A two-fluid model for tissue growth within a dynamic flow environmentTools O'Dea, Reuben D. and Waters, Sarah L. and Byrne, Helen M. (2008) A two-fluid model for tissue growth within a dynamic flow environment. European Journal of Applied Mathematics, 19 . pp. 607-634. ISSN 0956-7925 Full text not available from this repository.AbstractWe study the growth of a tissue construct in a perfusion bioreactor, focussing on its response to the mechanical environment. The bioreactor system is modelled as a two-dimensional channel containing a tissue construct through which a flow of culture medium is driven. We employ a multiphase formulation of the type presented by G. Lemon, J. King, H. Byrne, O. Jensen and K. Shakesheff in their study (Multiphase modelling of tissue growth using
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