The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder

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Groom, Madeleine J., Young, Zoe, Hall, Charlotte L., Gillott, Alinda and Hollis, Chris (2016) The incremental validity of a computerised assessment added to clinical rating scales to differentiate adult ADHD from autism spectrum disorder. Psychiatry Research, 243 . pp. 168-173. ISSN 1872-7123

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Official URL: http://www.sciencedirect.com/science/article/pii/S0165178115307125

Abstract

There is a clinical need for objective evidence-based measures that are sensitive and specific to ADHD when compared with other neurodevelopmental disorders. This study evaluated the incremental validity of adding an objective measure of activity and computerised cognitive assessment to clinical rating scales to differentiate adult ADHD from Autism spectrum disorders (ASD).

Adults with ADHD (n=33) or ASD (n=25) performed the QbTest, comprising a Continuous Performance Test with motion-tracker to record physical activity. QbTest parameters measuring inattention, impulsivity and hyperactivity were combined to provide a summary score (‘QbTotal’). Binary stepwise logistic regression measured the probability of assignment to the ADHD or ASD group based on scores on the Conners Adult ADHD Rating Scale–subscale E (CAARS-E) and Autism Quotient (AQ10) in the first step and then QbTotal added in the second step. The model fit was significant at step 1 (CAARS-E, AQ10) with good group classification accuracy. These predictors were retained and QbTotal was added, resulting in a significant improvement in model fit and group classification accuracy. All predictors were significant. ROC curves indicated superior specificity of QbTotal. The findings present preliminary evidence that adding QbTest to clinical rating scales may improve the differentiation of ADHD and ASD in adults.

Item Type:	Article
RIS ID:	https://nottingham-repository.worktribe.com/output/808499
Keywords:	Continuous Performance Test; assessment; QbTest
Schools/Departments:	University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Psychiatry and Applied Psychology
Identification Number:	https://doi.org/10.1016/j.psychres.2016.06.042
Depositing User:	Hall, Charlotte
Date Deposited:	30 Jun 2016 07:46
Last Modified:	04 May 2020 18:08
URI:	https://eprints.nottingham.ac.uk/id/eprint/34513

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