Chain walking of allylrhodium species towards esters during rhodium-catalyzed nucleophilic allylations of imines

Martínez, Jose I. and Smith, Joshua S. and Hepburn, Hamish B. and Lam, Hon Wai (2015) Chain walking of allylrhodium species towards esters during rhodium-catalyzed nucleophilic allylations of imines. Angewandte Chemie International Edition . ISSN 1433-7851

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Abstract

Allylrhodium species derived from δ-trifluoroboryl β,γ-unsaturated esters undergo chain walking towards the ester moiety.The resulting allylrhodium species react with imines to give products containing two new stereocenters and a Z-alkene. By using a chiral diene ligand, products can be obtained with high enantioselectivities, where a pronounced matched/mismatched effect with the chirality of the allyltrifluoroborate is evident.

Item Type: Article
Schools/Departments: University of Nottingham UK Campus > Faculty of Science > School of Chemistry
Identification Number: https://doi.org/10.1002/anie.201508964
Depositing User: Bramwell, Roseanna
Date Deposited: 09 Nov 2015 09:31
Last Modified: 15 Sep 2016 06:02
URI: http://eprints.nottingham.ac.uk/id/eprint/30669

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