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Waller, Elizabeth Sophie Louise (2024) Investigating the genetic epidemiology of bovine tuberculosis between compatric and contemporaneous badgers and bovines in England. MRes thesis, University of Nottingham.

PDF (Uploading final corrections to MRes thesis submitted August 2024 - now with project ethics numbers amended) (Thesis - as examined) - Repository staff only until 11 December 2026. Subsequently available to Anyone - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader Available under Licence Creative Commons Attribution. Download (5MB)

Abstract

This project aimed to investigate the contemporaneous and compatric incidents of bTB in cattle and badgers in Northern and Southern Edge counties in England and the LRA county of Hertfordshire between 2016 and 2022.

This project used a k-mer genomic comparison technique to analyse a total of 59 badgers and 353 cattle. Amongst the badgers, the most prevalent clade was B6-62 (across both the Northern and Southern Edge studies), followed by B3-11 (all in the Northern Edge badger study). Amongst cattle, clade distribution followed a similar pattern as in badgers, with B3-11 more prevalent in cattle from the Northern Edge counties and B6-62 more prevalent in cattle from the Southern Edge counties.

Most counties had at least one badger in each county did have a strong level of genetic identity with compatric cattle. The exceptions were Derbyshire, East Sussex, and Northamptonshire, where little to no genetic similarity was observed between compatric and contemporaneous cattle, even despite sharing the same clades.

Item Type:	Thesis (University of Nottingham only) (MRes)
Supervisors:	Blanchard, Adam Bennett, Malcolm
Keywords:	bovine TB, cattle, badgers, genetic epidemiology
Subjects:	S Agriculture > SF Animal culture
Faculties/Schools:	UK Campuses > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Item ID:	79399
Depositing User:	Waller, Elizabeth
Date Deposited:	11 Dec 2024 04:40
Last Modified:	11 Dec 2024 04:40
URI:	https://eprints.nottingham.ac.uk/id/eprint/79399

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