Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes

Stepek, Gillian, Curtis, R.H.C., Kerry, B.R., Shewry, P.R., Clark, S.J., Lowe, Ann, Duce, I.R., Buttle, David J. and Behnke, J.M. (2007) Nematicidal effects of cysteine proteinases against sedentary plant parasitic nematodes. Parasitology, 134 (12). pp. 1831-1838. ISSN 0031-1820

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Cysteine proteinases from the fruit and latex of plants, such as papaya, pineapple and fig, have previously been shown to have substantial anthelmintic efficacy, in vitro and in vivo, against a range of animal parasitic nematodes. In this paper, we describe the in vitro effects of these plant extracts against 2 sedentary plant parasitic nematodes of the genera Meloidogyne and Globodera. All the plant extracts examined caused digestion of the cuticle and decreased the activity of the tested nematodes. The specific inhibitor of cysteine proteinases, E-64, blocked this activity completely, indicating that it was essentially mediated by cysteine proteinases. In vitro, plant cysteine proteinases are active against second-stage juveniles of M. incognita and M. javanica, and some cysteine proteinases also affect the second-stage juveniles of Globodera rostochiensis. It is not known yet whether these plant extracts will interfere with, or prevent invasion of, host plants.

Item Type: Article
Additional Information: Copyright Cambridge University Press.
Keywords: plant parasitic nematodes, Meloidogyne spp., Globodera rostochiensis, plant cysteine proteinases, in vitro, nematicide
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Life Sciences
Identification Number:
Depositing User: Behnke, Professor Jerzy M.
Date Deposited: 27 Jul 2015 08:16
Last Modified: 04 May 2020 20:29

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