The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia

Driver, Ian, Blockley, Nicholas, Fisher, Joseph, Francis, Susan and Gowland, Penny A. (2010) The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia. NeuroImage, 51 (1). pp. 274-279. ISSN 1053-8119

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Abstract

Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect. In this work BOLD/R2* CVR was investigated by using a device which provided small, repeatable and stable steps in PETCO2, whilst maintaining a steady PETO2 level. Significant CVR was observed in both grey and white matter at both 3 & 7T, whilst an approximately linear relationship found between R2* CVR and field strength has implications for BOLD models and calibration. Grey matter R2* CVR was 0.066±0.004 s-1 mmHg-1 at 3T and 0.141±0.008 s-1mmHg-1 at 7T. White matter R2* CVR was 0.021±0.003 s-1mmHg-1 at 3T and 0.040±0.007 s-1mmHg-1 at 7T.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/706319
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Physics and Astronomy
Identification Number: https://doi.org/10.1016/j.neuroimage.2009.12.113
Related URLs:
URLURL Type
http://dx.doi.org/10.1016/j.neuroimage.2009.12.113Publisher
Depositing User: Driver, Mr Ian
Date Deposited: 17 Jun 2010 16:41
Last Modified: 04 May 2020 16:29
URI: https://eprints.nottingham.ac.uk/id/eprint/1313

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