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Number of items: 13.

Article

Li, Zhihua, Wu, Wendy W., Sheng, Jiansong, Tran, Phu N., Wu, Min, Ranolph, Aaron, Johnstone, Ross H., Mirams, Gary R., Kuryshev, Yuri, Kramer, James, Wu, Caiyun, Crumb, William J. and Strauss, David G. (2018) Assessment of an in silico mechanistic model for proarrhythmia risk prediction under the CiPA initiative. Clinical Pharmacology & Therapeutics . ISSN 0009-9236 (In Press)

Bowler, Louise A., Gavaghan, David J., Mirams, Gary R. and Whiteley, Jonathan P. (2018) Representation of multiple cellular phenotypes within tissue-level simulations of cardiac electrophysiology. Bulletin of Mathematical Biology . ISSN 0092-8240 (In Press)

Daly, Aidan C., Clerx, Michael, Beattie, Kylie A., Cooper, Jonathan, Gavaghan, David J. and Mirams, Gary R. (2018) Reproducible model development in the Cardiac Electrophysiology Web Lab. Progress in Biophysics and Molecular Biology . ISSN 0079-6107

Beattie, Kylie, Hill, Adam P., Bardenet, Rémi, Cui, Yi, Vandenberg, Jamie I., Gavaghan, David J., de Boer, Teun P. and Mirams, Gary R. (2018) Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics. Journal of Physiology, 596 (10). pp. 1813-1828. ISSN 1469-7793

Samanta, Krishna, Mirams, Gary R. and Parekh, Anant B. (2018) Sequential forward and reverse transport of the Na+ Ca2+ exchanger generates Ca2+ oscillations within mitochondria. Nature Communications, 9 . 156/1-156/10. ISSN 2041-1723

Lei, Chon-Lok, Wang, Ken, Clerx, Michael, Johnstone, Ross H., Hortigon-Vinagre, Maria P., Zamora, Victor, Allan, Andrew, Smith, Godfrey L., Gavaghan, David J., Mirams, Gary R. and Polonchuk, Liudmila (2017) Tailoring mathematical models to stem-cell derived cardiomyocyte lines can improve predictions of drug-induced changes to their electrophysiology. Frontiers in Physiology, 8 . 986/1-986/13. ISSN 1664-042X

Ligneau, Xavier, Shah, Rashmi R., Berrebi-Bertrand, Isabelle, Mirams, Gary R., Robert, Philippe, Landais, Laurent, Maison-Blanche, Pierre, Faivre, Jean-François, Lecomte, Jeanne-Marie and Schwartz, Jean-Charles (2017) Nonclinical cardiovascular safety of pitolisant: comparing International Conference on Harmonization S7B and Comprehensive in vitro Pro-arrhythmia Assay initiative studies. British Journal of Pharmacology, 174 . pp. 4449-4463. ISSN 1476-5381

Chang, Kelly, Dutta, Sara, Mirams, Gary R., Beattie, Kylie, Sheng, Jiansong, Tran, Phu N., Wu, Min, Wu, Wendy W., Colatsky, Thomas, Strauss, David G. and Li, Zhihua (2017) Uncertainty quantification reveals the importance of data variability and experimental design considerations for in silico proarrhythmia risk assessment. Frontiers in Physiology, 8 . 917/1-917/12. ISSN 1664-042X

McMillan, Beth, Gavaghan, David J. and Mirams, Gary R. (2017) Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator. Toxicology Research, 6 . pp. 912-921. ISSN 2045-452X

Hartung, Thomas, FitzGerald, Rex E., Jennings, Paul, Mirams, Gary R., Peitsch, Manuel C., Rostami-Hodjegan, Amin, Shah, Imran, Wilks, Martin F. and Sturla, Shana J. (2017) Systems toxicology: real world applications and opportunities. Chemical Research in Toxicology, 30 (4). pp. 870-882. ISSN 1520-5010

Johnstone, Ross H., Bardenet, Rémi, Gavaghan, David J. and Mirams, Gary R. (2017) Hierarchical Bayesian inference for ion channel screening dose-response data. Wellcome Open Research, 1 . 6/1-6/22. ISSN 2398-502X

Aston, Daniel, Capel, Rebecca A., Ford, Kerrie L., Christian, Helen C., Mirams, Gary R., Rog-Zielinska, Eva A., Kohl, Peter, Galione, Antony, Burton, Rebecca A.B. and Terrar, Derek A. (2017) High resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with acidic stores (lysosomes) in the heart. Scientific Reports, 7 . 40620/1-40620/15. ISSN 2045-2322

Thesis (University of Nottingham only)

Mirams, Gary R. (2008) Subcellular phenomena in colorectal cancer. PhD thesis, University of Nottingham.

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