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2018

Bridge, Jack Christopher, Amer, Mahetab H., Morris, Gavin E., Martin, N.R.W., Player, Darren J., Knox, Alan J., Aylott, Jonathan W., Lewis, Mark P. and Rose, Felicity R.A.J. (2018) Electrospun gelatin-based scaffolds as a novel 3D platform to study the function of contractile smooth muscle cells in vitro. Biomedical Physics & Engineering Express, 4 (4). 045039/1-045039/14. ISSN 2057-1976

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2018) Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1861 (5). pp. 463-472. ISSN 0006-3002

Clifford, Rachel L., Fishbane, Nick, Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., Fisher, Andrew J., Brandsma, Corry-Anke, Nair, Parameswaran, Kobor, Michael S., Hackett, Tillie-Louise and Knox, Alan J. (2018) Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD. Clinical Epigenetics, 10 (1). p. 32. ISSN 1868-7083

Deacon, Karl and Knox, Alan J. (2018) PINX1 and TERT are required for TNF-α-induced airway smooth muscle chemokine gene expression. Journal of Immunology, 200 (4). pp. 1283-1294. ISSN 1550-6606

2017

Coward, William R., Brand, Oliver J., Pasini, Alice, Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2017) Interplay between EZH2 and G9a regulates CXCL10 gene repression in idiopathic pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology . ISSN 1535-4989

Htwe, Su S., Cha, Byung H., Yue, Kan, Khademhosseini, Ali, Knox, Alan J. and Ghaemmaghami, Amir M. (2017) Role of ROCK isoforms in regulation of stiffness induced myofibroblast differentiation in lung fibrosis. American Journal of Respiratory Cell and Molecular Biology, 56 (6). ISSN 1535-4989

Barr, Helen L., Halliday, Nigel, Barrett, David A., Williams, Paul, Forrester, Doug L., Peckham, Daniel, Williams, Kate, Smyth, Alan R., Honeybourne, David, Whitehouse, Joanna L., Nash, Edward F., Dewar, Jane, Clayton, Andrew, Knox, Alan J., Cámara, Miguel and Fogarty, Andrew W. (2017) Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study. Journal of Cystic Fibrosis, 16 (2). pp. 230-238. ISSN 1873-5010

2016

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2016) Effect of epigenetic inhibitors on lung fibroblast phenotype change in idiopathic pulmonary fibrosis. Thorax, 71 (Supp3). A32. ISSN 1468-3296

Pasini, Alice, Brand, Oliver J., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2016) Effect of epigenetic inhibitors on lung fibroblast phenotype change in idiopathic pulmonary fibrosis. In: British Thoracic Society Winter Meeting 2016, 7-9 Dec 2016, London. (Unpublished)

Brand, Oliver J., Pasini, Alice, Habgood, Antony, Knox, Alan J., Jenkins, Gisli and Pang, Linhua (2016) S52 Suberanilohydroxamic acid (SAHA) inhibits collagen deposition in a transforming growth factor β1-driven precision cut lung slice (PCLS) model of pulmonary fibrosis. Thorax, 71 (Supp 3). A31. ISSN 1468-3296

John, Alison, E., Wilson, Michael, R., Habgood, Anthony, Porte, Joanne, Tatler, Amanda L., Stavrou, Anastasios, Miele, Gino, Jolly, Lisa, Knox, Alan J., Takata, Masao, Offermanns, Stefan and Jenkins, R. Gisli (2016) Loss of epithelial Gq and G11 signaling inhibits TGFβ production but promotes IL-33–mediated macrophage polarization and emphysema. Science Signaling, 9 (451). ra104/1. ISSN 1937-9145

Brand, Oliver J., Pasini, Alice, Habgood, Antony, Knox, Alan J., Jenkins, Gisli and Pang, Linhua (2016) Suberanilohydroxamic acid (SAHA) inhibits collagen deposition in a transforming growth factor β1-driven precision cut lung slice (PCLS) model of pulmonary fibrosis. In: British Thoracic Society Winter Meeting 2016, 7-9 Dec 2016, London, UK. (Unpublished)

Anderson, J.R., Mortimer, K., Pang, Linhua, Smith, K.M., Bailey, H., Hodgson, D.B., Shaw, Dominick E., Knox, Alan J. and Harrison, Timothy W. (2016) Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial. PLoS ONE, 11 (8). e0160257/1-e0160257/15. ISSN 1932-6203

Poghosyan, Anna, Patel, Jamie K., Clifford, Rachel L. and Knox, Alan J. (2016) Epigenetic dysregulation of interleukin 8 (CXCL8) hypersecretion in cystic fibrosis airway epithelial cells. Biochemical and Biophysical Research Communications, 476 (4). pp. 431-437. ISSN 1090-2104

2015

Forrester, Doug L., Knox, Alan J., Smyth, Alan R., Barr, Helen L., Simms, Rebecca, Pacey, Sarah J., Pavord, Ian D., Honeybourne, David, Dewar, Jane, Clayton, Andy and Fogarty, Andrew W. (2015) Glutamine supplementation in cystic fibrosis: a randomized placebo-controlled trial. Pediatric Pulmonology, 51 (3). pp. 253-257. ISSN 1099-0496

Shaw, Dominick E., Sousa, Ana R., Fowler, Stephen J., Fleming, Louise J., Roberts, Graham, Corfield, Julie, Pandis, Ioannis, Bansal, Aruna T., Bel, Elisabeth H., Auffray, Charles, Compton, Chris H., Bisgaard, Hans, Bucchioni, Enrica, Caruso, Massimo, Chanez, Pascal, Dahlen, Barbro, Dahlen, Sven-Erik, Dyson, Kerry, Frey, Urs, Geiser, Thomas, Gerhardsson de Verdier, Maria, Gibeon, David, Guo, Yi-ke, Hashimoto, Simone, Hedlin, Gunilla, Jeyasingham, Elizabeth, Hekking, Pieter-Paul W., Higenbottam, Tim, Horváth, Ildikó, Knox, Alan J., Krug, Norbert, Erpenbeck, Veit J., Larsson, Lars X., Lazarinis, Nikos, Matthews, John G., Middelveld, Roelinde, Montuschi, Paolo, Musial, Jacek, Myles, David, Pahus, Laurie, Sandström, Thomas, Seibold, Wolfgang, Singer, Florian, Strandberg, Karin, Vestbo, Jorgen, Vissing, Nadja, von Garnier, Christophe, Adcock, Ian M., Wagers, Scott, Rowe, Anthony, Howarth, Peter, Wagener, Ariane H., Djukanovic, Ratko, Sterk, Peter J. and Chung, Kian Fan (2015) Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. European Respiratory Journal, 46 (5). pp. 1308-1321. ISSN 1399-3003

Barr, Helen L., Halliday, Nigel, Cámara, Miguel, Barrett, David A., Williams, Paul, Forrester, Doug L., Simms, Rebecca, Smyth, Alan R., Honeybourne, David, Whitehouse, Joanna L., Nash, Edward F., Dewar, Jane, Clayton, Andrew, Knox, Alan J. and Fogarty, Andrew W. (2015) Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis. European Respiratory Journal, 46 (4). pp. 1046-1054. ISSN 1399-3003

Prayle, A.P., Jain, K., Touw, D.J., Koch, B.C.P., Knox, Alan J., Watson, A. and Smyth, Alan R. (2015) The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: a randomised comparison. Journal of Cystic Fibrosis . ISSN 1873-5010

John, Michelle, Cockcroft, John R., McKeever, Tricia M., Coward, William R., Shale, Dennis J., Johnson, Simon R., Thornton, Jim, Harrison, Timothy W., Knox, Alan J. and Bolton, Charlotte E. (2015) Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial. International Journal of Chronic Obstructive Pulmonary Disease, 10 (1). pp. 211-221. ISSN 1178-2005

2014

Coward, William R., Feghali-Bostwick, Carol A., Jenkins, Gisli, Knox, Alan J. and Pang, Linhua (2014) A central role for G9a and EZH2 in the epigenetic silencing of cyclooxygenase-2 in idiopathic pulmonary fibrosis. FASEB Journal, 28 (7). pp. 3183-3196. ISSN 0892-6638

2013

Forrester, Doug L., Knox, Alan J., Smyth, Alan R. and Fogarty, Andrew W. (2013) Measures of body habitus are associated with lung function in adults with cystic fibrosis: a population-based study. Journal of Cystic Fibrosis, 12 (3). pp. 284-289. ISSN 1873-5010