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Ahuja, Sunil K., Wain, Louise V., Odenthal-Hesse, Linda, Abujaber, Razan, Sayers, Ian, Beardsmore, Caroline, Gaillard, Erol A., Chappell, Sally, Dogaru, Cristian M., McKeever, Tricia M., Guetta-Baranes, Tamar, Kalsheker, Noor, Kuehni, Claudia E., Hall, Ian P., Tobin, Martin D. and Hollox, Edward J. (2014) Copy number variation of the beta-defensin genes in Europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma. PLoS ONE, 9 (1). e84192/1-e84192/8. ISSN 1932-6203

Allen, Richard J., Porte, Joanne, Braybrooke, Rebecca, Flores, Carlos, Fingerlin, Tasha E., Oldham, Justin M., Guillen-Guio, Beatriz, Ma, Shwu-Fan, Okamoto, Tsukasa, John, Alison E., Obeidat, Ma'en, Yang, Ivana V., Henry, Amanda, Hubbard, Richard B., Navaratnam, Vidya, Saini, Gauri, Thompson, Norma, Booth, Helen L., Hart, Simon P., Hill, Mike R., Hirani, Nik, Maher, Toby M., McAnulty, Robin J., Millar, Ann B., Molyneaux, Philip L., Parfrey, Helen, Rassl, Doris M., Whyte, Moira K.B., Fahy, William A., Marshall, Richard P., Oballa, Eunice, Bossé, Yohan, Nickle, David C., Sin, Don D., Timens, Wim, Shrine, Nick, Sayers, Ian, Hall, Ian P., Noth, Imre, Schwartz, David A., Tobin, Martin D., Wain, Louise V. and Jenkins, R. Gisli (2017) Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. Lancet Respiratory Medicine, 5 (11). pp. 869-880. ISSN 2213-2619

Anderson, J.R., Mortimer, K., Pang, Linhua, Smith, K.M., Bailey, H., Hodgson, D.B., Shaw, Dominick E., Knox, Alan J. and Harrison, Timothy W. (2016) Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial. PLoS ONE, 11 (8). e0160257/1-e0160257/15. ISSN 1932-6203

Artigas, María Soler, Wain, Louise V., Miller, Suzanne, Kheirallah, Abdul Kader, Huffman, Jennifer E., Ntalla, Ioanna, Shrine, Nick, Obeidat, Ma’en, Trochet, Holly, McArdle, Wendy L., Alves, Alexessander Couto, Hui, Jennie, Zhao, Jing Hua, Joshi, Peter K., Teumer, Alexander, Albrecht, Eva, Imboden, Medea, Rawal, Rajesh, Lopez, Lorna M., Marten, Jonathan, Enroth, Stefan, Surakka, Ida, Polasek, Ozren, Lyytikäinen, Leo-Pekka, Granell, Raquel, Hysi, Pirro G., Flexeder, Claudia, Mahajan, Anubha, Beilby, John, Bossé, Yohan, Brandsma, Corry-Anke, Campbell, Harry, Gieger, Christian, Gläser, Sven, González, Juan R., Grallert, Harald, Hammond, Chris J., Harris, Sarah E., Hartikainen, Anna-Liisa, Heliövaara, Markku, Henderson, John, Hocking, Lynne, Horikoshi, Momoko, Hutri-Kähönen, Nina, Ingelsson, Erik, Johansson, Åsa, Kemp, John P., Kolcic, Ivana, Kumar, Ashish, Lind, Lars, Melén, Erik, Musk, Arthur W., Navarro, Pau, Nickle, David C., Padmanabhan, Sandosh, Raitakari, Olli T., Ried, Janina S., Ripatti, Samuli, Schulz, Holger, Scott, Robert A., Sin, Don D., Starr, John M., Deloukas, Panos, Hansell, Anna L., Hubbard, Richard, Jackson, Victoria E., Marchini, Jonathan, Pavord, Ian, Thomson, Neil C., Zeggini, Eleftheria, Viñuela, Ana, Völzke, Henry, Wild, Sarah H., Wright, Alan F., Zemunik, Tatijana, Jarvis, Deborah L., Spector, Tim D., Evans, David M., Lehtimäki, Terho, Vitart, Veronique, Kähönen, Mika, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Karrasch, Stefan, Probst-Hensch, Nicole M., Heinrich, Joachim, Stubbe, Beate, Wilson, James F., Wareham, Nicholas J., James, Alan L., Morris, Andrew P., Jarvelin, Marjo-Riitta, Hayward, Caroline, Sayers, Ian, Strachan, David P., Hall, Ian P. and Tobin, Martin D. (2015) Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6 . 8658/1-8658/12. ISSN 2041-1723

Artigas, María Soler, Wain, Louise V., Shrine, Nick, McKeever, Tricia M., Sayers, Ian, Hall, Ian P. and Tobin, Martin D. (2017) Targeted sequencing of lung function loci in chronic obstructive pulmonary disease cases and controls. PLoS ONE, 12 (1). e0170222/1-e0170222/17. ISSN 1932-6203

Aschard, Hugues, Tobin, Martin D., Hancock, Dana B., Skurnik, David, Sood, Akshay, James, Alan, Vernon Smith, Albert, Manichaikul, Ani W., Campbell, Archie, Prins, Bram P., Hayward, Caroline, Loth, Daan W., Porteous, David J., Strachan, David P., Zeggini, Eleftheria, O’Connor, George T., Brusselle, Guy G., Boezen, H. Marike, Schulz, Holger, Deary, Ian J., Hall, Ian P., Rudan, Igor, Kaprio, Jaakko, Wilson, James F., Wilk, Jemma B., Huffman, Jennifer E., Hua Zhao, Jing, de Jong, Kim, Lyytikäinen, Leo-Pekka, Wain, Louise V., Jarvelin, Marjo-Riitta, Kähönen, Mika, Fornage, Myriam, Polasek, Ozren, Cassano, Patricia A., Barr, R. Graham, Rawal, Rajesh, Harris, Sarah E., Gharib, Sina A., Enroth, Stefan, Heckbert, Susan R., Lehtimäki, Terho, Gyllensten, Ulf, Gudnason, Vilmundur, Jackson, Victoria E., Tang, Wenbo, Dupuis, Josée, Soler Artigas, María, Joshi, Amit D., London, Stephanie J. and Kraft, Peter (2017) Evidence for large-scale gene-by-smoking interaction effects on pulmonary function. International Journal of Epidemiology . dyw318. ISSN 0300-5771

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Barber, Jennifer, McKeever, Tricia M., McDowell, Sarah E., Clayton, Jennifer A., Ferner, Robin E., Gordon, Richard D., Stowasser, Michael, O'Shaughnessy, Kevin M., Hall, Ian P. and Glover, Mark (2015) A systematic review and meta-analysis of thiazide-induced hyponatraemia: time to reconsider electrolyte monitoring regimens after thiazide initiation? British Journal of Clinical Pharmacology, 79 (4). pp. 566-577. ISSN 1365-2125

Barr, Helen L., Cámara, Miguel, Barrett, David, Williams, Paul, Forrester, Doug, Smyth, Alan, Honeybourne, David, Whitehouse, Joanna, Nash, Edward, Dewar, Jane, Knox, Alan and Fogarty, Andrew W. (2017) Weight gain during acute treatment of an initial pulmonary exacerbation is associated with a longer interval to the next exacerbation in adults with cystic fibrosis. ERJ Open Research, 3 (3). pp. 1-4. ISSN 2312-0541

Barr, Helen L., Halliday, Nigel, Barrett, David A., Williams, Paul, Forrester, Doug L., Peckham, Daniel, Williams, Kate, Smyth, Alan R., Honeybourne, David, Whitehouse, Joanna L., Nash, Edward F., Dewar, Jane, Clayton, Andrew, Knox, Alan J., Cámara, Miguel and Fogarty, Andrew W. (2017) Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16 (2). pp. 230-238. ISSN 1873-5010

Barskiy, Danila A., Coffey, Aaron M., Nikolaou, Panayiotis, Mikhaylov, Dmitry M., Goodson, Boyd M., Branca, Rosa T., Lu, George J., Shapiro, Mikhail G., Telkki, Ville-Veikko, Zhivonitko, Vladimir V., Koptyug, Igor V., Salnikov, Oleg G., Kovtunov, Kirill V., Bukhtiyarov, Valerii I., Rosen, Matthew S., Barlow, Michael J., Safavi, Shahideh, Hall, Ian P., Schröder, Leif and Chekmenev, Eduard Y. (2017) NMR hyperpolarization techniques of gases. Chemistry - a European Journal, 23 (4). pp. 725-751. ISSN 0947-6539

Bee, Janet, Fuller, Sharon, Miller, Suzanne and Johnson, Simon R. (2017) Lung function response and side effects to rapamycin for lymphangioleiomyomatosis: a prospective national cohort study. Thorax . ISSN 0040-6376

Blakey, John, Fearn, Andrew and Shaw, Dominick E. (2013) What drives the 'August effect'?: an observational study of the effect of junior doctor changeover on out of hours work. JRSM Short Reports, 4 (8). ISSN 2042-5333

Brand, Oliver J., Pasini, Alice, Habgood, Antony, Knox, Alan J., Jenkins, Gisli and Pang, Linhua (2016) S52 Suberanilohydroxamic acid (SAHA) inhibits collagen deposition in a transforming growth factor β1-driven precision cut lung slice (PCLS) model of pulmonary fibrosis. Thorax, 71 (Supp 3). A31. ISSN 1468-3296

Brand, Oliver J., Pasini, Alice, Habgood, Antony, Knox, Alan J., Jenkins, Gisli and Pang, Linhua (2016) Suberanilohydroxamic acid (SAHA) inhibits collagen deposition in a transforming growth factor β1-driven precision cut lung slice (PCLS) model of pulmonary fibrosis. In: British Thoracic Society Winter Meeting 2016, 7-9 Dec 2016, London, UK. (Unpublished)

Bridge, Jack Christopher, Amer, Mahetab H., Morris, Gavin E., Martin, N.R.W., Player, Darren J., Knox, Alan J., Aylott, Jonathan W., Lewis, Mark P. and Rose, Felicity R.A.J. (2018) Electrospun gelatin-based scaffolds as a novel 3D platform to study the function of contractile smooth muscle cells in vitro. Biomedical Physics & Engineering Express, 4 (4). 045039/1-045039/14. ISSN 2057-1976

Brown, Michael, Pinchin, James, Valand, Reena, Larkin, Christopher, Pattinson, Joanne, Benning, Kelly, Housley, Gemma, Hatton, Jim, Shaw, Dominick E., Syrysko, Paul, Sharples, Sarah and Blakey, John (2016) NightShift simulation to train newly qualified doctors in non-technical skills: a feasibility study. Future Hospital Journal, 3 (2). pp. 94-98. ISSN 2055-3331

Brown, Michael, Shaw, Dominick E., Sharples, Sarah, Le Jeune, Ivan and Blakey, John (2015) A survey-based cross-sectional study of doctors’ expectations and experiences of non-technical skills for out of hours work. BMJ Open, 5 (2). e006102/1-e006102/6. ISSN 2044-6055

Burkart, Kristin M., Sofer, Tamar, London, Stephanie J., Manichaikul, Ani, Hartwig, Fernando P., Yan, Qi, Artigas, María Soler, Avila, Lydiana, Chen, Wei, Thomas, Sonia Davis, Diaz, Alejandro A., Hall, Ian P., Horta, Bernardo L., Kaplan, Robert C., Laurie, Cathy C., Menezes, Ana M., Morrison, Jean V., Oelsner, Elizabeth C., Rastogi, Deepa, Rich, Stephen S., Soto-Quiros, Manuel, Stilp, Adrienne M., Tobin, Martin D., Wain, Louise V., Celedon, Juan C. and Barr, R. Graham (2018) A genome-wide association study in Hispanics/Latinos identifies novel signals for lung function: the Hispanic Community Health Study/Study of Latinos. American Journal of Respiratory and Critical Care Medicine . ISSN 1535-4970

C

Chang, William Y.C., Cane, Jennifer L., Kumaran, Maruti, Lewis, Sarah, Tattersfield, Anne E. and Johnson, Simon R. (2014) A 2-year randomised placebo-controlled trial of doxycycline for lymphangioleiomyomatosis. European Respiratory Journal, 43 (4). pp. 1114-1123. ISSN 1399-3003

Chen, Lin, Tang, Wenbo, Kowgier, Matthew, Loth, Daan W., Soler Artigas, María, Joubert, Bonnie R., Hodge, Emily, Gharib, Sina A., Smith, Albert V., Ruczinski, Ingo, Gudnason, Vilmundur, Mathias, Rasika A., Harris, Tamara B., Hansel, Nadia N., Launer, Lenore J., Barnes, Kathleen C., Hansen, Joyanna G., Albrecht, Eva, Aldrich, Melinda C., Allerhand, Michael, Barr, R. Graham, Brusselle, Guy G., Couper, David J., Curjuric, Ivan, Davies, Gail, Deary, Ian J., Dupuis, Josée, Fall, Tove, Foy, Millennia, Franceschini, Nora, Gao, Wei, Gläser, Sven, Gu, Xiangjun, Hancock, Dana B., Heinrich, Joachim, Hofman, Albert, Imboden, Medea, Ingelsson, Erik, James, Alan, Karrasch, Stefan, Koch, Beate, Kritchevsky, Stephen B., Kumar, Ashish, Lahousse, Lies, Li, Guo, Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Lohman, Kurt, Lumley, Thomas, McArdle, Wendy L., Meibohm, Bernd, Morris, Andrew P., Morrison, Alanna C., Musk, Bill, North, Kari E., Palmer, Lyle J., Probst-Hensch, Nicole M., Psaty, Bruce M., Rivadeneira, Fernando, Rotter, Jerome I., Schulz, Holger, Smith, Lewis J., Sood, Akshay, Starr, John M., Strachan, David P., Teumer, Alexander, Uitterlinden, André G., Völzke, Henry, Voorman, Arend, Wain, Louise V., Wells, Martin T., Wilk, Jemma B., Williams, O. Dale, Heckbert, Susan R., Stricker, Bruno H., London, Stephanie J., Fornage, Myriam, Tobin, Martin D., O′Connor, George T., Hall, Ian P. and Cassano, Patricia A. (2014) Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. PLoS ONE, 9 (7). e100776. ISSN 1932-6203

Clifford, R.L., Fishbane, N., Rajasekar, P., MacIsaac, J.L., McEwen, L.M., Fisher, A., Kobor, M., Knox, A.J. and Hackett, T.-L. (2017) Investigating genome wide DNA methylation in bronchial and lung fibroblasts from healthy individuals and individuals with COPD. In: American Thoracic Society 2017 International Conference, 19-24 May 2017, Washington, D.C., USA.

Clifford, Rachel L., Fishbane, N., Rajasekar, P., Fisher, A.J., Kobor, M.S., Knox, A.J. and Hackett, T.L. (2016) Investigating genome wide dna methylation in airway and parenchymal fibroblasts from healthy individuals and individuals with copd. Thorax, 71 (Suppl3). A79.1-A79. ISSN 1468-3296

Clifford, Rachel L., Fishbane, Nick, Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., Fisher, Andrew J., Brandsma, Corry-Anke, Nair, Parameswaran, Kobor, Michael S., Hackett, Tillie-Louise and Knox, Alan J. (2018) Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD. Clinical Epigenetics, 10 (1). p. 32. ISSN 1868-7083

Clifford, Rachel L., Jones, Meaghan J., MacIsaac, Julia L., McEwen, Lisa M., Goodman, Sarah J., Mostafavi, Sara, Kobor, Michael S. and Carlsten, Chris (2017) Inhalation of diesel exhaust and allergen alters human bronchial epithelium DNA methylation. Journal of Allergy and Clinical Immunology, 139 (1). pp. 112-121. ISSN 1097-6825

Clifford, Rachel L., Patel, J.K., Shaw, D.E., Knox, A.J. and Kobor, M.S. (2016) Investigating genome wide dna methylation in airway smooth muscle cells from asthmatic and non-asthmatic donors. Thorax, 71 (Suppl3). A215.2-A216. ISSN 1468-3296

Coward, William R., Brand, Oliver J., Pasini, Alice, Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2017) Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology . ISSN 1535-4989

Coward, William R., Feghali-Bostwick, Carol A., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2014) A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis. FASEB Journal, 28 (7). pp. 3183-3196. ISSN 0892-6638

D

Deacon, Karl and Knox, Alan J. (2018) PINX1 and TERT are required for TNF-α-induced airway smooth muscle chemokine gene expression. Journal of Immunology, 200 (4). pp. 1283-1294. ISSN 1550-6606

Donaldson, J.W., McKeever, Tricia M., Hall, Ian P., Hubbard, R.B. and Fogarty, Andrew W. (2014) The UK prevalence of hereditary haemorrhagic telangiectasia and its association with sex, socioeconomic status and region of residence: a population-based study. Thorax, 69 (2). pp. 161-167. ISSN 1468-3296

Dongre, Arundhati, Clements, Debbie, Fisher, Andrew J. and Johnson, Simon R. (2017) Cathepsin K in lymphangioleiomyomatosis: LAM cell-fibroblast Interactions enhance protease activity by extracellular acidification. American Journal of Pathology, 187 (8). pp. 1750-1762. ISSN 1525-2191

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Forrester, D.L., Barr, Helen L., Fogarty, Andrew W. and Knox, A. (2017) sTREM-1 is elevated in cystic fibrosis and correlates with proteases. Pediatric Pulmonology, 52 (4). pp. 467-471. ISSN 1099-0496

Forrester, Doug L., Knox, Alan J., Smyth, Alan R., Barr, Helen L., Simms, Rebecca, Pacey, Sarah J., Pavord, Ian D., Honeybourne, David, Dewar, Jane, Clayton, Andy and Fogarty, Andrew W. (2015) Glutamine supplementation in cystic fibrosis: a randomized placebo-controlled trial. Pediatric Pulmonology, 51 (3). pp. 253-257. ISSN 1099-0496

Forrester, Doug L., Knox, Alan J., Smyth, Alan R. and Fogarty, Andrew W. (2013) Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study. Journal of Cystic Fibrosis, 12 (3). pp. 284-289. ISSN 1873-5010

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Gharib, Sina A., Loth, Daan W., Soler Artigas, María, Birkland, Timothy P., Wilk, Jemma B., Wain, Louise V., Brody, Jennifer A., Obeidat, Ma'en, Hancock, Dana B., Tang, Wenbo, Rawal, Rajesh, Boezen, H. Marike, Imboden, Medea, Huffman, Jennifer E., Lahousse, Lies, Alves, Alexessander C., Manichaikul, Ani, Hui, Jennie, Morrison, Alanna C., Ramasamy, Adaikalavan, Smith, Albert Vernon, Gudnason, Vilmundur, Surakka, Ida, Vitart, Veronique, Evans, David M., Strachan, David P., Deary, Ian J., Hofman, Albert, Gläser, Sven, Wilson, James F., North, Kari E., Zhao, Jing Hua, Heckbert, Susan R., Jarvis, Deborah L., Probst-Hensch, Nicole, Schulz, Holger, Barr, R. Graham, Jarvelin, Marjo-Riitta, O'Connor, George T., Kähönen, Mika, Cassano, Patricia A., Hysi, Pirro G., Dupuis, Josée, Hayward, Caroline, Psaty, Bruce M., Hall, Ian P., Parks, William C., Tobin, Martin D. and London, Stephanie J. (2015) Integrative pathway genomics of lung function and airflow obstruction. Human Molecular Genetics, 24 (23). pp. 6836-6848. ISSN 1460-2083

Gill, Dipender, Sheehan, Nuala A., Wielscher, Matthias, Shrine, Nick, Amaral, Andre F. S., Thompson, John R., Granell, Raquel, Leynaert, Bénédicte, Real, Francisco Gómez, Hall, Ian P., Tobin, Martin D., Auvinen, Juha, Ring, Susan M., Jarvelin, Marjo-Riitta, Wain, Louise V., Henderson, John, Jarvis, Deborah and Minelli, Cosetta (2017) Age at menarche and lung function: a Mendelian randomization study. European Journal of Epidemiology . ISSN 0393-2990

H

Habgood, Antony, Tatler, Amanda L., Porte, Joanne, Wahl, Sharon, M., Laurent, Geoffrey, J., John, Alison, E., Johnson, Simon, R. and Jenkins, Gisli (2016) Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis. Laboratory Investigation . ISSN 1530-0307

Hakamy, Ali, Bolton, Charlotte E., Gibson, Jack E. and McKeever, Tricia M. (2018) Risk of fall in patients with COPD. Thorax . ISSN 1468-3296

Hakamy, Ali, Bolton, Charlotte E. and McKeever, Tricia M. (2017) The effect of pulmonary rehabilitation on mortality, balance, and risk of fall in stable patients with chronic obstructive pulmonary disease: a systematic review. Chronic Respiratory Disease, 14 (1). pp. 54-62. ISSN 1479-9731

Hakamy, Ali, McKeever, Tricia M., Gibson, Jack E. and Bolton, Charlotte E. (2017) The recording and characteristics of pulmonary rehabilitation in patients with COPD using The Health Information Network (THIN) primary care database. npj Primary Care Respiratory Medicine, 27 (1). 58/1-58/7. ISSN 2055-1010

Hakamy, Ali, McKeever, Tricia M., Steiner, Michael C., Roberts, C. Michael, Singh, Sally J. and Bolton, Charlotte E. (2017) The use of the practice walk test in pulmonary rehabilitation program: National COPD Audit Pulmonary Rehabilitation Workstream. International Journal of Chronic Obstructive Pulmonary Disease, 12 . pp. 2681-2686. ISSN 1176-9106

Hall, Ian P., Fowler, Andrew V., Gupta, Abhya, Tetzlaff, Kay, Nivens, Michael C., Sarno, Maria, Finnigan, Helen A., Bateman, Eric D. and Rand Sutherland, E. (2015) Efficacy of BI 671800, an oral CRTH2 antagonist, in poorly controlled asthma as sole controller and in the presence of inhaled corticosteroid treatment. Pulmonary Pharmacology & Therapeutics, 32 . pp. 37-44. ISSN 1094-5539

Hanratty, Catherine E., Matthews, John G., Arron, Joseph R., Choy, David F., Pavord, Ian D., Bradding, P., Brightling, Christopher E., Chaudhuri, Rekha, Cowan, Douglas C., Djukanovic, Ratko, Gallagher, Nicola, Fowler, Stephen J., Hardman, Tim C., Harrison, Tim, Holweg, Cécile T., Howarth, Peter H., Lordan, James, Mansur, Adel H., Menzies-Gow, Andrew, Mosesova, Sofia, Niven, Robert M., Robinson, Douglas S., Shaw, Dominick E., Walker, Samantha, Woodcock, Ashley and Heaney, Liam G. (2018) A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial. Trials, 19 . p. 5. ISSN 1745-6215

Hekking, Pieter-Paul, Loza, Matt J., Pavlidis, Stelios, de Meulder, Bertrand, Lefaudeux, Diane, Baribaud, Fred, Auffray, Charles, Wagener, Ariane H., Brinkman, Paul, Lutter, Rene, Bansal, Aruna T., Sousa, Ana R., Bates, Steve A., Pandis, Yannis, Fleming, Louise J., Shaw, Dominique E., Fowler, Stephen J., Guo, Y., Meiser, Andrea, Sun, Kai, Corfield, Julie, Howarth, Peter H., Bel, Elisabeth H., Adcock, Ian M., Chung, Kian Fan, Djukanovic, Ratko and Sterk, Peter J. (2018) Pathway discovery using transcriptomic profiles in adult-onset severe asthma. Journal of Allergy and Clinical Immunology, 141 (4). pp. 1280-1290. ISSN 0091-6749

Hekking, Pieter-Paul, Loza, Matthew J., Pavlidis, Stelios, De Meulder, Bertrand, Lefaudeux, Diane, Baribaud, Frederic, Auffray, Charles, Wagener, Ariane H., Brinkman, Paul, Lutter, René, Bansal, Aruna T., Sousa, Ana R., Bates, Stewart A., Pandis, Ioannis, Fleming, Louise J., Shaw, Dominick E., Fowler, Stephen J., Guo, Yike, Meiser, Andrea, Sun, Kai, Corfield, Julie, Howarth, Peter, Bel, Elisabeth H., Adcock, Ian M., Chung, Kian Fan, Djukanovic, Ratko and Sterk, Peter J. (2017) Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma. European Respiratory Journal, 50 (3). p. 1602298. ISSN 1399-3003

Hill, Michael, Philp, Christopher J., Billington, Charlotte K., Tatler, Amanda L., Johnson, Simon R., O'Dea, Reuben D. and Brook, Bindi S. (2018) A theoretical model of inflammation- and mechanotransduction- driven asthmatic airway remodelling. Biomechanics and Modeling in Mechanobiology . ISSN 1617-7940

Hobbs, Brian D., de Jong, Kim, Lamontagne, Maxime, Bossé, Yohan, Shrine, Nick, Artigas, María Soler, Wain, Louise V., Hall, Ian P., Jackson, Victoria E., Wyss, Annah B., London, Stephanie J., North, Kari E., Franceschini, Nora, Strachan, David P., Beaty, Terri H., Hokanson, John E., Crapo, James D., Castaldi, Peter J., Chase, Robert P., Bartz, Traci M., Heckbert, Susan R., Psaty, Bruce M., Gharib, Sina A., Zanen, Pieter, Lammers, Jan W., Oudkerk, Matthijs, Groen, H.J., Locantore, Nicholas, Tal-Singer, Ruth, Rennard, Stephen I., Vestbo, Jørgen, Timens, Wim, Paré, Peter D., Latourelle, Jeanne C., Dupuis, Josée, O'Connor, George T., Wilk, Jemma B., Kim, Woo Jin, Lee, Mi Kyeong, Oh, Yeon-Mok, Vonk, Judith M., de Koning, Harry J., Leng, Shuguang, Belinsky, Steven A., Tesfaigzi, Yohannes, Manichaikul, Ani, Wang, Xin-Qun, Rich, Stephen S., Barr, R. Graham, Sparrow, David, Litonjua, Augusto A., Bakke, Per, Gulsvik, Amund, Lahousse, Lies, Brusselle, Guy G., Stricker, Bruno H., Uitterlinden, André G., Ampleford, Elizabeth J., Bleecker, Eugene R., Woodruff, Prescott G., Meyers, Deborah A., Qiao, Dandi, Lomas, David A., Yim, Jae-Joon, Kim, Deog Kyeom, Hawrylkiewicz, Iwona, Sliwinski, Pawel, Hardin, Megan, Fingerlin, Tasha E., Schwartz, David A., Postma, Dirkje S., MacNee, William, Tobin, Martin D., Silverman, Edwin K., Boezen, H. Marike and Cho, Michael H. (2017) Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis. Nature Genetics, 49 (3). pp. 426-432. ISSN 1546-1718

Hodgson, David, Anderson, John, Reynolds, Catherine, Meakin, Garry, Bailey, Helen, Pavord, Ian, Shaw, Dominick E. and Harrison, Timothy W. (2015) A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA). Thorax, 70 (6). pp. 559-565. ISSN 1468-3296

Housley, Gemma, Lewis, Sarah, Usman, Adeela, Gordon, Adam L. and Shaw, Dominick E. (2017) Accurate identification of hospital admissions from care homes; development and validation of an automated algorithm. Age and Ageing . ISSN 0002-0729

Howard, Sam, Lang, Alexandra, Patel, Mitesh Dilipkumar Kantilal, Sharples, Sarah and Shaw, Dominick E. (2014) Electronic monitoring of adherence to inhaled medication in asthma. Current Respiratory Medicine Reviews, 10 (1). pp. 50-63. ISSN 1875-6387

Howard, Sam, Lang, Alexandra. R., Sharples, Sarah and Shaw, Dominick E. (2016) What are the pros and cons of electronically monitoring inhaler use in asthma?: a multistakeholder perspective. BMJ Open Respiratory Research, 3 (1). e000159/1-e000159/10. ISSN 2052-4439

Howard, Sam, Lang, Alexandra. R., Sharples, Sarah and Shaw, Dominick E. (2016) See I told you I was taking it! - attitudes of adolescents with asthma towards a device monitoring their inhaler use: Implications for future design. Applied Ergonomics . ISSN 0003-6870 (In Press)

Htwe, Su S., Cha, Byung H., Yue, Kan, Khademhosseini, Ali, Knox, Alan J. and Ghaemmaghami, Amir M. (2017) Role of ROCK isoforms in regulation of stiffness induced myofibroblast differentiation in lung fibrosis. American Journal of Respiratory Cell and Molecular Biology, 56 (6). ISSN 1535-4989

Hughes-Riley, Theodore, Six, Joseph S., Lilburn, D.M.L., Stupic, Karl F., Dorkes, Alan C., Shaw, Dominick E., Pavlovskaya, Galina E. and Meersmann, Thomas (2013) Cryogenics free production of hyperpolarized 129Xe and 83Kr for biomedical MRI applications. Journal of Magnetic Resonance, 237 . pp. 23-33. ISSN 1096-0856

I

Ierodiakonou, Despo, Portelli, Michael A., Postma, Dirkje S., Koppelman, Gerard H., Gerritsen, Jorrit, ten Hacken, Nick H.T., Timens, Wim, Boezen, H. Marike, Vonk, Judith M. and Sayers, Ian (2016) Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma. European Respiratory Journal, 47 (5). pp. 1568-1571. ISSN 1399-3003

J

Jackson, Victoria E., Ntalla, Ioanna, Sayers, Ian, Morris, Richard, Whincup, Peter, Casas, Juan-Pablo, Amuzu, Antoinette, Choi, Minkyoung, Dale, Caroline, Kumari, Meena, Engmann, Jorgen, Kalsheker, Noor, Chappell, Sally, Guetta-Baranes, Tamar, McKeever, Tricia M., Palmer, Colin N.A., Tavendale, Roger, Holloway, John W., Sayer, Avan A., Dennison, Elaine M., Cooper, Cyrus, Bafadhel, Mona, Barker, Bethan, Brightling, Chris, Bolton, Charlotte E., John, Michelle E., Parker, Stuart G., Moffat, Miriam F., Wardlaw, Andrew J., Connolly, Martin J., Porteous, David J., Smith, Blair H., Padmanabhan, Sandosh, Hocking, Lynne, Stirrups, Kathleen E., Deloukas, Panos, Strachan, David P., Hall, Ian P., Tobin, Martin D. and Wain, Louise V. (2016) Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. Thorax, 71 (6). pp. 501-509. ISSN 1468-3296

Jenkins, R. Gisli, Simpson, Juliet K., Saini, Gauri, Bentley, Jane H., Russell, Anne-Marie, Braybrooke, Rebecca, Molyneux, Philip L., McKeever, Tricia M., Wells, Athol U., Flynn, Aiden, Hubbard, Richard B., Leeming, Diana J., Marshall, Richard P., Karsdal, Morten A., Lukey, Pauline T. and Maher, Toby M. (2015) Longitudinal change in collagen degradation biomarkers in idiopathic pulmonary fibrosis: an analysis from the prospective, multicentre PROFILE study. Lancet Respiratory Medicine, 3 (6). pp. 462-472. ISSN 2213-2619

Jevnikar, Zala, Östling, Jörgen, Ax, Elisabeth, Calvén, Jenny, Thörn, Kristofer, Israelsson, Elisabeth, Öberg, Lisa, Singhania, Akul, Lau, Laurie C.K., Wilson, Susan J., Ward, Jonathan A., Chauhan, Anoop, Sousa, Ana R., De Meulder, Bertrand, Loza, Matthew J., Baribaud, Frédéric, Sterk, Peter J., Chung, Kian Fan, Sun, Kai, Guo, Yike, Adcock, Ian M., Payne, Debbie, Dahlen, Barbro, Chanez, Pascal, Shaw, Dominick E., Krug, Norbert, Hohlfeld, Jens M., Sandström, Thomas, Djukanovic, Ratko, James, Anna, Hinks, Timothy S.C., Howarth, Peter H., Vaarala, Outi, van Geest, Marleen and Olsson, Henric K. (2018) Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of Allergy and Clinical Immunology . ISSN 0091-6749

Jin, Chunyu, Langston, Paul A., Pavlovskaya, Galina E., Hall, Mattew R. and Rigby, Sean P. (2016) Statistics of highly heterogeneous flow fields confined to three-dimensional random porous media. Physical Review E, 93 . 013122/1-013122/10. ISSN 1550-2376

John, A.E., Wilson, M.R., Habgood, A., Porte, J., Tatler, A.L., Stavrou, A, Miele, G, Jolly, L, Knox, A.J., Takata, M, Offermanns, S and Jenkins, R.G. (2016) Loss of epithelial Gq and G11 signaling inhibits TGFbeta production but promotes IL-33-mediated macrophage polarization and emphysema. Science Signalling, 9 (451). ra104. ISSN 1945-0877

John, Alison, E., Wilson, Michael, R., Habgood, Anthony, Porte, Joanne, Tatler, Amanda L., Stavrou, Anastasios, Miele, Gino, Jolly, Lisa, Knox, Alan J., Takata, Masao, Offermanns, Stefan and Jenkins, R. Gisli (2016) Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema. Science Signaling, 9 (451). ra104/1. ISSN 1937-9145

John, Catherine, Soler Artigas, María, Hui, Jennie, Nielsen, Sune Fallgaard, Rafaels, Nicholas, Paré, Peter D, Hansel, Nadia N., Shrine, Nick, Kilty, Iain, Malarstig, Anders, Jelinsky, Scott A, Vedel-Krogh, Signe, Barnes, Kathleen, Hall, Ian P., Beilby, John, Musk, Arthur W., Nordestgaard, Børge G., James, Alan, Wain, Louise V. and Tobin, Martin D. (2017) Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline. Thorax, 72 (5). pp. 400-408. ISSN 1468-3296

John, Michelle, Cockcroft, John R., McKeever, Tricia M., Coward, William R., Shale, Dennis J., Johnson, Simon R., Thornton, Jim, Harrison, Timothy W., Knox, Alan J. and Bolton, Charlotte E. (2015) Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. International Journal of Chronic Obstructive Pulmonary Disease, 10 (1). pp. 211-221. ISSN 1178-2005

John, Michelle, Hussain, Samia, Prayle, Andrew, Simms, Rebecca, Cockroft, John R. and Bolton, Charlotte E. (2013) Target renal damage: the microvascular associations of increased aortic stiffness in patients with COPD. Respiratory Research, 14 (31). pp. 1-7. ISSN 1465-9921

John, Michelle, McKeever, Tricia M., Haddad, Maath Al, Hall, Ian P., Sayers, Ian, Cockcroft, John R. and Bolton, Charlotte E. (2016) Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease. Chronic Respiratory Disease, 13 (3). pp. 247-255. ISSN 1479-9731

Johnson, Sebastian L., Szigeti, Matyas, Cross, Mary, Brightling, Christopher, Chaudhuri, R., Harrison, Timothy W., Mansur, Adel, Robison, Laura, Sattar, Zahid, Jackson, David, Mallia, Patrick, Wong, Ernie, Corrigan, Christopher, Higgins, Bernhard, Ind, Philip, Singh, Dave, Thomson, Neil C., Ashby, Deborah and Chauhan, Anoop (2016) Azithromycin for Acute Exacerbations of Asthma: the AZALEA randomized clinical trial. JAMA Internal Medicine, 176 (11). pp. 1630-1637. ISSN 2168-6114

K

Kaczmarek, K.A., Clifford, R.L., Patel, J.K., Shaw, D., Dowden, J. and Knox, A.L. (2017) The role of histone arginine methylation in gene expression of airway smooth muscle cells in asthma. In: American Thoracic Society 2017 International Conference, 19-24 May 2017, Washington, D.C., USA.

Kaczmarek, K.A., Clifford, Rachel L., Patel, J.K., Shaw, D.E., Dowden, J. and Knox, A.J. (2016) The role of histone arginine methylation in gene expression of airway smooth muscle cells in asthma. Thorax, 71 (Suppl3). A214.3-A215. ISSN 1468-3296

Ketelaar, M.E., Nawijn, Martijn C., Shaw, Dominick E., Koppelman, Gerard H. and Sayers, Ian (2016) The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma. Clinical & Experimental Allergy, 46 (6). pp. 884-887. ISSN 1365-2222

Khakwani, Aamir, Rich, Anna L., Tata, Laila J., Powell, Helen A., Stanley, Rosamund A., Baldwin, David R. and Hubbard, Richard B. (2014) Small-cell lung cancer in England: trends in survival and chemotherapy using the National Lung Cancer Audit. PLoS ONE, 9 (2). e89426. ISSN 1932-6203

Kheirallah, Alexander K., Miller, Suzanne, Hall, Ian P. and Sayers, Ian (2016) Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology. Advances in Genetics, 93 . pp. 57-145. ISSN 0065-2660

Kheirallah, Alexander K., de Moor, Cornelia H., Faiz, Alen, Sayers, Ian and Hall, Ian P. (2017) Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways. BMC Genomics, 18 (1). p. 248. ISSN 1471-2164

Khuo, Chih-Hsi Scott, Pavlidis, Stelios, Loza, Matthew, Baribaud, Fred, Rowe, Anthony, Pandis, Ioannis, Hoda, Uruj, Rossios, Christos, Sousa, Ana, Wilson, Susan J., Howarth, Peter, Dahlen, Barbro, Dahlen, Sven-Erik, Chanez, Pascal, Shaw, Dominick E., Krug, Norbert, Sandström, Thomas, De Meulder, Betrand, Lefaudeux, Diane, Fowler, Stephen, Fleming, Louise, Corfield, Julie, Auffray, Charles, Sterk, Peter J., Djukanovic, Ratko, Guo, Yike, Adcock, Ian M. and Chung, Kian Fan (2016) A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED. American Journal of Respiratory and Critical Care Medicine . ISSN 1535-4970

Koning, Henk, Oosterhout, Antoon J.M. van, Brouwer, Uilke, Boef, Lisette E. den, Gras, Renée, Reinders-Luinge, Marjan, Brandsma, Corry-Anke, Toorn, Marco van der, Hylkema, Machteld N., Willemse, Brigitte W.M., Sayers, Ian, Koppelman, Gerard H. and Nawijn, Martijn C. (2014) Mouse Protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo. PLoS ONE, 9 (7). e98197/1-e98197/10. ISSN 1932-6203

L

Lefaudeux, Diane, De Meulder, Bertrand, Loza, Matthew J., Peffer, Nancy, Rowe, Anthony, Baribaud, Frédéric, Bansal, Aruna T., Lutter, Rene, Sousa, Ana R., Corfield, Julie, Pandis, Ioannis, Bakke, Per S., Caruso, Massimo, Chanez, Pascal, Dahlén, Sven-Erik, Fleming, Louise J., Fowler, Stephen J., Horvath, Ildiko, Krug, Norbert, Montuschi, Paolo, Sanak, Marek, Sandstrom, Thomas, Shaw, Dominic E., Singer, Florian, Sterk, Peter J., Roberts, Graham, Adcock, Ian M., Djukanovic, Ratko, Auffray, Charles and Chung, Kian Fan (2017) U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics. Journal of Allergy and Clinical Immunology, 139 (6). pp. 1797-1807. ISSN 0091-6749

Leroyer, Christophe, Anderson, J.R., Mortimer, K., Pang, L., Smith, K.M., Bailey, H., Hodgson, D.B., Shaw, Dominick E., Knox, A.J. and Harrison, Timothy W. (2016) Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial. PLoS ONE, 11 (8). e0160257. ISSN 1932-6203

Lilburn, David M.L., Lesbats, Clémentine, Six, Joseph S., Dubuis, Eric, Yew-Booth, Liang, Shaw, Dominick E., Belvisi, Maria G., Birrell, Mark A., Pavlovskaya, Galina E. and Meersmann, Thomas (2015) Hyperpolarized 83Kr magnetic resonance imaging of alveolar degradation in a rat model of emphysema. Journal of the Royal Society Interface, 12 (107). 20150192/1-20150192/12. ISSN 1742-5689

Lilburn, David M.L., Tatler, Amanda L., Six, Joseph S., Lesbats, Clémentine, Habgood, Antony, Porte, Joanne, Hughes-Riley, Theodore, Shaw, Dominick E., Jenkins, Gisli and Meersmann, Thomas (2015) Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma. Magnetic Resonance in Medicine . ISSN 1522-2594

Liu, Bo, Billington, Charlotte K., Henry, Amanda P., Bhaker, Sangita K., Kheirallah, Alexander K., Swan, Caroline and Hall, Ian P. (2018) Chloride intracellular channel 1 (CLIC1) contributes to modulation of cyclic AMP-activated whole cell chloride currents in human bronchial epithelial cells. Physiological Reports, 6 (2). e13508. ISSN 2051-817X

Loth, Daan W., Artigas, María Soler, Gharib, Sina A., Wain, Louise V., Franceschini, Nora, Koch, Beate, Pottinger, Tess D., Smith, Albert Vernon, Duan, Qing, Oldmeadow, Chris, Lee, Mi Kyeong, Strachan, David P., James, Alan L., Huffman, Jennifer E., Vitart, Veronique, Ramasamy, Adaikalavan, Wareham, Nicholas J., Kaprio, Jaakko, Wang, Xin-Qun, Trochet, Holly, Kähönen, Mika, Flexeder, Claudia, Albrecht, Eva, Lopez, Lorna M., de Jong, Kim, Thyagarajan, Bharat, Alves, Alexessander Couto, Enroth, Stefan, Omenaas, Ernst, Joshi, Peter K., Fall, Tove, Viñuela, Ana, Launer, Lenore J., Loehr, Laura R., Fornage, Myriam, Li, Guo, Wilk, Jemma B., Tang, Wenbo, Manichaikul, Ani, Lahousse, Lies, Harris, Tamara B., North, Kari E., Rudnicka, Alicja R., Hui, Jennie, Gu, Xiangjun, Lumley, Thomas, Wright, Alan F., Hastie, Nicholas D., Campbell, Susan, Kumar, Rajesh, Pin, Isabelle, Scott, Robert A., Pietiläinen, Kirsi H., Surakka, Ida, Liu, Yongmei, Holliday, Elizabeth G., Schulz, Holger, Heinrich, Joachim, Davies, Gail, Vonk, Judith M., Wojczynski, Mary, Pouta, Anneli, Johansson, Åsa, Wild, Sarah H., Ingelsson, Erik, Rivadeneira, Fernando, Völzke, Henry, Hysi, Pirro G., Eiriksdottir, Gudny, Morrison, Alanna C., Rotter, Jerome I., Gao, Wei, Postma, Dirkje S., White, Wendy B., Rich, Stephen S., Hofman, Albert, Aspelund, Thor, Couper, David, Smith, Lewis J., Psaty, Bruce M., Lohman, Kurt, Burchard, Esteban G., Uitterlinden, André G., Garcia, Melissa, Joubert, Bonnie R., McArdle, Wendy L., Musk, A Bill, Hansel, Nadia, Heckbert, Susan R., Zgaga, Lina, van Meurs, Joyce B.J., Navarro, Pau, Rudan, Igor, Oh, Yeon-Mok, Redline, Susan, Jarvis, Deborah L., Zhao, Jing Hua, Rantanen, Taina, O'Connor, George T., Ripatti, Samuli, Scott, Rodney J., Karrasch, Stefan, Grallert, Harald, Gaddis, Nathan C., Starr, John M., Wijmenga, Cisca, Minster, Ryan L., Lederer, David J., Pekkanen, Juha, Gyllensten, Ulf, Campbell, Harry, Morris, Andrew P., Gläser, Sven, Hammond, Christopher J., Burkart, Kristin M, Beilby, John, Kritchevsky, Stephen B., Gudnason, Vilmundur, Hancock, Dana B., Williams, O Dale, Polasek, Ozren, Zemunik, Tatijana, Kolcic, Ivana, Petrini, Marcy F., Wjst, Matthias, Kim, Woo Jin, Porteous, David J., Smith, Blair H., Viljanen, Anne, Heliövaara, Markku, Attia, John R., Sayers, Ian, Hampel, Regina, Gieger, Christian, Deary, Ian J, Boezen, H. Marike, Newman, Anne, Jarvelin, Marjo-Riitta, Wilson, James F, Lind, Lars, Stricker, Bruno H., Teumer, Alexander, Spector, Timothy D., Melén, Erik, Peters, Marjolein J., Lange, Leslie A., Barr, R. Graham, Bracke, Ken R., Verhamme, Fien M., Sung, Joohon, Hiemstra, Pieter S., Cassano, Patricia A., Sood, Akshay, Hayward, Caroline, Dupuis, Josée, Hall, Ian P., Brusselle, Guy G., Tobin, Martin D. and London, Stephanie J. (2014) Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics, 46 (7). pp. 669-677. ISSN 1546-1718

M

Maher, Toby M., Oballa, Eunice, Simpson, Juliet K., Porte, Joanne, Habgood, Anthony, Fahy, William A, Flynn, Aiden, Molyneux, Philip L., Braybrooke, Rebecca, Divyateja, Hrushikesh, Parfrey, Helen, Rassl, Doris, Russell, Anne-Marie, Hubbard, Richard, Wells, Athol U, Lukey, Pauline T., Marshall, Richard P. and Jenkins, R. Gisli (2017) An epithelial biomarker signature for idiopathic pulmonary fibrosis: an analysis from the multicentre PROFILE cohort study. Lancet Respiratory Medicine, 5 (12). pp. 946-955. ISSN 2213-2619

Malkar, Aditya, Wilson, Emma, Harrison, Timothy W., Shaw, Dominick E. and Creaser, Colin (2016) Untargeted metabolic profiling of saliva by liquid chromatography-mass spectrometry for the identification of potential diagnostic biomarkers of asthma. Analytical Methods, 8 (27). pp. 5407-5413. ISSN 1759-9679

Matthey, Michaela, Roberts, Richard, Seidinger, Alexander, Simon, Annika, Schröder, Ralf, Kuschak, Markus, Annala, Suvi, König, Gabriele M., Müller, Christa E., Hall, Ian P., Kostenis, Evi and Wenzel, Daniela (2017) Targeted inhibition of Gq signaling induces airway relaxation in mouse models of asthma. Science Translational Medicine, 9 (407). ISSN 1946-6242

McKeever, Tricia, Mortimer, Kevin, Wilson, Andrew, Walker, Samantha, Brightling, Christopher, Skeggs, Andrew, Pavord, Ian, Price, David, Duley, Lelia, Thomas, Mike, Bradshaw, Lucy, Higgins, Bernard, Haydock, Rebecca, Mitchell, Eleanor, Devereux, Graham and Harrison, Timothy (2018) Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations. New England Journal of Medicine, 378 (10). pp. 902-910. ISSN 1533-4406

McKeever, Tricia M., Harrison, Timothy W., Hubbard, Richard and Shaw, Dominick E. (2013) Inhaled corticosteroids and the risk of pneumonia in people with asthma. Chest, 144 (6). pp. 1788-1794. ISSN 1931-3543

McKeever, Tricia M., Hearson, Glenn, Housley, Gemma, Reynolds, Catherine, Kinnear, William, Harrison, Timothy W., Kelly, Anne-Maree and Shaw, Dominick E. (2016) Using venous blood gas analysis in the assessment of COPD exacerbations: a prospective cohort study. Thorax, 71 (3). pp. 210-215. ISSN 1468-3296

Metelkina, Olga N., Lodge, R.W., Rudakovskaya, Polina G., Gerasimov, Vasiliy M., Lucas, Carlos H., Grebennikov, Ivan S., Shchetinin, Igor V., Savchenko, Alexander G., Pavlovskaya, Galina E., Rance, Graham A., Gimenez-Lopez, Maria del Carmen, Khlobystov, Andrei N. and Majouga, Alexander G. (2017) Nanoscale engineering of hybrid magnetite–carbon nanofibre materials for magnetic resonance imaging contrast agents. Journal of Materials Chemistry C, 5 . pp. 2167-2174. ISSN 2050-7496

Miller, Suzanne, Coveney, Claire, Johnson, Janice, Farmaki, Aliki-Eleni, Gupta, Nishant, Tobin, Martin D., Wain, Louise V., McCormack, Francis, Boocock, David J. and Johnson, Simon R. (2018) The vitamin D binding protein axis modifies disease severity in Lymphangioleiomyomatosis. European Respiratory Journal . ISSN 1399-3003 (In Press)

Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P. and Sayers, Ian (2016) The Ser82 RAGE variant affects lung function and serum RAGE in smokers and sRAGE production in vitro. PLoS ONE, 11 (10). e0164041/1-e0164041/16. ISSN 1932-6203

Miller, Suzanne, Melén, Erik, Merid, S. K., Hall, Ian P. and Sayers, Ian (2016) Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development. Respiratory Research, 17 (95). ISSN 1465-993X

Mohan, Divya, Forman, Julia R., Allinder, Matthew, McEniery, Carmel M., Bolton, Charlotte Emma, Cockcroft, John R., MacNee, William, Fuld, Jonathan, Marchong, Mellone, Gale, Nichola Sian, Fisk, Marie, Nagarajan, Sridevi, Cheriyan, Joseph, Lomas, David A., Calverley, Peter M.A., Miller, Bruce E., Tal-Singer, Ruth, Wilkinson, Ian B. and Polkey,, Michael I. (2018) Fibrinogen does not relate to cardiovascular or muscle manifestations in COPD: cross-sectional data from the ERICA study. Thorax . ISSN 1468-3296

Morris, G.E., Bridge, J.C., Brace, L.A., Knox, A.J., Aylott, Jonathan W., Brightling, C.E., Ghaemmaghami, Amir M. and Rose, Felicity R.A.J. (2014) A novel electrospun biphasic scaffold provides optimal three-dimensional topography forin vitroco-culture of airway epithelial and fibroblast cells. Biofabrication, 6 (3). 035014/1-035014/14. ISSN 1758-5090

Morris, G.E., Bridge, J.C., Eltboli, O.M.I., Lewis, M.P., Knox, A.J., Aylott, Jonathan W., Brightling, C.E., Ghaemmaghami, A.M. and Rose, Felicity R.A.J. (2014) Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds. American Journal of Physiology - Lung Cellular and Molecular Physiology, 307 (1). L38-L47. ISSN 1522-1504

N

Nadal, Jodie, Channavajjhala, Sarath K., Jia, Wenjing, Clayton, Jenny, Hall, Ian P. and Glover, Mark (2018) Clinical and molecular features of thiazide-induced hyponatremia. Current Hypertension Reports, 20 (4). 31/1-31/7. ISSN 1534-3111

Navaratnam, Vidya, Millett, Elizabeth R.C., Hurst, John R., Thomas, Sara L., Smeeth, Liam, Hubbard, Richard B., Brown, Jeremy and Quint, Jennifer K. (2016) Bronchiectasis and the risk of cardiovascular disease: a population-based study. Thorax, 72 (2). pp. 161-166. ISSN 1468-3296

Naveed, Shams-un-nisa, Clements, Debbie, Jackson, David J., Philp, Christopher, Billington, Charlotte K., Soomro, Irshad N., Reynolds, Catherine, Harrison, Timothy W., Johnston, Sebastian L., Shaw, Dominick E. and Johnson, Simon R. (2017) MMP-1 activation contributes to airway smooth muscle growth and asthma severity. American Journal of Respiratory and Critical Care Medicine, 195 (8). pp. 1000-1009. ISSN 1535-4970

O

O'Dowd, Emma L., McKeever, Tricia M., Baldwin, David R., Anwar, Sadia, Powell, Helen A., Gibson, Jack E., Iyen-Omofoman, Barbara and Hubbard, Richard B. (2015) What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK? Thorax, 70 (2). pp. 161-168. ISSN 1468-3296

Obeidat, Ma'en, Hao, Ke, Bossé, Yohan, Nickle, David C., Nie, Yunlong, Postma, Dirkje S., Laviolette, Michel, Sandford, Andrew J., Daley, Denise D., Hogg, James C., Elliott, W. Mark, Fishbane, Nick, Timens, Wim, Hysi, Pirro G., Kaprio, Jaakko, Wilson, James F., Hui, Jennie, Rawal, Rajesh, Schulz, Holger, Stubbe, Beate, Hayward, Caroline, Polasek, Ozren, Järvelin, Marjo-Riitta, Zhao, Jing Hua, Jarvis, Deborah, Kähönen, Mika, Franceschini, Nora, North, Kari E., Loth, Daan W., Brusselle, Guy G., Smith, Albert Vernon, Gudnason, Vilmundur, Bartz, Traci M, Wilk, Jemma B., O'Connor, George T., Cassano, Patricia A., Tang, Wenbo, Wain, Louise V., Artigas, María Soler, Gharib, Sina A., Strachan, David P., Sin, Don D., Tobin, Martin D., London, Stephanie J., Hall, Ian P. and Paré, Peter D. (2015) Molecular mechanisms underlying variations in lung function: a systems genetics analysis. Lancet Respiratory Medicine, 3 (10). pp. 782-795. ISSN 2213-2619

Osman, Gizem, Rodriguez, Jason, Chan, Sze Yan, Chisholm, Jane, Duncan, Gregg, Kim, Namho, Tatler, Amanda L., Shakesheff, Kevin M., Hanes, Justin, Suk, Jung Soo and Dixon, James E. (2018) PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy. Journal of Controlled Release, 285 . pp. 35-45. ISSN 1873-4995

P

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2018) Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1861 (5). pp. 463-472. ISSN 0006-3002

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2016) Effect of epigenetic inhibitors on lung fibroblast phenotype change in idiopathic pulmonary fibrosis. Thorax, 71 (Supp3). A32. ISSN 1468-3296

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2016) Effect of epigenetic inhibitors on lung fibroblast phenotype change in idiopathic pulmonary fibrosis. In: British Thoracic Society Winter Meeting 2016, 7-9 Dec 2016, London. (Unpublished)

Patel, Mitesh, Pilcher, Janine, Hancox, Robert J., Sheahan, Davitt, Pritchard, Alison, Braithwaite, Irene, Shaw, Dominick E., Black, Peter, Weatherall, Mark and Beasley, Richard (2015) The use of β2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis. npj Primary Care Respiratory Medicine, 25 . 14099/1-14099/9. ISSN 2055-1010

Patel, Mitesh, Pilcher, Janine, Munro, Claire, Hosking, Alexander, Pritchard, Alison, Shaw, Dominick, Black, Peter, Weatherall, Mark and Beasley, Richard (2013) Short-acting β-agonist use as a marker of current asthma control. Journal of Allergy and Clinical Immunology: In Practice, 1 (4). pp. 370-377. ISSN 2213-2201

Patel, Mitesh, Pilcher, Janine, Pritchard, Alison, Perrin, Kyle, Travers, Justin, Shaw, Dominick, Holt, Shaun, Harwood, Matire, Black, Peter, Weatherall, Mark and Beasley, Richard (2013) Efficacy and safety of maintenance and reliever combination budesonide–formoterol inhaler in patients with asthma at risk of severe exacerbations: a randomised controlled trial. Lancet Respiratory Medicine, 1 (1). pp. 32-42. ISSN 2213-2619

Patel, Mitesh, Pilcher, Janine, Reddel, Helen K., Pritchard, Alison, Corin, Andrew, Helm, Colin, Tofield, Christopher, Shaw, Dominick, Black, Peter, Weatherall, Mark and Beasley, Richard (2013) Metrics of salbutamol use as predictors of future adverse outcomes in asthma. Clinical & Experimental Allergy, 43 (10). pp. 1144-1151. ISSN 1365-2222

Patel, Mitesh, Pilcher, Janine, Reddel, Helen K., Qi, Victoria, Mackey, Bill, Tranquilino, Tyronne, Shaw, Dominick E. and Black, Peter (2014) Predictors of severe exacerbations, poor asthma control, and β-agonist overuse for patients with asthma. Journal of Allergy and Clinical Immunology: In Practice, 2 (6). 751-758.e1. ISSN 2213-2201

Patel, Mitesh, Pilcher, Janine, Travers, Justin, Perrin, Kyle, Shaw, Dominick, Black, Peter, Weatherall, Mark and Beasley, Richard (2013) Use of metered-dose inhaler electronic monitoring in a real-world asthma randomized controlled trial. Journal of Allergy and Clinical Immunology: In Practice, 1 (1). pp. 83-91. ISSN 2213-2201

Patel, Mitesh Dilipkumar Kantilal and Shaw, Dominick E. (2015) A review of standard pharmacological therapy for adult asthma - Steps 1 to 5. Chronic Respiratory Disease, 12 (2). pp. 165-176. ISSN 1479-9723

Pavlovskaya, Galina E. and Meersmann, Thomas (2014) Spatial mapping of flow-induced molecular alignment in a noncrystalline biopolymer fluid using double quantum filtered (DQF) 23Na MRI. Journal of Physical Chemistry Letters, 5 (15). pp. 2632-2636. ISSN 1948-7185

Pavlovskaya, Galina E., Meersmann, Thomas, Jin, Chunyu and Rigby, Sean P. (2018) Fluid flow in a porous medium with transverse permeability discontinuity. Physical Review Fluids, 3 (4). 044102-1. ISSN 2469-990X

Pavlovskaya, Galina E., Six, Joseph S., Meersman, Thomas, Gopinathan, Navin and Rigby, Sean P. (2015) NMR Imaging of low pressure, gas-phase transport in packed beds using hyperpolarized xenon-129. AIChE Journal, 61 (11). pp. 4013-4016. ISSN 1547-5905

Philp, Christopher J., Siebeke, Ivonne, Clements, Debbie, Miller, Suzanne, Hapgood, Anthony, John, Alison E., Navaratnam, Vidya, Hubbard, Richard B., Jenkins, Gisli and Johnson, Simon R. (2017) ECM crosslinking enhances fibroblast growth and protects against matrix proteolysis in lung fibrosis. American Journal of Respiratory Cell and Molecular Biology, 58 (5). ISSN 1535-4989

Pilcher, Janine, Patel, Mitesh, Pritchard, Alison, Thayabaran, Darmiga, Ebmeier, Stefan, Shaw, Dominick E., Black, Peter, Braithwaite, Irene, Weatherall, Mark and Beasley, Richard (2017) Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial. npj Primary Care Respiratory Medicine, 27 (1). p. 33. ISSN 2055-1010

Pilcher, Janine, Patel, Mitesh, Reddel, Helen K., Pritchard, Alison, Black, Peter, Shaw, Dominick E., Holt, Shaun, Weatherall, Mark and Beasley, Richard (2016) Effect of smoking status on the efficacy of the SMART regimen in high risk asthma. Respirology, 21 (5). pp. 858-866. ISSN 1440-1843

Poghosyan, Anna, Patel, Jamie K., Clifford, Rachel L. and Knox, Alan J. (2016) Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells. Biochemical and Biophysical Research Communications, 476 (4). pp. 431-437. ISSN 1090-2104

Portelli, Michael, Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H. and Sayers, Ian (2014) Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB Journal, 28 (2). pp. 923-934. ISSN 0892-6638

Portelli, Michael A., Hodge, Emily and Sayers, Ian (2015) Genetic risk factors for the development of allergic disease identified by genome-wide association. Clinical & Experimental Allergy, 45 (1). pp. 21-31. ISSN 1365-2222

Portelli, Michael A., Moseley, C., Stewart, Ceri E., Postma, Dirkje S., Howarth, P., Warner, J.A., Holloway, J.W., Koppelman, Gerard H. and Sayers, Ian (2016) Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients. Allergy . ISSN 1398-9995

Portelli, Michael A. and Sayers, Ian (2016) Genome-wide association studies in asthma. eLS . pp. 1-10.

Portelli, Michael A., Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H. and Sayers, Ian (2014) Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB Journal, 28 (2). pp. 923-934. ISSN 0892-6638

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Rabinovich, Roberto A., Miller, Bruce E., Wrobel, Karolina, Ranjit, Kareshma, Williams, Michelle C., Drost,, Ellen, Edwards, Lisa D., Lomas, David A., Rennard, Stephen I., Agustí, Alvar, Tal-Singer, Ruth, Vestbo, Jørgen, Wouters, Emiel F.M., John, Michelle, van Beek, Edwin J.R., Murchison, John T., Bolton, Charlotte E., MacNee, William and Huang, Jeffrey T.J. (2016) Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD. European Respiratory Journal, 47 (5). pp. 1365-1373. ISSN 0903-1936

Rajasekar, P., Clifford, R.L., MacIsaac, J.L., McEwen, L.M., Kobor, M. and Knox, A.J. (2017) Use of novel DNA methylation signatures to distinguish between human airway structural cell types. In: American Thoracic Society 2017 International Conference, 19-24 May 2017, Washington, D.C., USA.

Ravipati, Srinivasarao, Baldwin, David R., Barr, Helen L., Fogarty, Andrew W. and Barrett, David A. (2015) Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients. Metabolomics, 11 (6). pp. 1600-1611. ISSN 1573-3890

Rimington, Tracy L., Hodge, Emily, Billington, Charlotte K., Bhaker, Sangita, K C, Binaya, Kilty, Iain, Jelinsky, Scott, Hall, Ian P. and Sayers, Ian (2017) Defining the inflammatory signature of human lung explant tissue in the presence and absence of glucocorticoid. F1000Research, 6 . 460/1-460/11. ISSN 2046-1402

Rogers, Natasha K., Clements, Debbie, Dongre, Arundhati, Harrison, Timothy W., Shaw, Dominick E. and Johnson, Simon R. (2014) Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma. PLoS ONE, 9 (2). e90565/1-e90565/12. ISSN 1932-6203

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Sadykhov, E.G., Pirogov, Yu. A., Anisimov, N.V., Gulyaev, M .V., Pavlovskaya, G. E., Meersmann, Thomas, Belyaev, V.N. and Fomina, D.V. (2018) Magnetic resonance imaging on sodium nuclei: potential medical applications of 23Na MRI. Applied Magnetic Resonance . pp. 1-33. ISSN 1613-7507

Safavi, Shahideh, Prayle, Andrew P., Hall, Ian P. and Parmar, Jasvir (2017) Azithromycin for treatment of bronchiolitis obliterans syndrome in adult lung transplant recipients. Cochrane Database of Systematic Reviews, 2017 (9). CD012782. ISSN 1469-493X

Saini, Gauri, Porte, Joanne, Weinreb, Paul H, Violette, Sheila M, Wallace, William A, McKeever, Tricia M. and Jenkins, Gisli (2015) αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease. European Respiratory Journal, 46 (2). pp. 486-494. ISSN 1399-3003

Sayers, Ian, Portelli, Michael A. and Siedlinski, Mateusz (2015) Response. FASEB Journal, 29 (12). p. 4759. ISSN 0892-6638

Selvarajah, Senthooran, Todd, Ian, Tighe, Patrick J., John, Michelle, Bolton, Charlotte E., Harrison, Timothy W. and Fairclough, Lucy C. (2016) Multiple circulating cytokines are coelevated in chronic obstructive pulmonary disease. Mediators of Inflammation, 2016 . p. 3604842. ISSN 1466-1861

Shaw, Dominick E., Sousa, Ana R., Fowler, Stephen J., Fleming, Louise J., Roberts, Graham, Corfield, Julie, Pandis, Ioannis, Bansal, Aruna T., Bel, Elisabeth H., Auffray, Charles, Compton, Chris H., Bisgaard, Hans, Bucchioni, Enrica, Caruso, Massimo, Chanez, Pascal, Dahlen, Barbro, Dahlen, Sven-Erik, Dyson, Kerry, Frey, Urs, Geiser, Thomas, Gerhardsson de Verdier, Maria, Gibeon, David, Guo, Yi-ke, Hashimoto, Simone, Hedlin, Gunilla, Jeyasingham, Elizabeth, Hekking, Pieter-Paul W., Higenbottam, Tim, Horváth, Ildikó, Knox, Alan J., Krug, Norbert, Erpenbeck, Veit J., Larsson, Lars X., Lazarinis, Nikos, Matthews, John G., Middelveld, Roelinde, Montuschi, Paolo, Musial, Jacek, Myles, David, Pahus, Laurie, Sandström, Thomas, Seibold, Wolfgang, Singer, Florian, Strandberg, Karin, Vestbo, Jorgen, Vissing, Nadja, von Garnier, Christophe, Adcock, Ian M., Wagers, Scott, Rowe, Anthony, Howarth, Peter, Wagener, Ariane H., Djukanovic, Ratko, Sterk, Peter J. and Chung, Kian Fan (2015) Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. European Respiratory Journal, 46 (5). pp. 1308-1321. ISSN 1399-3003

Singh, Shailendra R., Billington, Charlotte K., Sayers, Ian and Hall, Ian P. (2014) Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity. Respiratory Research, 15 (1). 57/1-57/11. ISSN 1465-993X

Six, Joseph S., Hughes-Riley, Theodore, Lilburn, David M.L., Dorkes, Alan C., Stupic, Karl F., Shaw, Dominick E., Morris, Peter G., Hall, Ian P., Pavlovskaya, Galina E. and Meersmann, Thomas (2014) Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr. Magnetic Resonance Imaging, 32 (1). pp. 48-53. ISSN 1873-5894

Skeggs, Andrew, McKeever, Tricia M., Duley, Lelia, Mitchell, Eleanor, Bradshaw, Lucy, Mortimer, Kevin, Walker, Samantha, Parrott, Steve, Wilson, Andrew, Pavord, Ian, Brightling, Chris, Thomas, Mike, Price, David, Devereux, Graham, Higgins, Bernard, Harrison, Timothy W. and Haydock, Rebecca (2016) FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations. Trials, 17 . p. 499. ISSN 1745-6215

Slater, Mariel, Rivett, Damian W., Williams, Lisa, Martin, Matthew, Harrison, Timothy W., Sayers, Ian, Bruce, Kenneth D. and Shaw, Dominick E. (2014) The impact of azithromycin therapy on the airway microbiota in asthma. Thorax, 69 (7). pp. 673-674. ISSN 1468-3296

Slater, Mariel, Torr, Elizabeth, Harrison, Timothy W., Forrester, Doug L., Knox, Alan, Shaw, Dominick E. and Sayers, Ian (2016) The differential effects of azithromycin on the airway epithelium in vitro and in vivo. Physiological Reports, 4 (18). e12960/1-e12960/15. ISSN 2051-817X

Slater, Mariel G., Pavord, Ian D. and Shaw, Dominick E. (2016) Step 4: stick or twist? A review of asthma therapy. BMJ Open Respiratory Research, 3 (1). e000143/1-e000143/7. ISSN 2052-4439

Steiner, Michael C., Lowe, Derek, Beckford,, Katy, Blakey, John, Bolton, Charlotte E., Elkin, Sarah, Man, William D -C., Roberts, C. Michael, Sewell, Louise, Walker, Paul and Singh, Sally J. (2017) Socioeconomic deprivation and the outcome of pulmonary rehabilitation in England and Wales. Thorax, 72 (6). pp. 530-537. ISSN 1468-3296

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Takahashi, Kentaro, Pavlidis, Stelios, Ng Kee Kwong, Francois, Hoda, Uruj, Rossios, Christos, Sun, Kai, Loza, Matthew, Baribaud, Fred, Chanez, Pascal, Fowler, Steve J., Horvath, Ildiko, Montuschi, Paolo, Singer, Florian, Musial, Jacek, Dahlen, Barbro, Dahlen, Sven-Eric, Krug, Norbert, Sandstrom, Thomas, Shaw, Dominic E., Lutter, Rene, Bakke, Per, Fleming, Louise J., Howarth, Peter H., Caruso, Massimo, Sousa, Ana R., Corfield, Julie, Auffray, Charles, De Meulder, Bertrand, Lefaudeux, Diane, Djukanovic, Ratko, Sterk, Peter J., Guo, Yike, Adcock, Ian M. and Chung, Kian Fan (2018) Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis. European Respiratory Journal, 51 (5). p. 1702173. ISSN 0903-1936

Thorgeirsson, T.E., Steinberg, S., Reginsson, G.W., Bjornsdottir, G., Rafnar, T., Jonsdottir, I., Helgadottir, A., Gretarsdottir, S., Helgadottir, H., Jonsson, S., Matthiasson, S.E., Gislason, T., Tyrfingsson, T., Gudbjartsson, T., Isaksson, H.J., Hardardottir, H., Sigvaldason, A., Kiemeney, L.A., Haugen, A., Zienolddiny, S., Wolf, H.J., Franklin, W.A., Panadero, A., Mayordomo, J.I., Hall, I.P., Rönmark, E., Lundbäck, B., Dirksen, A., Ashraf, H., Pedersen, J.H., Masson, G., Sulem, P., Thorsteinsdottir, U., Gudbjartsson, D.F. and Stefansson, K. (2016) A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences. Molecular Psychiatry, 21 (5). pp. 594-600. ISSN 1359-4184

Torr, Elizabeth, Heath, Meg, Mee, Maureen, Shaw, Dominick E., Sharp, Tyson V. and Sayers, Ian (2016) Expression of polycomb protein BMI-1 1 maintains the plasticity of basal 2 bronchial epithelial cells. Physiological Reports, 4 (16). e12847. ISSN 2051-817X

Tulah, Asif S., Holloway, John W. and Sayers, Ian (2013) Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children. BMC Medical Genetics, 14 (100). ISSN 1471-2350

Turan, N., Edwards, M.J., Bates, S., Shaw, D., Chung, K.F., Loza, M.J., James, A. and Van Oosterhout, A. (2018) IL-6 pathway upregulation in subgroup of severe asthma is associated with neutrophilia and poor lung function. Clinical & Experimental Allergy, 48 (4). pp. 475-478. ISSN 0954-7894

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Wain, Louise V., Sayers, Ian, Artigas, María Soler, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma’en, Sin, Don D., Bossé, Yohan, Nickle, David C., Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelingsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia M., Shrine, Nick, Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P. and Tobin, Martin D. (2014) Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction. PLoS Genetics, 10 (5). e1004314/1-e1004314/14. ISSN 1553-7404

Wain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., Johnson, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Sayers, Ian and Hall, Ian P. (2017) Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49 . pp. 416-425. ISSN 1546-1718

Wain, Louise V., Shrine, Nick, Miller, Suzanne, Jackson, Victoria E., Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K., Kheirallah, Abdul Kader, Allen, Richard, Cook, James P., Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S., Paré, Peter D., Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L., Thomson, Neil C., Zeggini, Eleftheria, Morris, Andrew P., Marchini, Jonathan, Strachan, David P., Tobin, Martin D. and Hall, Ian P. (2015) Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lancet Respiratory Medicine, 3 (10). pp. 769-781. ISSN 2213-2619

Williams, Neil C., Hunter, Kirsty A., Shaw, Dominick E., Jackson, Kim G., Sharpe, Graham R. and Johnson, Michael A. (2017) Comparable reductions in hyperpnoea-induced bronchoconstriction and markers of airway inflammation after supplementation with 6·2 and 3·1 g/d of long-chain n-3 PUFA in adults with asthma. British Journal of Nutrition, 117 (10). pp. 1379-1389. ISSN 1475-2662

Williams, Neil C., Johnson, Michael A., Shaw, Dominick E., Spendlove, Ian, Vulevic, Jelena, Sharpe, Graham R. and Hunter, Kirsty A. (2016) A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation. British Journal of Nutrition, 116 (05). pp. 798-804. ISSN 1475-2662

Wilson, Emma, McKeever, Tricia M., Hargadon, Beverley, Hearson, Glenn, Anderson, John, Hodgson, David, Bailey, Helen, Meakin, Garry, Thomas, Mike, Pavord, Ian D., Harrison, Timothy W. and Shaw, Dominick E. (2014) Exhaled nitric oxide and inhaled corticosteroid dose reduction in asthma: a cohort study. European Respiratory Journal, 44 (6). pp. 1705-1707. ISSN 1399-3003

Wilson, Emma Elizabeth, McKeever, Tricia M., Lobb, Claire, Sherriff, Tom, Gupta, Luke, Hearson, Glenn, Martin, Neil, Lindley, Martin R. and Shaw, Dominick E. (2014) Respiratory muscle specific warm-up and elite swimming performance. British Journal of Sports Medicine, 48 (9). pp. 789-791. ISSN 1473-0480

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Zaccardi, Francesco, Davies, Melanie J., Dhalwani, Nafeesa N., Webb, David R., Housley, Gemma, Shaw, Dominick E., Hatton, James W. and Khunti, Kamlesh (2016) Trends in hospital admissions for hypoglycaemia in England: a retrospective, observational study. Lancet Diabetes & Endocrinology, 4 (8). pp. 677-685. ISSN 2213-8595

Zaccardi, Francesco, Webb, David R., Davies, Melanie J., Dhalwani, Nafeesa N., Gray, Laura J., Chatterjee, Sudesna, Housley, Gemma, Shaw, Dominick, Hatton, James W. and Khunti, Kamlesh (2017) Predicting hospital stay, mortality and readmission in people admitted for hypoglycaemia: prognostic models derivation and validation. Diabetologia, 60 (6). pp. 1007-1015. ISSN 0012-186X

Zaccardi, Francesco, Webb, David R., Davies, Melanie J., Dhalwani, Nafeesa N., Housley, Gemma, Shaw, Dominic, Hatton, James W. and Khunti, Kamlesh (2017) Risk factors and outcome differences in hypoglycaemia-related hospital admissions: a case-control study in England. Diabetes, Obesity and Metabolism, 19 (10). pp. 1371-1378. ISSN 1462-8902

Zamberlan, Francesco, Lesbats, Clémentine, Rogers, Nicola J., Krupa, James L., Pavlovskaya, Galina E., Thomas, Neil R., Faas, Henryk and Meersmann, Thomas (2015) Molecular sensing with hyperpolarized 129Xe using switchable chemical exchange relaxation transfer. ChemPhysChem, 16 (11). pp. 2294-2298. ISSN 1439-7641