Labour induction near term for women aged 35 or over: an economic evaluation

Walker, Kate F., Dritsaki, M., Bugg, George, Macpherson, Marion, McCormick, Carol, Grace, Nicky, Wildsmith, Chris, Bradshaw, Lucy, Smith, Gordon C.S. and Thornton, Jim (2017) Labour induction near term for women aged 35 or over: an economic evaluation. BJOG: An International Journal of Obstetrics & Gynaecology, 124 (6). pp. 929-934. ISSN 1471-0528

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Abstract

Objective Induction of labour at 39 weeks for nulliparous women aged 35 years and over may prevent stillbirths and does not increase caesarean births, so it may be popular. But the overall costs and benefits of such a policy have not been compared.

Design A cost–utility analysis alongside a randomised controlled trial (the 35/39 trial).

Setting Obstetric departments of 38 UK National Health Service hospitals and one UK primary-care trust.

Population Nulliparous women aged 35 years or over on their expected due date, with a singleton live fetus in a cephalic presentation.

Methods Costs were estimated from the National Health Service and Personal Social Services perspective and quality-adjusted life-years (QALYs) were calculated based on patient responses to the EQ-5D at baseline and 4 weeks.

Main outcome measures Data on antenatal care, mode of delivery, analgesia in labour, method of induction, EQ-5D (baseline and 4 weeks postnatal) and participant-administered postnatal health resource use data were collected.

Results The intervention was associated with a mean cost saving of £263 and a small additional gain in QALYs (though this was not statistically significant), even without considering any possible QALY gains from stillbirth prevention.

Conclusion A policy of induction of labour at 39 weeks for women of advanced maternal age would save money.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/857191
Additional Information: This is the peer reviewed version of the following article: K.F.Walker, M.Dritsaki, G.Bugg, M.Macpherson , C.McCormick, N.Grace, C.Wildsmith, L.Bradshaw, G.C.S.Smith, J.G. Thornton. Labour induction near term for women aged 35 or over: an economic evaluation, BJOG, v. 124, issue 6, 2017, p. 929-934, which has been published in final form at doi:10.1111/1471-0528.14557. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Keywords: Cost-effectiveness; cost–utility; expectant management; induction of labour; nulliparous; advanced maternal age
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Child Health, Obstetrics and Gynaecology
University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Units > Clinical Trials Unit
Identification Number: https://doi.org/10.1111/1471-0528.14557
Depositing User: Eprints, Support
Date Deposited: 11 May 2017 10:28
Last Modified: 04 May 2020 18:42
URI: https://eprints.nottingham.ac.uk/id/eprint/42757

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