Do statin users adhere to a healthy diet and lifestyle?: the Australian Diabetes, Obesity and Lifestyle Study

Johal, Simran, Jamsen, Kris M., Bell, Simon J., McNamara, Kevin P., Magliano, Dianna, Liew, Danny, Ryan-Atwood, Taliesin E., Anderson, Claire and Ilomäki, Jenni (2016) Do statin users adhere to a healthy diet and lifestyle?: the Australian Diabetes, Obesity and Lifestyle Study. European Journal of Preventive Cardiology . ISSN 2047-4881

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Lifestyle and dietary advice typically precedes or accompanies the prescription of statin medications. However, evidence for adherence to this advice is sparse. The objective was to compare saturated fat intake, exercise, alcohol consumption and smoking between statin users and non-users in Australia.


Data were analysed for 4614 participants aged ≥37 years in the Australian Diabetes, Obesity and Lifestyle study in 2011–2012. Statin use, smoking status and physical activity were self-reported. Saturated fat and alcohol intake were measured via a food frequency questionnaire. Multinomial logistic regression was used to compute adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between statin use and the four lifestyle factors. All models were adjusted for age, sex, education, number of general practitioner visits, body mass index, hypertension, diabetes and prior cardiovascular diseases.


In total 1108 (24%) participants used a statin. Statin users were 29% less likely to be within the highest quartile versus the lowest quartile of daily saturated fat intake compared to non-users (OR 0.71, 95% CI 0.54–0.94). There were no statistically significant associations between statin use and smoking, physical activity or alcohol consumption.


Smoking status, alcohol consumption and exercise level did not differ between users and non-users of statins. However, statin users were less likely to consume high levels of saturated fat than non-users. We found no evidence that people took statins to compensate for a poor diet or lifestyle.

Item Type: Article
Additional Information: Copyright The European Society of Cardiology 2016
Keywords: Smoking, Alcohol drinking, Exercise, Diet, HMG-CoA reductase inhibitors, Epidemiology, Cohort study
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Pharmacy
Identification Number:
Depositing User: Eprints, Support
Date Deposited: 01 Mar 2017 11:48
Last Modified: 04 May 2020 18:25

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