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2018

Alagesan, Swathi, Hanko, Erik K.R., Malys, Naglis, Ehsaan, Muhammad, Winzer, Klaus and Minton, Nigel P. (2018) Functional genetic elements for controlling gene expression in Cupriavidus necator H16. Applied and Environmental Microbiology . ISSN 1098-5336 (In Press)

Dalwadi, Mohit P., Wang, Yanming, King, John R. and Minton, Nigel P. (2018) Upscaling diffusion through first-order volumetric sinks: a homogenization of bacterial nutrient uptake. SIAM Journal on Applied Mathematics, 78 (3). pp. 1300-1329. ISSN 1095-712X

Hanko, Erik K.R., Minton, Nigel P. and Malys, Naglis (2018) A transcription factor-based biosensor for detection of itaconic acid. ACS Synthetic Biology . ISSN 2161-5063 (In Press)

Little, Gareth T., Willson, Benjamin J., Heap, John T., Winzer, Klaus and Minton, Nigel P. (2018) The butanol producing microbe Clostridium beijerinckii NCIMB 14988 manipulated using forward and reverse genetic tools. Biotechnology Journal . ISSN 1860-7314 (In Press)

Schatschneider, Sarah, Abdelrazig, Salah M.A., Safo, Laudina, Henstra, Anne M., Millat, Thomas, Kim, Dong-Hyun, Winzer, Klaus, Minton, Nigel P. and Barrett, David A. (2018) Quantitative isotope-dilution high-resolution-mass-apectrometry analysis of multiple intracellular metabolites in Clostridium autoethanogenum with uniformly 13C-labeled standards derived from Spirulina. Analytical Chemistry, 90 (7). pp. 4470-4477. ISSN 1520-6882

Dalwadi, Mohit P., Garavaglia, Marco, Webb, Joseph P., King, John R. and Minton, Nigel P. (2018) Applying asymptotic methods to synthetic biology: modelling the reaction kinetics of the mevalonate pathway. Journal of Theoretical Biology, 439 . pp. 39-49. ISSN 1095-8541

Humphreys, Christopher M. and Minton, Nigel P. (2018) Advances in metabolic engineering in the microbial production of fuels and chemicals from C1 gas. Current Opinion in Biotechnology, 50 . pp. 174-181. ISSN 1879-0429

Alagesan, Swathi, Minton, Nigel P. and Malys, Naglis (2018) 13C-assisted metabolic flux analysis to investigate heterotrophic and mixotrophic metabolism in Cupriavidus necator H16. Metabolomics, 14 (9). pp. 1-9. ISSN 1573-3890

2017

Grosse-Honebrink, Alexander, Schwarz, Katrin, Wang, Hengzheng, Minton, Nigel P. and Zhang, Ying (2017) Improving gene transfer in Clostridium pasteurianum through the isolation of rare hypertransformable variants. Anaerobe, 48 . pp. 203-205. ISSN 1095-8274

Dalwadi, Mohit P., King, John R. and Minton, Nigel P. (2017) Multi-timescale analysis of a metabolic network in synthetic biology: a kinetic model for 3-hydroxypropionic acid production via beta-alanine. Journal of Mathematical Biology . ISSN 1432-1416

Mordaka, Pawel M., Hall, Stephen J., Minton, Nigel P. and Stephens, Gill (2017) Recombinant expression and characterisation of the oxygen-sensitive 2-enoate reductase from Clostridium sporogenes. Microbiology . pp. 1-11. ISSN 1465-2080

Griffin, R. and Minton, Nigel P. (2017) Exposing hidden putative lipoproteins in Clostridium difficile. In: ClostPath 10th International Conference on the Molecular Biology and Pathogenesis of the Clostrida, 7-10 Aug 2017, Ann Arbor, Michigan, USA.

Hanko, Erik K.R., Minton, Nigel P. and Malys, Naglis (2017) Characterisation of a 3-hydroxypropionic acid-inducible system from Pseudomonas putida for orthogonal gene expression control in Escherichia coli and Cupriavidus necator. Scientific Reports, 7 . 1724/1-1724/13. ISSN 2045-2322

Schwarz, Katrin, Grosse-Honebrink, Alexander, Derecka, Kamila, Rotta, Carlo, Zhang, Ying and Minton, Nigel P. (2017) Towards improved butanol production through targeted genetic modification of Clostridium pasteurianum. Metabolic Engineering . ISSN 1096-7184

Liew, Fungmin, Henstra, Anne M., Kӧpke, Michael, Winzer, Klaus, Simpson, Sean D. and Minton, Nigel P. (2017) Metabolic engineering of Clostridium autoethanogenum for selective alcohol production. Metabolic Engineering, 40 . pp. 104-114. ISSN 1096-7184

Bilverstone, T.W., Kinsmore, N.L., Minton, Nigel P. and Kuehne, Sarah A. (2017) Development of Clostridium difficile R20291ΔPaLoc model strains and in vitro methodologies reveals CdtR is required for the production of CDT to cytotoxic levels. Anaerobe, 44 . pp. 51-54. ISSN 1095-8274

2016

Walker, David J.F., Heap, John T., Winzer, Klaus and Minton, Nigel P. (2016) A genetic assay for gene essentiality in Clostridium. Anaerobe, 42 . pp. 40-43. ISSN 1095-8274

Stevenson, Emma C., Major, Giles A., Spiller, Robin C., Kuehne, Sarah A. and Minton, Nigel P. (2016) Co-infection and emergence of rifamycin resistance during a recurrent Clostridium difficile infection. Journal of Clinical Microbiology, 54 (11). pp. 2689-2694. ISSN 1098-660X

Minton, Nigel P., Ehsaan, Muhammad, Humphreys, Christopher M., Little, Gareth T., Baker, Jonathan, Henstra, Anne M., Liew, Fungmin, Kelly, Michelle, Sheng, Lili, Schwarz, Katrin and Zhang, Ying (2016) A roadmap for gene system development in Clostridium. Anaerobe, 41 . pp. 104-112. ISSN 1095-8274

Collery, Mark M., Kuehne, Sarah A., McBride, Shonna M., Kelly, Michelle L., Monot, Marc, Cockayne, Alan, Dupuy, Bruno and Minton, Nigel P. (2016) What's a SNP between friends: the influence of single nucleotide polymorphisms on virulence and phenotypes of Clostridium difficile strain 630 and derivatives. Virulence . ISSN 2150-5608

Minton, Nigel P. and Burbidge, Alan (2016) SBRC-Nottingham: Sustainable Routes to Platform Chemicals from C1 Wastes Gases. Biochemical Society Transactions . ISSN 0300-5127 (In Press)

Liew, Fungmin, Henstra, Anne M., Winzer, Klaus, Kopke, Michael, Simpson, Sean D. and Minton, Nigel P. (2016) Insights into CO2 fixation pathway of Clostridium autoethanogenumby targeted mutagenesis. mBio, 7 (3). e00427-16. ISSN 2150-7511

Willson, Benjamin J., Kovács, Katalin, Wilding-Steele, Tom, Markus, Robert, Winzer, Klaus and Minton, Nigel P. (2016) Production of a functional cell wall-anchored minicellulosome by recombinant Clostridium acetobutylicum ATCC 824. Biotechnology for Biofuels, 9 (1). p. 109. ISSN 1754-6834

Zhang, Ying, Xu, Shu, Chai, Changsheng, Yang, Sheng, Jiang, Weihong, Minton, Nigel P. and Gu, Yang (2016) Development of an inducible transposon system for efficient random mutagenesis in Clostridium acetobutylicum. FEMS Microbiology Letters, 363 (8). fnw065/1-fnw065/7. ISSN 1574-6968

2015

Humphreys, Christopher M., McLean, Samantha, Schatschneider, Sarah, Millat, Thomas, Henstra, Anne M., Annan, Florence J., Breitkopf, Florence, Pander, Bart, Piatek, Pawel, Rowe, Peter, Wichlacz, Alexander T., Woods, Craig, Norman, Rupert, Blom, Jochen, Goesman, Alexander, Hodgman, Charlie, Barrett, David, Thomas, Neil R., Winzer, Klaus and Minton, Nigel P. (2015) Whole genome sequence and manual annotation of Clostridium autoethanogenum, an industrially relevant bacterium. BMC Genomics, 16 . 1085/1-1085/10. ISSN 1471-2164

2014

Millat, Thomas, Voigt, Christine, Janssen, Holger, Cooksley, Clare M., Winzer, Klaus, Minton, Nigel P., Bahl, Hubert, Fischer, Ralf-Jörg and Wolkenhauer, Olaf (2014) Coenzyme A-transferase-independent butyrate re-assimilation in Clostridium acetobutylicum - evidence from a mathematical model. Applied Microbiology and Biotechnology, 98 (21). pp. 9059-9072. ISSN 1432-0614

2013

Baban, Soza T., Kuehne, Sarah A., Barketi-Klai, Amira, Cartman, Stephen T., Kelly, Michelle L., Hardie, Kim R., Kansau, Imad, Collignon, Anne and Minton, Nigel P. (2013) The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain. PLoS ONE, 8 (9). e73026. ISSN 1932-6203

Baban, Soza T., Kuehne, Sarah A., Barketi-Klai, Amira, Cartman, Stephen T., Kelly, Michelle L., Hardie, Kim R., Kansau, Imad, Collignon, Anne and Minton, Nigel P. (2013) The role of flagella in Clostridium difficile pathogenesis: comparison between a non-epidemic and an epidemic strain. PLoS ONE, 8 (9). e73026. ISSN 1932-6203

Kovacs, Katalin, Willson, Benjamin J., Schwarz, Katrin, Heap, John T., Jackson, Adam, Bolam, David N., Winzer, Klaus and Minton, Nigel P. (2013) Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824. Biotechnology for Biofuels, 6 (117). ISSN 1754-6834

Kuehne, Sarah A., Collery, Mark M., Kelly, Michelle L., Cartman, Stephen T., Cockayne, Alan and Minton, Nigel P. (2013) Importance of Toxin A, Toxin B, and CDT in virulence of an epidemic Clostridium difficile strain. Journal of Infectious Diseases, 209 (1). pp. 83-86. ISSN 1537-6613

Jafari, Nazilla V., Kuehne, Sarah A., Bryant, Clare E., Elawad, Mamoun, Wren, Brendan W., Minton, Nigel P., Allan, Elaine and Bajaj-Elliott, Mona (2013) Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s). PLoS ONE, 8 (7). e69846/1-e69846/10. ISSN 1932-6203

Jabbari, Sara, Steiner, Elisabeth, Heap, John T., Winzer, Klaus, Minton, Nigel P. and King, John R. (2013) The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum. Mathematical Biosciences, 243 (2). pp. 223-239. ISSN 0025-5564

Zhang, Zhen, Korkeala, Hannu, Dahlsten, Elias, Sahala, Elina, Heap, John T., Minton, Nigel P. and Linström, Miia (2013) Two-component signal transduction system CBO0787/ CBO0786 represses transcription from botulinum neurotoxin promoters in Clostridium botulinum ATCC 3502. PloS Pathogens, 9 (3). e1003252. ISSN 1553-7374

Ng, Yen K., Ehsaan, Muhammad, Philip, Sheryl, Collery, Mark M., Janoir, Clare, Collignon, Anne, Cartman, Stephen T. and Minton, Nigel P. (2013) Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles. PLoS ONE, 8 (2). 13/1-13/13. ISSN 1932-6203

Dapa, Tanja, Leuzzi, Rosanna, Ng, Yen K., Baban, Soza T., Adamo, Roberto, Kuehne, Sarah A., Scarselli, Maria, Minton, Nigel P., Serruto, David and Unnikrishnan, Meera (2013) Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile. Journal of Bacteriology, 195 (3). pp. 545-555. ISSN 0021-9193

Fendri, Imen, Abdou, Laetitia, Trotter, Valentine, Dedieu, Luc, Maamar, Hédia, Minton, Nigel P. and Tardif, Chantal (2013) Regulation of cel genes of C. cellulolyticum: identification of GlyR2, a transcriptional regulator regulating cel5D gene expression. PLoS ONE, 8 (1). e44708. ISSN 1932-6203

2012

Heeg, Daniela, Burns, David A., Cartman, Stephen T. and Minton, Nigel P. (2012) Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts. PLoS ONE, 7 (2). e32381/1-e32381/9. ISSN 1932-6203

Heap, John T., Ehsaan, Muhammad, Cooksley, Clare M., Ng, Yen-Kuan, Cartman, Stephen T., Winzer, Klaus and Minton, Nigel P. (2012) Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker. Nucleic Acids Research, 40 (8). 10/1-10/10. ISSN 0305-1048

2011

Kuehne, Sarah A., Cartman, Stephen T. and Minton, Nigel P. (2011) Both, toxin A and toxin B, are important in Clostridium difficile infection. Gut Microbes, 2 (4). pp. 252-255. ISSN 1949-0976