Macrophage-derived interleukin-1beta promotes human breast cancer cell migration and lymphatic adhesion in vitroTools Storr, Sarah J. and Safuan, Sabreena and Ahmad, Narmeen and El-Refaee, Mohammed and Jackson, Andrew M. and Martin, Stewart G. (2017) Macrophage-derived interleukin-1beta promotes human breast cancer cell migration and lymphatic adhesion in vitro. Cancer Immunology, Immunotherapy . ISSN 0340-7004
AbstractLymphovascular invasion (LVI), encompassing blood and lymphatic vessel invasion, is an important event in tumourigenesis. Macrophages within the tumour microenvironment are linked to the presence of LVI and angiogenesis. This study investigates the role of macrophage-derived, caspase-1 dependent interleukin-1beta (IL-1β) in an in vitro model of LVI.
Actions (Archive Staff Only)
|