Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata

Planchestainer, Matteo, Contente, Martina Letizia, Cassidy, Jennifer, Molinari, Francesco, Tamborini, Lucia and Paradisi, Francesca (2017) Continuous flow biocatalysis: production and in-line purification of amines by immobilised transaminase from Halomonas elongata. Green Chemistry, 19 . pp. 372-375. ISSN 1463-9262

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Abstract

The continuous flow synthesis of a series of amines was successfully achieved by exploiting the enhanced stability and broad substrate scope of an immobilised transaminases from Halomonas elongata (HEWT). A series of substrates were tested in flow reactors and transformed to the corresponding amines in good to excellent yields. The process was implemented with an integrated in-line purification step for the recovery of the pure amines.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/830908
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Chemistry
Identification Number: 10.1039/c6gc01780k
Depositing User: Bramwell, Roseanna
Date Deposited: 27 Jan 2017 11:34
Last Modified: 04 May 2020 18:23
URI: https://eprints.nottingham.ac.uk/id/eprint/40105

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