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Hook, Andrew, Morgan, Alexander and Winkler, David A. (2015) Materiomics: a toolkit for developing new biomaterials. In: Tissue engineering. Second edition. Elsevier, Amsterdam. ISBN 9780124201453

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Abstract

Learning Objectives

• To understand the what materiomics is and why it is required

• To become familiar with the various approaches used to design materiomic experiments

• To learn what a polymer microarray is, what it is used for and how it is produced

• To appreciate the complexity of material-biological interactions

• To become familiar with computational modelling methods as applied to biomaterials

• To gain an insight into how materiomics has and will continue to benefit tissue engineering

Scope of the chapter

The materials that are employed in regenerative medicine often react unfavourably with in vivo (induce clotting, promote bacterial infection). There is a need to develop new materials that provide the required cell response, but how is this best achieved considering the huge number of polymeric materials that could be synthesised? This chapter is a description of how materials discovery should most effectively be carried out in the developing paradigm of materiomics. We define and describe the components of this approach and methodology with the aim of providing a starting point for new users to effectively ‘dock’ into the existing research.

Item Type:	Book Section
RIS ID:	https://nottingham-repository.worktribe.com/output/988457
Schools/Departments:	University of Nottingham, UK > Faculty of Science > School of Pharmacy
Depositing User:	Alexander, Morgan
Date Deposited:	20 Nov 2015 14:29
Last Modified:	04 May 2020 20:11
URI:	https://eprints.nottingham.ac.uk/id/eprint/30874

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