Browse by Authors and EditorsJump to: Article Number of items: 34. ArticleAllen, Richard J., Porte, Joanne, Braybrooke, Rebecca, Flores, Carlos, Fingerlin, Tasha E., Oldham, Justin M., Guillen-Guio, Beatriz, Ma, Shwu-Fan, Okamoto, Tsukasa, John, Alison E., Obeidat, Ma'en, Yang, Ivana V., Henry, Amanda, Hubbard, Richard B., Navaratnam, Vidya, Saini, Gauri, Thompson, Norma, Booth, Helen L., Hart, Simon P., Hill, Mike R., Hirani, Nik, Maher, Toby M., McAnulty, Robin J., Millar, Ann B., Molyneaux, Philip L., Parfrey, Helen, Rassl, Doris M., Whyte, Moira K.B., Fahy, William A., Marshall, Richard P., Oballa, Eunice, Bossé, Yohan, Nickle, David C., Sin, Don D., Timens, Wim, Shrine, Nick, Sayers, Ian, Hall, Ian P., Noth, Imre, Schwartz, David A., Tobin, Martin D., Wain, Louise V. and Jenkins, R. Gisli (2017) Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. Lancet Respiratory Medicine, 5 (11). pp. 869-880. ISSN 2213-2619 Rimington, Tracy L., Hodge, Emily, Billington, Charlotte K., Bhaker, Sangita, K C, Binaya, Kilty, Iain, Jelinsky, Scott, Hall, Ian P. and Sayers, Ian (2017) Defining the inflammatory signature of human lung explant tissue in the presence and absence of glucocorticoid. F1000Research, 6 . 460/1-460/11. ISSN 2046-1402 Kheirallah, Alexander K., de Moor, Cornelia H., Faiz, Alen, Sayers, Ian and Hall, Ian P. (2017) Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways. BMC Genomics, 18 (1). p. 248. ISSN 1471-2164 Wain, Louise V., Shrine, Nick, Artigas, María Soler, Erzurumluoglu, A. Mesut, Noyvert, Boris, Bossini-Castillo, Lara, Obeidat, Ma’en, Henry, Amanda P., Portelli, Michael A., Hall, Robert J., Billington, Charlotte K., Rimington, Tracy L., Fenech, Anthony G., Johnson, Catherine, Blake, Tineka, Jackson, Victoria E., Allen, Richard J., Prins, Bram P., Campbell, Archie, Sayers, Ian and Hall, Ian P. (2017) Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature Genetics, 49 . pp. 416-425. ISSN 1546-1718 Artigas, María Soler, Wain, Louise V., Shrine, Nick, McKeever, Tricia M., Sayers, Ian, Hall, Ian P. and Tobin, Martin D. (2017) Targeted sequencing of lung function loci in chronic obstructive pulmonary disease cases and controls. PLoS ONE, 12 (1). e0170222/1-e0170222/17. ISSN 1932-6203 Portelli, Michael A. and Sayers, Ian (2016) Genome-wide association studies in asthma. eLS . pp. 1-10. Miller, Suzanne, Henry, Amanda P., Hodge, Emily, Kheirallah, Alexander K., Billington, Charlotte K., Rimington, Tracy L., Bhaker, Sangita K., Obeidat, Ma’en, Melén, Erik, Merid, Simon K., Swan, Caroline, Gowland, Catherine, Nelson, Carl P., Stewart, Ceri E., Bolton, Charlotte E., Kilty, Iain, Malarstig, Anders, Parker, Stuart G., Moffatt, Miriam F., Wardlaw, Andrew J., Hall, Ian P. and Sayers, Ian (2016) The Ser82 RAGE variant affects lung function and serum RAGE in smokers and sRAGE production in vitro. PLoS ONE, 11 (10). e0164041/1-e0164041/16. ISSN 1932-6203 Portelli, Michael A., Moseley, C., Stewart, Ceri E., Postma, Dirkje S., Howarth, P., Warner, J.A., Holloway, J.W., Koppelman, Gerard H. and Sayers, Ian (2016) Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients. Allergy . ISSN 1398-9995 Slater, Mariel, Torr, Elizabeth, Harrison, Timothy W., Forrester, Doug L., Knox, Alan, Shaw, Dominick E. and Sayers, Ian (2016) The differential effects of azithromycin on the airway epithelium in vitro and in vivo. Physiological Reports, 4 (18). e12960/1-e12960/15. ISSN 2051-817X Torr, Elizabeth, Heath, Meg, Mee, Maureen, Shaw, Dominick E., Sharp, Tyson V. and Sayers, Ian (2016) Expression of polycomb protein BMI-1 1 maintains the plasticity of basal 2 bronchial epithelial cells. Physiological Reports, 4 (16). e12847. ISSN 2051-817X John, Michelle, McKeever, Tricia M., Haddad, Maath Al, Hall, Ian P., Sayers, Ian, Cockcroft, John R. and Bolton, Charlotte E. (2016) Traditional and emerging indicators of cardiovascular risk in chronic obstructive pulmonary disease. Chronic Respiratory Disease, 13 (3). pp. 247-255. ISSN 1479-9731 Miller, Suzanne, Melén, Erik, Merid, S. K., Hall, Ian P. and Sayers, Ian (2016) Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development. Respiratory Research, 17 (95). ISSN 1465-993X Ketelaar, M.E., Nawijn, Martijn C., Shaw, Dominick E., Koppelman, Gerard H. and Sayers, Ian (2016) The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma. Clinical & Experimental Allergy, 46 (6). pp. 884-887. ISSN 1365-2222 Kheirallah, Alexander K., Miller, Suzanne, Hall, Ian P. and Sayers, Ian (2016) Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology. Advances in Genetics, 93 . pp. 57-145. ISSN 0065-2660 Jackson, Victoria E., Ntalla, Ioanna, Sayers, Ian, Morris, Richard, Whincup, Peter, Casas, Juan-Pablo, Amuzu, Antoinette, Choi, Minkyoung, Dale, Caroline, Kumari, Meena, Engmann, Jorgen, Kalsheker, Noor, Chappell, Sally, Guetta-Baranes, Tamar, McKeever, Tricia M., Palmer, Colin N.A., Tavendale, Roger, Holloway, John W., Sayer, Avan A., Dennison, Elaine M., Cooper, Cyrus, Bafadhel, Mona, Barker, Bethan, Brightling, Chris, Bolton, Charlotte E., John, Michelle E., Parker, Stuart G., Moffat, Miriam F., Wardlaw, Andrew J., Connolly, Martin J., Porteous, David J., Smith, Blair H., Padmanabhan, Sandosh, Hocking, Lynne, Stirrups, Kathleen E., Deloukas, Panos, Strachan, David P., Hall, Ian P., Tobin, Martin D. and Wain, Louise V. (2016) Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. Thorax, 71 (6). pp. 501-509. ISSN 1468-3296 Ierodiakonou, Despo, Portelli, Michael A., Postma, Dirkje S., Koppelman, Gerard H., Gerritsen, Jorrit, ten Hacken, Nick H.T., Timens, Wim, Boezen, H. Marike, Vonk, Judith M. and Sayers, Ian (2016) Urokinase plasminogen activator receptor polymorphisms and airway remodelling in asthma. European Respiratory Journal, 47 (5). pp. 1568-1571. ISSN 1399-3003 Sayers, Ian, Portelli, Michael A. and Siedlinski, Mateusz (2015) Response. FASEB Journal, 29 (12). p. 4759. ISSN 0892-6638 Artigas, María Soler, Wain, Louise V., Miller, Suzanne, Kheirallah, Abdul Kader, Huffman, Jennifer E., Ntalla, Ioanna, Shrine, Nick, Obeidat, Ma’en, Trochet, Holly, McArdle, Wendy L., Alves, Alexessander Couto, Hui, Jennie, Zhao, Jing Hua, Joshi, Peter K., Teumer, Alexander, Albrecht, Eva, Imboden, Medea, Rawal, Rajesh, Lopez, Lorna M., Marten, Jonathan, Enroth, Stefan, Surakka, Ida, Polasek, Ozren, Lyytikäinen, Leo-Pekka, Granell, Raquel, Hysi, Pirro G., Flexeder, Claudia, Mahajan, Anubha, Beilby, John, Bossé, Yohan, Brandsma, Corry-Anke, Campbell, Harry, Gieger, Christian, Gläser, Sven, González, Juan R., Grallert, Harald, Hammond, Chris J., Harris, Sarah E., Hartikainen, Anna-Liisa, Heliövaara, Markku, Henderson, John, Hocking, Lynne, Horikoshi, Momoko, Hutri-Kähönen, Nina, Ingelsson, Erik, Johansson, Åsa, Kemp, John P., Kolcic, Ivana, Kumar, Ashish, Lind, Lars, Melén, Erik, Musk, Arthur W., Navarro, Pau, Nickle, David C., Padmanabhan, Sandosh, Raitakari, Olli T., Ried, Janina S., Ripatti, Samuli, Schulz, Holger, Scott, Robert A., Sin, Don D., Starr, John M., Deloukas, Panos, Hansell, Anna L., Hubbard, Richard, Jackson, Victoria E., Marchini, Jonathan, Pavord, Ian, Thomson, Neil C., Zeggini, Eleftheria, Viñuela, Ana, Völzke, Henry, Wild, Sarah H., Wright, Alan F., Zemunik, Tatijana, Jarvis, Deborah L., Spector, Tim D., Evans, David M., Lehtimäki, Terho, Vitart, Veronique, Kähönen, Mika, Gyllensten, Ulf, Rudan, Igor, Deary, Ian J., Karrasch, Stefan, Probst-Hensch, Nicole M., Heinrich, Joachim, Stubbe, Beate, Wilson, James F., Wareham, Nicholas J., James, Alan L., Morris, Andrew P., Jarvelin, Marjo-Riitta, Hayward, Caroline, Sayers, Ian, Strachan, David P., Hall, Ian P. and Tobin, Martin D. (2015) Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature Communications, 6 . 8658/1-8658/12. ISSN 2041-1723 Wain, Louise V., Shrine, Nick, Miller, Suzanne, Jackson, Victoria E., Ntalla, Ioanna, Artigas, María Soler, Billington, Charlotte K., Kheirallah, Abdul Kader, Allen, Richard, Cook, James P., Probert, Kelly, Obeidat, Ma'en, Bossé, Yohan, Hao, Ke, Postma, Dirkje S., Paré, Peter D., Ramasamy, Adaikalavan, Mägi, Reedik, Mihailov, Evelin, Reinmaa, Eva, Melén, Erik, O'Connell, Jared, Frangou, Eleni, Delaneau, Olivier, Freeman, Colin, Petkova, Desislava, McCarthy, Mark, Sayers, Ian, Deloukas, Panos, Hubbard, Richard, Pavord, Ian, Hansell, Anna L., Thomson, Neil C., Zeggini, Eleftheria, Morris, Andrew P., Marchini, Jonathan, Strachan, David P., Tobin, Martin D. and Hall, Ian P. (2015) Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lancet Respiratory Medicine, 3 (10). pp. 769-781. ISSN 2213-2619 Portelli, Michael A., Hodge, Emily and Sayers, Ian (2015) Genetic risk factors for the development of allergic disease identified by genome-wide association. Clinical & Experimental Allergy, 45 (1). pp. 21-31. ISSN 1365-2222 Koning, Henk, Oosterhout, Antoon J.M. van, Brouwer, Uilke, Boef, Lisette E. den, Gras, Renée, Reinders-Luinge, Marjan, Brandsma, Corry-Anke, Toorn, Marco van der, Hylkema, Machteld N., Willemse, Brigitte W.M., Sayers, Ian, Koppelman, Gerard H. and Nawijn, Martijn C. (2014) Mouse Protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo. PLoS ONE, 9 (7). e98197/1-e98197/10. ISSN 1932-6203 Loth, Daan W., Artigas, María Soler, Gharib, Sina A., Wain, Louise V., Franceschini, Nora, Koch, Beate, Pottinger, Tess D., Smith, Albert Vernon, Duan, Qing, Oldmeadow, Chris, Lee, Mi Kyeong, Strachan, David P., James, Alan L., Huffman, Jennifer E., Vitart, Veronique, Ramasamy, Adaikalavan, Wareham, Nicholas J., Kaprio, Jaakko, Wang, Xin-Qun, Trochet, Holly, Kähönen, Mika, Flexeder, Claudia, Albrecht, Eva, Lopez, Lorna M., de Jong, Kim, Thyagarajan, Bharat, Alves, Alexessander Couto, Enroth, Stefan, Omenaas, Ernst, Joshi, Peter K., Fall, Tove, Viñuela, Ana, Launer, Lenore J., Loehr, Laura R., Fornage, Myriam, Li, Guo, Wilk, Jemma B., Tang, Wenbo, Manichaikul, Ani, Lahousse, Lies, Harris, Tamara B., North, Kari E., Rudnicka, Alicja R., Hui, Jennie, Gu, Xiangjun, Lumley, Thomas, Wright, Alan F., Hastie, Nicholas D., Campbell, Susan, Kumar, Rajesh, Pin, Isabelle, Scott, Robert A., Pietiläinen, Kirsi H., Surakka, Ida, Liu, Yongmei, Holliday, Elizabeth G., Schulz, Holger, Heinrich, Joachim, Davies, Gail, Vonk, Judith M., Wojczynski, Mary, Pouta, Anneli, Johansson, Åsa, Wild, Sarah H., Ingelsson, Erik, Rivadeneira, Fernando, Völzke, Henry, Hysi, Pirro G., Eiriksdottir, Gudny, Morrison, Alanna C., Rotter, Jerome I., Gao, Wei, Postma, Dirkje S., White, Wendy B., Rich, Stephen S., Hofman, Albert, Aspelund, Thor, Couper, David, Smith, Lewis J., Psaty, Bruce M., Lohman, Kurt, Burchard, Esteban G., Uitterlinden, André G., Garcia, Melissa, Joubert, Bonnie R., McArdle, Wendy L., Musk, A Bill, Hansel, Nadia, Heckbert, Susan R., Zgaga, Lina, van Meurs, Joyce B.J., Navarro, Pau, Rudan, Igor, Oh, Yeon-Mok, Redline, Susan, Jarvis, Deborah L., Zhao, Jing Hua, Rantanen, Taina, O'Connor, George T., Ripatti, Samuli, Scott, Rodney J., Karrasch, Stefan, Grallert, Harald, Gaddis, Nathan C., Starr, John M., Wijmenga, Cisca, Minster, Ryan L., Lederer, David J., Pekkanen, Juha, Gyllensten, Ulf, Campbell, Harry, Morris, Andrew P., Gläser, Sven, Hammond, Christopher J., Burkart, Kristin M, Beilby, John, Kritchevsky, Stephen B., Gudnason, Vilmundur, Hancock, Dana B., Williams, O Dale, Polasek, Ozren, Zemunik, Tatijana, Kolcic, Ivana, Petrini, Marcy F., Wjst, Matthias, Kim, Woo Jin, Porteous, David J., Smith, Blair H., Viljanen, Anne, Heliövaara, Markku, Attia, John R., Sayers, Ian, Hampel, Regina, Gieger, Christian, Deary, Ian J, Boezen, H. Marike, Newman, Anne, Jarvelin, Marjo-Riitta, Wilson, James F, Lind, Lars, Stricker, Bruno H., Teumer, Alexander, Spector, Timothy D., Melén, Erik, Peters, Marjolein J., Lange, Leslie A., Barr, R. Graham, Bracke, Ken R., Verhamme, Fien M., Sung, Joohon, Hiemstra, Pieter S., Cassano, Patricia A., Sood, Akshay, Hayward, Caroline, Dupuis, Josée, Hall, Ian P., Brusselle, Guy G., Tobin, Martin D. and London, Stephanie J. (2014) Genome-wide association analysis identifies six new loci associated with forced vital capacity. Nature Genetics, 46 (7). pp. 669-677. ISSN 1546-1718 Slater, Mariel, Rivett, Damian W., Williams, Lisa, Martin, Matthew, Harrison, Timothy W., Sayers, Ian, Bruce, Kenneth D. and Shaw, Dominick E. (2014) The impact of azithromycin therapy on the airway microbiota in asthma. Thorax, 69 (7). pp. 673-674. ISSN 1468-3296 Singh, Shailendra R., Billington, Charlotte K., Sayers, Ian and Hall, Ian P. (2014) Clonally expanded human airway smooth muscle cells exhibit morphological and functional heterogeneity. Respiratory Research, 15 (1). 57/1-57/11. ISSN 1465-993X Wain, Louise V., Sayers, Ian, Artigas, María Soler, Portelli, Michael A., Zeggini, Eleftheria, Obeidat, Ma’en, Sin, Don D., Bossé, Yohan, Nickle, David C., Brandsma, Corry-Anke, Malarstig, Anders, Vangjeli, Ciara, Jelingsky, Scott A., John, Sally, Kilty, Iain, McKeever, Tricia M., Shrine, Nick, Cook, James P., Patel, Shrina, Spector, Tim D., Hollox, Edward J., Hall, Ian P. and Tobin, Martin D. (2014) Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction. PLoS Genetics, 10 (5). e1004314/1-e1004314/14. ISSN 1553-7404 Portelli, Michael, Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H. and Sayers, Ian (2014) Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB Journal, 28 (2). pp. 923-934. ISSN 0892-6638 Portelli, Michael A., Siedlinski, Mateusz, Stewart, Ceri E., Postma, Dirkje S., Nieuwenhuis, Maartje A., Vonk, Judith M., Nurnberg, Peter, Altmuller, Janine, Moffatt, M.F., Wardlaw, Andrew J., Parker, Stuart G., Connolly, Martin J., Koppelman, Gerard H. and Sayers, Ian (2014) Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels. FASEB Journal, 28 (2). pp. 923-934. ISSN 0892-6638 Ahuja, Sunil K., Wain, Louise V., Odenthal-Hesse, Linda, Abujaber, Razan, Sayers, Ian, Beardsmore, Caroline, Gaillard, Erol A., Chappell, Sally, Dogaru, Cristian M., McKeever, Tricia M., Guetta-Baranes, Tamar, Kalsheker, Noor, Kuehni, Claudia E., Hall, Ian P., Tobin, Martin D. and Hollox, Edward J. (2014) Copy number variation of the beta-defensin genes in Europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma. PLoS ONE, 9 (1). e84192/1-e84192/8. ISSN 1932-6203 Tulah, Asif S., Holloway, John W. and Sayers, Ian (2013) Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children. BMC Medical Genetics, 14 (100). ISSN 1471-2350 Obeidat, Ma’en, Miller, Suzanne, Probert, Kelly, Billington, Charlotte K., Henry, Amanda P., Hodge, Emily, Nelson, Carl P., Stewart, Ceri E., Swan, Caroline, Wain, Louise V., Soler Artigas, María, Melén, Erik, Ushey, Kevin, Hao, Ke, Lamontagne, Maxime, Bossé, Yohan, Postma, Dirkje S., Tobin, Martin D., Sayers, Ian and Hall, Ian P. (2013) GSTCD and INTS12 regulation and expression in the human lung. PLoS ONE, 8 (9). e74630/1-e74630/16. ISSN 1932-6203 Hodge, Emily, Nelson, Carl P., Miller, Suzanne, Billington, Charlotte K., Stewart, Ceri E., Swan, Caroline, Malarstig, Anders, Henry, Amanda P., Gowland, Catherine, Melén, Erik, Hall, Ian P. and Sayers, Ian (2013) HTR4 gene structure and altered expression in the developing lung. Respiratory Research, 14 (77). pp. 1-13. ISSN 1465-9921 Tulah, Asif S., Beghé, Bianca, Barton, Sheila J., Holloway, John W. and Sayers, Ian (2012) Leukotriene B4 receptor locus gene characterisation and association studies in asthma. BMC Medical Genetics, 13 (Novemb). 11/1-11/11. ISSN 1471-2350 Wan, Y.I., Shrine, N.R.G., Soler Artigas, M., Wain, L.V., Blakey, J.D., Moffatt, M.F., Bush, A., Chung, K. F., Cookson, W.O.C.M., Strachan, D.P., Heaney, L., Al-Momani, B.A.H., Mansur, A.H., Manney, S., Thomson, N.C., Chaudhuri, R., Brightling, C.E., Bafadhel, M., Singapuri, A., Niven, R., Simpson, A., Holloway, J.W., Howarth, P.H., Hui, J., Musk, A.W., James, A.L., Brown, M.A., Baltic, S., Ferreira, M.A.R., Thompson, P.J., Tobin, M.D., Sayers, Ian and Hall, Ian P. (2012) Genome-wide association study to identify genetic determinants of severe asthma. Thorax, 67 (9). pp. 762-768. ISSN 0040-6376 Portelli, Michael A. and Sayers, Ian (2012) Genetic basis for personalized medicine in asthma. Expert Review of Respiratory Medicine, 6 (2). pp. 223-236. ISSN 1747-6348 |