An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta

Chung, Chee Yap and Yang, Jie and He, Jun and Yang, Xiaogang and Hubbard, Richard and Ji, Dongsheng (2021) An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta. Science of The Total Environment, 779 . p. 146427. ISSN 00489697

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Abstract

Lung cancer (LC) mortality, as one of the top cancer deaths in China, has been associated with increased levels of exposure to ambient air pollutants. In this study, different lag times on weekly basis were applied to study the association of air pollutants (PM2.5, PM10, and NO2) and LC mortality in Ningbo, and in subpopulations at different age groups and genders. Furthermore, seasonal variations of pollutant concentrations and meteorological variables (temperature, relative humidity, and wind speed) were analysed. A generalised additive model (GAM) using Poisson regression was employed to estimate the effect of single pollutant model on LC mortality in Yangtze River Delta using Ningbo as a case study. It was reported that there were statistically significant relationships between lung cancer mortality and air pollutants. Increases of 6.2% (95% confidence interval [CI]: 0.2% to 12.6%) and 4.3% (95% CI: 0.1% to 8.5%) weekly total LC mortality with a 3-week lag time were linked to each 10 μg/m3 increase of weekly average PM2.5 and PM10 respectively. The association of air pollutants (PM2.5, PM10 and NO2) and LC mortality with a 3-week lag time was also found statistically significant during periods of low temperature (T < 18 °C), low relative humidity (H < 73.7%) and low wind speed (u < 2.8 m/s), respectively. The female population was found to be more susceptible to the exposure to air pollution than the male population. In addition, the population with an age of 50 years or above was shown to be more sensitive to ambient air pollutant. These outcomes indicated that increased risk of lung cancer mortality was evidently linked to exposure to ambient air pollutant on a weekly basis. The impact of weekly variation on the LC mortality and air pollutant levels should be considered in air pollution-related health burden analysis.

Item Type: Article
Keywords: Ambient air pollution; Lag time; Lung cancer mortality; Meteorological factors; Modelling; Yangtze River Delta
Schools/Departments: University of Nottingham Ningbo China > Faculty of Science and Engineering > Department of Chemical and Environmental Engineering
University of Nottingham Ningbo China > Faculty of Science and Engineering > School of Mathematical Sciences
University of Nottingham Ningbo China > Faculty of Science and Engineering > Department of Mechanical, Materials and Manufacturing Engineering
Identification Number: https://doi.org/10.1016/j.scitotenv.2021.146427
Depositing User: Wu, Cocoa
Date Deposited: 07 May 2021 08:46
Last Modified: 07 May 2021 08:46
URI: http://eprints.nottingham.ac.uk/id/eprint/65287

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