Novel gonadal characteristics in an aged bovine freemartin

Remnant, J.G., Lea, Richard G., Allen, Ceri E., Huxley, J.N., Robinson, Robert S. and Brower, A. (2014) Novel gonadal characteristics in an aged bovine freemartin. Animal Reproduction Science, 146 (1-2). pp. 1-4. ISSN 1873-2232

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The gonads from a five year old freemartin Holstein animal were subjected to morphological analysis and to immunohistochemistry using antibodies against developmental and functional markers. We demonstrate, for the first time, the retention of anti-mullerian hormone (AMH) producing intratubular cells (Sertoli cells) in the context of abundant steroidogenic interstitial cells, and structures consistent with clusters of luteal cells. This novel report describes the clinical, gross and histological findings accompanying this newly described gonadal immunophenotype, and its implication in the understanding of freemartin development.

Item Type: Article
Keywords: Anti-Mullerian Hormone (AMH), Bovine, CYP17A1, Freemartin, Gonad
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Veterinary Medicine and Science
Identification Number:
Depositing User: Remnant, John
Date Deposited: 30 Jun 2016 12:21
Last Modified: 04 May 2020 16:43

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