Gradient delivery of bioactive molecules across porous hydrogels
Eltaher, Hoda M.M.A. (2016) Gradient delivery of bioactive molecules across porous hydrogels. PhD thesis, University of Nottingham.
Tissue regeneration approaches involve the recreation of biochemical and mechanical cues dictating tissue fate. Gradients of chemical cues are common in the natural microenvironment and are usually accompanied with gradual changes in cellular responses. Consequently, thorough understanding of biomolecule gradient development, their effective concentrations and the corresponding cellular responses as a function of time and space are essential for efficient design of scaffolds for biomedical applications.
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