The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic responseTools Barone, Giancarlo and Arora, Arvind and Ganesh, Anil and Abdel-Fatah, Tarek and Moseley, Paul and Ali, Reem and Chan, Stephen Y.T. and Savva, Constantinos and Schiavone, Kristina and Carmell, Natasha and Myers, Katie N. and Rakha, Emad A. and Madhusudan, Srinivasan and Collis, Spencer J. (2018) The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response. Oncotarget, 9 . pp. 29508-29524. ISSN 1949-2553 Full text not available from this repository.
Official URL: http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=25686
AbstractBackground: Cyclin-Dependent Kinases (CDKs) are established anti-cancer drug targets and a new generation of CDK inhibitors are providing clinical benefits to a sub-set of breast cancer patients. We have recently shown that human CDK18 promotes efficient cellular responses to replication stress. In the current study, we have investigated the clinicopathological and functional significance of CDK18 expression levels in breast cancers.
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