synthesis and evaluation of MRI ligands for in vivo imaging of protease activity. PhD thesis, University of Nottingham.

Lam, Chi Man (2016) The regulation of Sox3 function in zebrafish embryonic development. PhD thesis, University of Nottingham.

Maclennan, Richard Alexander (2016) Activation of constitutive androstane receptor (CAR) in primary human hepatocytes. PhD thesis, University of Nottingham.

Madeira do Ó, João (2016) Applications of glycopolymer libraries as protein aggregation modulators and drug delivery systems. PhD thesis, University of Nottingham.

May, Terry J. (2016) Synthesis and evaluation of inhibitors of cell wall biosynthesis in Mycobacterium tuberculosis. PhD thesis, University of Nottingham.

Moore, Jonathan Christopher (2016) Studies towards the biomimetic synthesis of members of the kingianin family of natural products. PhD thesis, University of Nottingham.

Morgan, J. (2016) Biophysical studies of the ligand-affinity & binding of leukocyte integrin Mac-1 I-domain: an open & closed case? PhD thesis, University of Nottingham.

Ogbu, H.I. (2016) Amino acids utilisation by Clostridium difficile strains. PhD thesis, University of Nottingham.

Orr, Catherine (2016) Characterisation of equine cytochrome P450s. PhD thesis, University of Nottingham.

Parker, Hannah (2016) Control of poly(A) tail metabolism during inducible gene expression. PhD thesis, University of Nottingham.

Raulo, Roxane (2016) Expression of glycoside hydrolases in Aspergillus niger. PhD thesis, University of Nottingham.

Robinson, Christopher L. (2016) MyosinVa and dynamic actin oppose minus-end directed microtubule motors to drive anterograde melanosome transport. PhD thesis, University of Nottingham.

Rossi, Francesca (2016) NMNAT1 and its role on ageing and age-realted diseases. PhD thesis, University of Nottingham.

SARWAT, SUNEHERA (2016) Trials and tribulations in the expression and purification of ABCG2. MRes thesis, University of Nottingham.

Salih, Twana (2016) Inhibiting protein–protein interactions in telomeres as an approach to cancer chemotherapy. PhD thesis, University of Nottingham.

Shannon, C.E. (2016) Skeletal muscle carnitine metabolism during intense exercise in human volunteers. PhD thesis, University of Nottingham.

Shemiss, Ligia (2016) Probing the role of organic cation transporters in respiratory epithelial cell proliferation in vitro. PhD thesis, University of Nottingham.

Silistre, Hazel (2016) Riboregulation in Pseudomonas aeruginosa. PhD thesis, University of Nottingham.

Sparrow, Alexander (2016) LIM kinase and metanephric mesenchymal cell migration in the developing mouse kidney. PhD thesis, University of Nottingham.

Stock, Jessica (2016) Characterisation of the unique large Armadillo repeat protein (LARP) in the malaria parasite Plasmodium berghei. MRes thesis, University of Nottingham.

2015

Al-Doski, Shaker (2015) Effects of growth promoters on sheep metabolism and growth. PhD thesis, University of Nottingham.

Almutairi, Fahad Mohammed (2015) A molecular hydrodynamic study of marine based non-digestible fibre polysaccharides considered for use in health products. PhD thesis, University of Nottingham.

Brown, David M. (2015) Molecular regulation of skeletal muscle myosin heavy chain isoforms. PhD thesis, University of Nottingham.

Giles, Timothy Andrew (2015) Development of a DNA-based microarray for the detection of zoonotic pathogens in rodent species. PhD thesis, University of Nottingham.

Gillis, Richard Benjamin (2015) Protein polysaccharide complexes: permanent/nonpermanent interactions between polysaccharides and polypeptides. PhD thesis, University of Nottingham.

Kilpatrick, Laura Elise (2015) The use of bimolecular fluorescence complementation (BiFC) to investigate the functional implications of neuropeptide Y receptor dimerisation and beta-arrestin recruitment. PhD thesis, University of Nottingham.

Kwok, C. (2015) Postnatal maturation of the opioid and endocannabinoid signalling systems within the descending pain pathway of the rat. PhD thesis, University of Nottingham.

Lewis, Jo Edward (2015) The role of VGF and its derived peptides in the regulation of energy homeostasis. PhD thesis, University of Nottingham.

Maddinapudi, Sri L P (2015) Genetic analyses of pre-meiotic DNA replication in Saccharomyces cerevisiae. PhD thesis, University of Nottingham.

Maryati, Maryati (2015) Biochemical analysis of the nuclease module of the human Ccr4-Not deadenylase complex. PhD thesis, University of Nottingham.

Priestley, Richard (2015) A study of functional selectivity at the cannabinoid type 1 receptor. PhD thesis, University of Nottingham.

Seamons, Laura Elizabeth (2015) The role of very long chain fatty acids in Arabidopsis growth and development. PhD thesis, University of Nottingham.

Utami, Wahyu (2015) Ion pairing LC-MS/MS method for analysis of intracellular phosphorylated metabolites. PhD thesis, University of Nottingham.

Wong, Kelvin (2015) Dynamics and oligomerisation of ABCG2 investigated using various fluorescence techniques. PhD thesis, University of Nottingham.

Wong, Pui San (2015) Sex differences in endothelial function in the porcine coronary artery. PhD thesis, University of Nottingham.

Xu, Xiaoou (2015) Swap70b acts downstream of Wnt11 signalling to regulate zebrafish convergence and extension cell movements. PhD thesis, University of Nottingham.

Zhu, Jing (2015) Polymer-mediated crystallisation of proteins. PhD thesis, University of Nottingham.

2014

Kirby, Giles T.S. (2014) Development of a growth factor delivery system. PhD thesis, University of Nottingham.

Lavado, Andrea Sofia Caetano das Neves (2014) Porphyrinic-nanoplatforms: controlled intracellular generation of reactive oxygen species in human mesenchymal stem cells. PhD thesis, University of Nottingham.

Shen, Yuan (2014) Evolution of the TGF-beta superfamily with emphasis on Nodal. MPhil thesis, University of Nottingham.

Shermado, Fairouz M. (2014) Molecular characterization of cannabinoids and free fatty acid receptors in human and rat skeletal muscle. PhD thesis, University of Nottingham.

Zakoko, Ahmed Mahmoud (2014) Investigation of diverse polyubiquitin chains in the mouse brain using ubiquitin binding domains. PhD thesis, University of Nottingham.

2013

Adlington, Jennifer (2013) Ubiquitin binding by the p62 UBA domain. PhD thesis, University of Nottingham.

Ahmad, Omar Akram Jerjees (2013) Identification of novel transcripts of CHRNA7 and CHRFAM7A in airway epithelial cells. PhD thesis, University of Nottingham.

Al-Azzawi, Haneen (2013) Cytosine methylation and hydroxymethylation at the leptin promoter. PhD thesis, University of Nottingham.

Barros, Fabrício Félix Tabuada (2013) Biological characterisation of HER2 amplified breast cancer. PhD thesis, University of Nottingham.

Chatwell, Nicola (2013) Nucleic acid approaches to toxin detection. MPhil thesis, University of Nottingham.

Cox, Helen Celia (2013) A biodegradable system for the tailored delivery of growth factors and its application to bone morphogenetic protein-2 delivery for bone repair. PhD thesis, University of Nottingham.

Doidge, Rachel L. (2013) The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7)/Caf1b (CNOT8) deadenylase enzymes. PhD thesis, University of Nottingham.

Domingues Goncalves, Andrea (2013) Understanding the rheology of liquid protein formulations. PhD thesis, University of Nottingham.

Edwards, John Michael (2013) Binding interactions of the mRNA regulator CELF1. PhD thesis, University of Nottingham.

Gorny, Samuel Victor (2013) The nematicidal effect of cysteine proteinases on the root knot nematode Meloidogne incognita. PhD thesis, University of Nottingham.

Hassan, Samia (2013) Effect of cannabinoid receptor ligands on microglial cell functions. PhD thesis, University of Nottingham.

Jackson, Thomas John (2013) Translational control : mTOR signalling and the use of next-generation sequencing methods. PhD thesis, University of Nottingham.

Lake, David Jonathan (2013) A human alpha-arrestin protein with a potential role in cargo protein trafficking within the endocytic system. PhD thesis, University of Nottingham.

Luoga, Wenceslaus (2013) Factors affecting the anthelmintic efficacy of cysteine proteinases against GI nematodes and their formulation for use in ruminants. PhD thesis, University of Nottingham.

Magennis, Eugene Peter (2013) Bacterial auto-nemesis: templating polymers for cell sequestration. PhD thesis, University of Nottingham.

Malik, Adnan Mahmood (2013) Design, synthesis and evaluation of inhibitors of POT1-DNA interactions. PhD thesis, University of Nottingham.

Mareckova, Klara (2013) Sex differences and the role of sex hormones in face development and face processing. PhD thesis, University of Nottingham.

Marelli, Elisa (2013) From sequence to function: analysis of Sox3 during early zebrafish development. MRes thesis, University of Nottingham.

Prokopiou, Sotiris (2013) Integrative modelling of angiogenesis in the bovine corpus luteum. PhD thesis, University of Nottingham.

Russell, Daniel John (2013) Lycopene carotenogenesis and function in the haloarchaeon Haloferax volcanii. PhD thesis, University of Nottingham.

Speed, Daniel (2013) A click-chemistry based approach for the synthesis of new BODIPY-labelled fluorescent ligands. PhD thesis, University of Nottingham.

Tie, Ding Yee (2013) Design and synthesis of indole-thiazole based inhibitors of UDP-galactopyranose mutase. MSc(Res) thesis, University of Nottingham.

Turpin, Eleanor R. (2013) Computational studies of folding and binding of polypeptides. PhD thesis, University of Nottingham.

Watson, Sarah-Jane (2013) Pharmacological characterisation of the fatty acid receptors GPR120 and FFA1. PhD thesis, University of Nottingham.

2012

Abd Manap, Mohd Nazmi (2012) Functional polymorphisms : bovine calpastatin gene and meat tenderness. PhD thesis, University of Nottingham.

Aleanizy, Fadilah (2012) Investigating the molecular mechanisms of colicin import into Escherichia coli cells. PhD thesis, University of Nottingham.

Deeves, Sian Elizabeth (2012) Novel functions of the MOZ double PHD finger domain. PhD thesis, University of Nottingham.

Evans, Richard Debney (2012) The role of glycogen and lactate in supporting action potential conduction in mouse central white matter and peripheral nerve. PhD thesis, University of Nottingham.

Ferguson, Alison (2012) Identification and characterisation of Arabidopsis ER accessory proteins. PhD thesis, University of Nottingham.

Haddad, Mansour Emil Goerge (2012) GPCRs in rat primary skeletal muscle cells. PhD thesis, University of Nottingham.

Hutter, Victoria (2012) Characterisation of ATP-binding cassette (ABC) transporters in bronchial epithelial cell culture models. PhD thesis, University of Nottingham.

Johnston, Richard David (2012) Nutritional modulation of hepatic lipid metabolism in health and disease. DM thesis, University of Nottingham.

Kalamaras, Konstantinos (2012) The role of adiponectin in regulation of metabolism in dairy cows. PhD thesis, University of Nottingham.

Liu, Xiangrui (2012) Evaluation of transcriptional cyclin dependent kinase inhibitors as potential cancer therapeutics. PhD thesis, University of Nottingham.

Lovelock, Laura Charlotte (2012) RsmN : a new atypical RsmA homologue in Pseudomonas aeruginosa. PhD thesis, University of Nottingham.

Portman, Katherine Louise (2012) Characterising the binding interactions and thermodynamics of odour binding protein 3. PhD thesis, University of Nottingham.

Roy, Julie (2012) Ligand recognition by the major urinary protein. PhD thesis, University of Nottingham.

Thambyrajah, Roshana Sutharshini (2012) A gene trap screen reveals the expression of the transcription factor Gfi1.1 in haemogenic endothelial cells of the Zebrafish embryo. PhD thesis, University of Nottingham.

Wall, Richard John (2012) Potency and species specificity of aryl hydrocarbon receptor ligands. PhD thesis, University of Nottingham.

Webb, Thomas E. (2012) Understanding the role of eIF4A in gene regulation in health and disease. PhD thesis, University of Nottingham.

Williams, Leanne (2012) The role of aquaporins in the developing ovarian follicle. PhD thesis, University of Nottingham.

Wong, Amy (2012) The role of bioactive lipids in pain and inflammation. PhD thesis, University of Nottingham.

2011

Chilimba, Allan Dennies Colex (2011) Potential for safe and efficient biofortification of maize crops with selenium in Malawi. PhD thesis, University of Nottingham.

Dickens, Michael (2011) Small molecule inhibitors of Mdm2 E3 ubiquitin ligase activity. PhD thesis, University of Nottingham.

Fitzgerald, Ross Patrick (2011) Small molecule inhibitors of the p53-MDM2 protein-protein interaction. PhD thesis, University of Nottingham.

Garner, Thomas Peter (2011) Structural and biophysical investigations into ubiquitin binding proteins. PhD thesis, University of Nottingham.

Phillips, Nicola Marie (2011) Investigations of the DEAD-box helicase eIF4A. PhD thesis, University of Nottingham.

Refaey, Rana Hosny (2011) Structural and mechanistic studies of quinone oxidoreductase II : NQO2. PhD thesis, University of Nottingham.

Spencer, Sarah Jane (2011) Novel fenofibrate derivatives as cannabinoid receptor ligands. PhD thesis, University of Nottingham.

Tarabees, Reda Zakaria Ibrahim (2011) Endotoxin induced muscle wasting in avian and murine skeletal muscle. PhD thesis, University of Nottingham.

Vargas Bello Pérez, Einar (2011) Plasma transport and mammary uptake of trans fatty acids in dairy cows. PhD thesis, University of Nottingham.

Williams, Haydn Wyn (2011) Computer simulations of protein folding. PhD thesis, University of Nottingham.

Wu, Yanqi (2011) New methods for measuring CSA tensors : applications to nucleotides and nucleosides. PhD thesis, University of Nottingham.

Xu, Kairuo (2011) Characterization and utilization of self-assembled diphenylalanine nanotubes. PhD thesis, University of Nottingham.

Ó Lochlainn, Seosamh (2011) Natural genetic variation in zinc (Zn) accumulation in Brassicaceae. PhD thesis, University of Nottingham.

2010

Abilgos Ramos, Riza (2010) Folate profiling in wild and transgenic rice. PhD thesis, University of Nottingham.

Anukul, Nampeung (2010) Genetic manipulation of folate in rice. PhD thesis, University of Nottingham.

Craggs, Lucinda (2010) Manipulation of growth & meat quality by vitamin D and its analogues. PhD thesis, University of Nottingham.

Dey, Sabrina (2010) Thermo-responsive surfaces for enzyme free mammalian cell culture. PhD thesis, University of Nottingham.

Duduială, Ciprian Ionut (2010) Stochastic nonlinear models of DNA breathing at a defect. PhD thesis, University of Nottingham.

Garside, Paul (2010) Analysis of the canonical initiation and trans-acting factor requirements of 5'TOP containing mRNAs. PhD thesis, University of Nottingham.

Gutteridge, Eleanor (2010) An investigation into the effects of the epidermal growth factor receptor tyrosine kinase inhibitor "Gefitinib" on human breast cancer. DM thesis, University of Nottingham.

Huang, Xingye (2010) Chiral separation of pharmaceuticals by capillary electrophoresis. PhD thesis, University of Nottingham.

Mills, Victoria (2010) Zinc hyperaccumulation in Thlaspi caerulescens. PhD thesis, University of Nottingham.

Mirotti, Luciana Cristina (2010) The role of natural lipids in an in vivo model of sensitisation to Ber e 1. PhD thesis, University of Nottingham.

Patel, Annie (2010) Endocannabinoid turnover and function. PhD thesis, University of Nottingham.

Staniaszek, Lydia Ewa (2010) An investigation of pain mechanisms in a model of osteoarthritis : modulation by the endocannabinoid receptor system. PhD thesis, University of Nottingham.

Tunio, Sarfraz Ali (2010) Molecular and immunological characterization of glycolytic enzymes : FBA and GAPDH-1 of Neisseria meningitidis. PhD thesis, University of Nottingham.

Vllasaliu, Driton (2010) In vitro investigation into strategies for mucosal delivery of proteins. PhD thesis, University of Nottingham.

2009

Bulheller, Benjamin M. (2009) Circular and linear dichroism spectroscopy of proteins. PhD thesis, University of Nottingham.

Christensen, Peter (2009) Hybrid quadrupole linear ion trap mass spectrometry : application to metabolites. PhD thesis, University of Nottingham.

Hall, Andrew J. (2009) Mammalian chitotriosidase and its role in innate immunity. PhD thesis, University of Nottingham.

Harrison, Matthew James (2009) Intergenerational programming of impaired nephrogenesis and hypertension in rats following maternal protein restriction during pregnancy. PhD thesis, University of Nottingham.

Holt, Christopher James (2009) Design, synthesis and evaluation of fluorescent CB2 cannabinoid receptor ligands. PhD thesis, University of Nottingham.

Koliandris, Andreas (2009) Relationship between texture of gels and flavour release. PhD thesis, University of Nottingham.

Niu, Lijiang (2009) Investigating self-assembled protein nanotubes using atomic force microscopy. PhD thesis, University of Nottingham.

Rochette, Sophie (2009) Structural and functional studies on lysostaphin, an antistaphylococcal endopeptidase. PhD thesis, University of Nottingham.

Tseng, Hua-Ming (2009) Capillary electrophoresis with laser-induced fluorescence detection used in metabolite profiling. PhD thesis, University of Nottingham.

Zelzer, Mischa (2009) Plasma polymer gradients : developing a tool for the screening of biological responses to surfaces. PhD thesis, University of Nottingham.

2008

Collis, Alana E.C. (2008) The synthesis of vinylphosphonate-linked RNA. PhD thesis, University of Nottingham.

Coupland, Paul (2008) Targeted fluorescent optical nanosensors for imaging and measuring function in intracellular microdomains. PhD thesis, University of Nottingham.

Lone, Mudasir (2008) Investigation of the temperature dependence of single molecule biomolecular interactions. MRes thesis, University of Nottingham.

2007

Alsayeqh, Abdullah Fayez (2007) Activation of the transcription factor NF-kB by Campylobacter jejuni. PhD thesis, University of Nottingham.

Handley, Kelly (2007) Statistical analysis of proteomic mass spectrometry data. PhD thesis, University of Nottingham.

Schneider, Sabine (2007) Structural and Biochemical Studies on Novel Bacterial Haem-Proteins. PhD thesis, University of Nottingham.

2006

Fee, Monica (2006) Evaluation of chitosan stability in aqueous systems. PhD thesis, University of Nottingham.

Johnson, Daniel (2006) Molecular level investigations of coiled-coil proteins. PhD thesis, University of Nottingham.

2005

Al-Anizy, Mohammed (2005) Studies on Cytochrome P450 4X1. PhD thesis, University of Nottingham.

Flux, Claire Louise (2005) The effect of conjugated linoleic acid on lipid metabolism in the hamster and the sheep. PhD thesis, University of Nottingham.

Hands, Sarah Louise (2005) Biophysical investigations of the mechanism of colicin translocation. PhD thesis, University of Nottingham.

Slee, Adrian (2005) Regulation of skeletal muscle proteolysis. PhD thesis, University of Nottingham.

Yates, Andrew Stephen (2005) Fluorescent cannabinoids: Stratagies towards the synthesis of fluorescently labelled CB2 receptor ligands. PhD thesis, University of Nottingham.

2004

Gallagher, Cathal T (2004) NMR Studies of Nucleic Acids as Drug Targets. PhD thesis, University of Nottingham.

Gharib Abdelhady, Hosam (2004) Investigation of polyamidoamine dendrimers induced DNA condensation and enzymatic degradation of these complexes: an atomic force microscopy study. PhD thesis, University of Nottingham.

Ridley, Kristian (2004) Functional characterisation of ABC-type metal ion uptake systems in the staphylococci. PhD thesis, University of Nottingham.

Williams, Richard David (2004) Immunomodulation of reproductive function in domestic ruminants. PhD thesis, University of Nottingham.

2003

Crepin, Valérie (2003) Ferulic acid esterases for effective processing of plant carbohydrates. PhD thesis, University of Nottingham.

2002

Fan, MingQi (2002) Studies of The Structure of Cytochrome P450 4A1. PhD thesis, University of Nottingham.

Gavathiotis, Evripidis (2002) Drug-targetting of duplex and quadruplex DNA. PhD thesis, University of Nottingham.

Mee, Christopher (2002) Molecular Genetic Analysis of the alpha-latrotoxin Receptor Latrophilin in the Nematode Caenorhabditis elegans. PhD thesis, University of Nottingham.

2001

De Bank, Paul A. (2001) Synthesis and biological evaluation of novel compounds as potential modulators of cannabinoid signalling pathways. PhD thesis, University of Nottingham.

Kennedy, Ann (2001) Protein engineering of an industrially-used lipase. PhD thesis, University of Nottingham.

Morris, Gordon Alistair (2001) Hydrodynamic investigation of polysaccharides and their interaction with casein. PhD thesis, University of Nottingham.

Williams, Huw Edward Llewelyn (2001) Structure, dynamics and hydration in drug-DNA recognition. PhD thesis, University of Nottingham.

2000

Marshall, Paul (2000) The internal properties of the bioadhesive bond. PhD thesis, University of Nottingham.

1999

Horley, Neill (1999) Molecular Basis of CYP2B2 Induction. PhD thesis, University of Nottingham.

1998

Boxall, Jon Graham (1998) Glutamine synthetase of Lotus corniculatus roots and nodules: characterisation and tissue-specific inhibition. PhD thesis, University of Nottingham.

1997

Heng, Yee M. (1997) Genomic cloning and identification of a novel murine Cyp4a gene. PhD thesis, University of Nottingham.

1996

Farhat, Imad Akil (1996) Molecular mobility and interactions in biopolymer-sugar-water systems. PhD thesis, University of Nottingham.

Farhat, Imad Akil (1996) Molecular mobility and interactions in biopolymer-sugar-water systems. PhD thesis, University of Nottingham.

Hinchcliffe, Michael (1996) The novel application of chitosan for the intranasal delivery of insulin. PhD thesis, University of Nottingham.

1995

Kelly, Rachel Jane (1995) Functional behaviour of mixed protein-polysaccharide system. PhD thesis, University of Nottingham.

Uysal, Hamdi (1995) Extracellular matrix glycoproteins of skin fibroblasts in tuberous sclerosis. PhD thesis, University of Nottingham.

1994

Guven, Kemal (1994) Invertebrate stress responses as molecular biomarkers in ecotoxicology. PhD thesis, University of Nottingham.

Jumel, Kornelia (1994) Molecular size of interacting and degrading polysaccharides. PhD thesis, University of Nottingham.

1993

Scanlon, Martin J. (1993) Structural studies of MUC1 core related peptides. UNSPECIFIED thesis, University of Nottingham.

1991

Hesketh, Andrew R. (1991) Metabolic studies on the transformation of trichodiene to trichothecene mycotoxins. PhD thesis, University of Nottingham.

Smith, Lesley Mary (1991) Evaluation of an in vitro cytotoxicity assay for specific groups of chemicals. PhD thesis, University of Nottingham.

1990

Hammond, Alison H. (1990) Cytochrome P450-mediated metabolism and cytotoxicity in rat cultured hepatocytes. PhD thesis, University of Nottingham.

1989

Thompson, Shirley Patricia (1989) Calcium homeostasis in the elderly. PhD thesis, University of Nottingham.

1983

James, Michael John (1983) The thermodynamics of partitioning of phenolic compounds between aqeous solution and model membrane systems. PhD thesis, University of Nottingham.