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Blair, Gordon W., Appleton, Jason P., Law, Zhe Kang, Doubal, Fergus, Flaherty, Katie, Dooley, Richard, Shuler, Kirsten, Richardson, Carla, Hamilton, Iona, Shi, Yulu, Stringer, Michael, Boyd, Julia, Thrippleton, Michael J., Sprigg, Nikola, Bath, Philip M.W. and Wardlaw, Joanna M. (2018) Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination. International Journal of Stroke, 13 (5). pp. 530-538. ISSN 1747-4949

Bath, Philip M.W., Appleton, Jason P., Krishnan, Kailash and Sprigg, Nikola (2018) Blood pressure in acute stroke: to treat or not to treat - that is still the question. Stroke, 49 (7). pp. 1784-1790. ISSN 1524-4628

Scutt, Polly, Appleton, Jason P., Dixon, Mark, Woodhouse, Lisa J., Sprigg, Nikola, Wardlaw, Joanna M., Montgomery, Alan A., Pocock, Stuart J. and Bath, Philip M.W. (2018) Statistical analysis plan for the ‘Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2)’. European Stroke Journal, 3 (2). pp. 193-196. ISSN 2396-9881

Sprigg, Nikola, Flaherty, Katie, Appleton, Jason P., Al-Shahi Salman, Rustam, Bereczki, Daniel, Beridze, M., Christensen, Hanne, Ciccone, Alfonso, Collins, Ronan, Czlonkowska, Anna, Dineen, Robert A., Duley, Lelia, Egea-Guerrero, Juan Jose, England, Timothy J., Krishnan, Kailash, Laska, Ann Charlotte, Law, Zhe Kang, Ozturk, Serefnur, Pocock, Stuart J., Roberts, Ian, Robinson, Thompson G., Roffe, Christine, Seiffge, David, Scutt, Polly, Thanabalan, Jegan, Werring, David, Whynes, David and Bath, Philip M. (2018) Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. The Lancet . ISSN 1474-547X

Bath, Philip M.W., Woodhouse, Lisa J., Appleton, Jason P., Beridze, M., Christensen, Hanne, Dineen, Robert A., Duley, Lelia, England, Timothy J., Flaherty, Katie, Havard, Diane, Heptinstall, Stan, James, Marilyn, Krishnan, Kailash, Markus, H.S., Montgomery, Alan A., Pocock, Stuart J., Randall, Marc, Ranta, A., Robinson, Thompson G., Scutt, Polly, Venables, Graham S. and Sprigg, Nikola (2018) Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial. Lancet, 391 (10123). pp. 850-859. ISSN 1474-547X

Armstrong, Stephanie, Langlois, Adele, Laparidou, Despina, Dixon, Mark, Appleton, Jason P., Bath, Philip M.W., Snooks, Helen Anne and Siriwardena, A. Niroshan (2017) Assessment of consent models as an ethical consideration in the conduct of prehospital ambulance randomised controlled clinical trials: a systematic review. BMC Medical Research Methodology, 17 (1). 142/1-142/10. ISSN 1471-2288

Appleton, Jason P., Scutt, Polly, Dixon, Mark, Howard, Harriet, Haywood, Lee, Havard, Diane, Hepburn, Trish, England, Timothy J., Sprigg, Nikola, Woodhouse, Lisa J., Wardlaw, Joanna M., Montgomery, Alan A., Pocock, Stuart J. and Bath, Philip M.W. (2017) Ambulance-delivered transdermal glyceryl trinitrate versus sham for ultra-acute stroke: rationale, design and protocol for the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2) trial (ISRCTN26986053). International Journal of Stroke . ISSN 1747-4949

Bath, Philip M.W., Appleton, Jason P., Beridze, M., Christensen, Hanne, Dineen, Robert A., Duley, Lelia, England, Timothy J., Heptinstall, Stan, James, Marilyn, Krishnan, Kailash, Markus, H.S., Pocock, Stuart J., Ranta, A., Robinson, Thompson G., Flaherty, Katie, Scutt, Polly, Venables, G., Woodhouse, Lisa J. and Sprigg, Nikola (2017) Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial. International Journal of Stroke, 12 (5). pp. 524-538. ISSN 1747-4949

Appleton, Jason P., Scutt, Polly, Sprigg, Nikola and Bath, Philip M.W. (2017) Hypercholesterolaemia and vascular dementia. Clinical Science, 131 (14). pp. 1561-1578. ISSN 1470-8736

Bath, Philip M.W., Krishnan, Kailash and Appleton, Jason P. (2017) Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke. Cochrane Database of Systematic Reviews (4). CD000398. ISSN 1465-1858

Law, Zhe Kang, Appleton, Jason P., Bath, Philip M.W. and Sprigg, Nikola (2017) Management of acute intracerebral haemorrhage – an update. Clinical Medicine, 17 (2). pp. 166-172. ISSN 1473-4893

Appleton, Jason P., Sprigg, Nikola and Bath, Philip M.W. (2016) Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke. CNS Drugs . ISSN 1179-1934

Bath, Philip M.W., Appleton, Jason P. and Sprigg, Nikola (2016) The Insulin Resistance Intervention after Stroke trial: a perspective on future practice and research. International Journal of Stroke . ISSN 1747-4949

Appleton, Jason P., Sprigg, Nikola and Bath, Philip M.W. (2016) Blood pressure management in acute stroke. Stroke and Vascular Neurology, 1 (2). pp. 72-82. ISSN 2059-8696

Conference or Workshop Item

Dixon, Mark, Scutt, Polly, Appleton, Jason P., Spaight, Robert, Johnson, Roderick, Siriwardena, A. Niroshan and Bath, Philip M.W. (2018) Interim analysis of ambulance logistics and timings in patients recruited into the Rapid intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2). In: 12th UK Stroke Forum Conference (UKSF 2017), 28-30 Nov 2017, Liverpool, UK.

Appleton, Jason P. (2018) The effect of transdermal glyceryl trinitrate on imaging characteristics in acute ischaemic stroke: data from the Efficacy of Nitric Oxide in Stroke trial. In: World Stroke Congress, 17-20 October 2018, Montreal, Canada.

Woodhouse, Lisa J., Flaherty, Katie, Appleton, Jason P., Sprigg, Nikola and Bath, Philip M.W. (2018) Characteristics and outcomes of patients with or without a bleeding event: results from the triple antiplatelets for reducing dependency in ischaemic stroke (TARDIS) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Woodhouse, Lisa J., Appleton, Jason P., Flaherty, Katie, Dineen, Robert A., Sprigg, Nikola and Bath, Philip M. (2018) Impact of atrial fibrillation diagnosis or carotid enderterectomy requirement on outcome in patients from the triple antiplatelets for reducing dependency after ischaemic stroke (TARDIS) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Appleton, Jason P., Blair, Gordon W., Flaherty, Katie, Law, Zhe Kang, Doubal, Fergus, Sprigg, Nikola, Bath, Philip M.W. and Wardlaw, Joanna M. (2018) Peripheral and central haemodynamics in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Appleton, Jason P., Flaherty, Katie, Blair, Gordon W., Law, Zhe Kang, Doubal, Fergus, Sprigg, Nikola, Bath, Philip M. and Wardlaw, Joanna M. (2018) Platelet and haemoglobin levels in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Woodhouse, Lisa J., Flaherty, Katie, Appleton, Jason P., Sprigg, Nikola and Bath, Philip M.W. (2018) Prediction of major bleeding with a S2TOP-BLEED score in acute ischaemic stroke or TIA patients: a sub-study of the TARDIS trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Dixon, Mark, Appleton, Jason P., Scutt, Polly, England, Tim, Havard, Diane, Howard, Harriet, Jarvis, Malcolm, Montgomery, Alan, Pocock, Stuart, Potter, John, Price, Chris, Robinson, Tom, Roffe, Christine, Siriwardena, A. Niro, Sprigg, Nikola, Wardlaw, Joanna M. and Bath, Philip M. (2018) Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2): safety and efficacy of transdermal glyceryl trinitrate, a nitric oxide donor, and of the feasibility of a multicentre ambulance-based stroke trial. In: 4th European Stroke Organisation Conference, ESOC 2018, 16-18 May 2018, Gothenburg, Sweden.

Sprigg, Nikola, Flaherty, Katie, Law, Zhe Kang, Appleton, Jason P., Scutt, Polly, Krishnan, Kailash and Bath, Philip M. (2018) Results from the tranexamic acid for primary intracerebral haemorrhage-2 (TICH-2) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Scutt, Polly, Dixon, Mark, Appleton, Jason P., Howard, Harriet, Havard, Diane, Woodhouse, Lisa J. and Bath, Philip M. (2018) Consent procedures and relationship with outcome in the Rapid Intervention with Glyceryl trinitrate in Hypertensive stroke Trial-2 (RIGHT-2). In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden. (In Press)

Appleton, Jason P., Hedstrom, Amanda, O'Sullivan, Saoirse, May, Jane, Sprigg, Nikola, Bath, Philip M.W. and England, Timothy J. (2018) Serum amyloid protein is associated with outcome following acute ischaemic stroke: data from the REmote ischaemic Conditioning After Stroke Trial (RECAST). In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden. (In Press)