Anti-confocal assessment of middle ear inflammation

Jung, David S., Crowe, John A., Birchall, John P., Somekh, Michael G. and See, Chung W. (2016) Anti-confocal assessment of middle ear inflammation. Biomedical Optics Express, 8 (1). pp. 230-242. ISSN 2156-7085

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To improve the diagnostic prediction of recurrence of otitis media with effusion after surgery, an anti-confocal system combined with spectroscopic measurements is proposed to reject unwanted signals from the eardrum and assess the blood content. The anti-confocal system was experimentally evaluated on both optical middle ear phantom and human skin. Results showed effective rejection of signals from the eardrum using a central stop replacing the confocal pinhole, while still detecting signals from the middle ear mucosa. The system is sensitive to changes in blood content, but scattering and absorption characteristics of the eardrum can distort the measurement. Confocal detection of eardrum properties was shown to be a promising approach to correct measurements.

Item Type: Article
Keywords: Confocal microscopy, Medical and biological imaging, Otolaryngology, Imaging through turbid media
Schools/Departments: University of Nottingham, UK > Faculty of Engineering > Department of Electrical and Electronic Engineering
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Depositing User: Eprints, Support
Date Deposited: 14 Feb 2017 11:39
Last Modified: 04 May 2020 18:26

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