• Login
• Admin

Article

Jevnikar, Zala and Östling, Jörgen and Ax, Elisabeth and Calvén, Jenny and Thörn, Kristofer and Israelsson, Elisabeth and Öberg, Lisa and Singhania, Akul and Lau, Laurie C.K. and Wilson, Susan J. and Ward, Jonathan A. and Chauhan, Anoop and Sousa, Ana R. and De Meulder, Bertrand and Loza, Matthew J. and Baribaud, Frédéric and Sterk, Peter J. and Chung, Kian Fan and Sun, Kai and Guo, Yike and Adcock, Ian M. and Payne, Debbie and Dahlen, Barbro and Chanez, Pascal and Shaw, Dominick E. and Krug, Norbert and Hohlfeld, Jens M. and Sandström, Thomas and Djukanovic, Ratko and James, Anna and Hinks, Timothy S.C. and Howarth, Peter H. and Vaarala, Outi and van Geest, Marleen and Olsson, Henric K. (2018) Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation. Journal of Allergy and Clinical Immunology . ISSN 0091-6749

Hanratty, Catherine E. and Matthews, John G. and Arron, Joseph R. and Choy, David F. and Pavord, Ian D. and Bradding, P. and Brightling, Christopher E. and Chaudhuri, Rekha and Cowan, Douglas C. and Djukanovic, Ratko and Gallagher, Nicola and Fowler, Stephen J. and Hardman, Tim C. and Harrison, Tim and Holweg, Cécile T. and Howarth, Peter H. and Lordan, James and Mansur, Adel H. and Menzies-Gow, Andrew and Mosesova, Sofia and Niven, Robert M. and Robinson, Douglas S. and Shaw, Dominick E. and Walker, Samantha and Woodcock, Ashley and Heaney, Liam G. (2018) A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial. Trials, 19 . p. 5. ISSN 1745-6215

Housley, Gemma and Lewis, Sarah and Usman, Adeela and Gordon, Adam L. and Shaw, Dominick E. (2017) Accurate identification of hospital admissions from care homes; development and validation of an automated algorithm. Age and Ageing . ISSN 0002-0729

Hekking, Pieter-Paul and Loza, Matthew J. and Pavlidis, Stelios and De Meulder, Bertrand and Lefaudeux, Diane and Baribaud, Frederic and Auffray, Charles and Wagener, Ariane H. and Brinkman, Paul and Lutter, René and Bansal, Aruna T. and Sousa, Ana R. and Bates, Stewart A. and Pandis, Ioannis and Fleming, Louise J. and Shaw, Dominick E. and Fowler, Stephen J. and Guo, Yike and Meiser, Andrea and Sun, Kai and Corfield, Julie and Howarth, Peter and Bel, Elisabeth H. and Adcock, Ian M. and Chung, Kian Fan and Djukanovic, Ratko and Sterk, Peter J. (2017) Transcriptomic gene signatures associated with persistent airflow limitation in patients with severe asthma. European Respiratory Journal, 50 (3). p. 1602298. ISSN 1399-3003

Williams, Neil C. and Hunter, Kirsty A. and Shaw, Dominick E. and Jackson, Kim G. and Sharpe, Graham R. and Johnson, Michael A. (2017) Comparable reductions in hyperpnoea-induced bronchoconstriction and markers of airway inflammation after supplementation with 6·2 and 3·1 g/d of long-chain n-3 PUFA in adults with asthma. British Journal of Nutrition, 117 (10). pp. 1379-1389. ISSN 1475-2662

Pilcher, Janine and Patel, Mitesh and Pritchard, Alison and Thayabaran, Darmiga and Ebmeier, Stefan and Shaw, Dominick E. and Black, Peter and Braithwaite, Irene and Weatherall, Mark and Beasley, Richard (2017) Beta-agonist overuse and delay in obtaining medical review in high risk asthma: a secondary analysis of data from a randomised controlled trial. npj Primary Care Respiratory Medicine, 27 (1). p. 33. ISSN 2055-1010

Naveed, Shams-un-nisa and Clements, Debbie and Jackson, David J. and Philp, Christopher and Billington, Charlotte K. and Soomro, Irshad N. and Reynolds, Catherine and Harrison, Timothy W. and Johnston, Sebastian L. and Shaw, Dominick E. and Johnson, Simon R. (2017) MMP-1 activation contributes to airway smooth muscle growth and asthma severity. American Journal of Respiratory and Critical Care Medicine, 195 (8). pp. 1000-1009. ISSN 1535-4970

Howard, Sam and Lang, Alexandra. R. and Sharples, Sarah and Shaw, Dominick E. (2016) What are the pros and cons of electronically monitoring inhaler use in asthma?: a multistakeholder perspective. BMJ Open Respiratory Research, 3 (1). e000159/1-e000159/10. ISSN 2052-4439

Wilson, Susan J. and Ward, Jonathan A. and Sousa, Ana R. and Corfield, Julie and Bansal, Aruna T. and De Meulder, Bertrand and Lefaudeux, Diane and Auffray, Charles and Loza, Matthew J. and Baribaud, Frederic and Fitch, Neil and Sterk, Peter J. and Chung, Kian Fan and Gibeon, David and Sun, Kai and Guo, Yi-ke and Adcock, Ian M. and Djukanovic, Ratko and Dahlen, Barbro and Chanez, Pascal and Shaw, Dominick E. and Krug, Norbert and Hohlfeld, Jens and Sandström, Thomas and Howarth, Peter H. (2016) Severe asthma exists despite suppressed tissue inflammation: findings of the U-BIOPRED study. European Respiratory Journal, 48 (5). pp. 1307-1319. ISSN 1399-3003

Pérez López, Iker and Brown, Michael and Pinchin, James and Martindale, Sarah and Sharples, Sarah and Shaw, Dominick E. and Blakey, John (2016) Out of hours workload management: Bayesian inference for decision support in secondary care. Artificial Intelligence in Medicine . ISSN 1873-2860

Slater, Mariel and Torr, Elizabeth and Harrison, Timothy W. and Forrester, Doug L. and Knox, Alan and Shaw, Dominick E. and Sayers, Ian (2016) The differential effects of azithromycin on the airway epithelium in vitro and in vivo. Physiological Reports, 4 (18). e12960/1-e12960/15. ISSN 2051-817X

Slater, Mariel G. and Pavord, Ian D. and Shaw, Dominick E. (2016) Step 4: stick or twist? A review of asthma therapy. BMJ Open Respiratory Research, 3 (1). e000143/1-e000143/7. ISSN 2052-4439

Williams, Neil C. and Johnson, Michael A. and Shaw, Dominick E. and Spendlove, Ian and Vulevic, Jelena and Sharpe, Graham R. and Hunter, Kirsty A. (2016) A prebiotic galactooligosaccharide mixture reduces severity of hyperpnoea-induced bronchoconstriction and markers of airway inflammation. British Journal of Nutrition, 116 (05). pp. 798-804. ISSN 1475-2662

Khuo, Chih-Hsi Scott and Pavlidis, Stelios and Loza, Matthew and Baribaud, Fred and Rowe, Anthony and Pandis, Ioannis and Hoda, Uruj and Rossios, Christos and Sousa, Ana and Wilson, Susan J. and Howarth, Peter and Dahlen, Barbro and Dahlen, Sven-Erik and Chanez, Pascal and Shaw, Dominick E. and Krug, Norbert and Sandström, Thomas and De Meulder, Betrand and Lefaudeux, Diane and Fowler, Stephen and Fleming, Louise and Corfield, Julie and Auffray, Charles and Sterk, Peter J. and Djukanovic, Ratko and Guo, Yike and Adcock, Ian M. and Chung, Kian Fan (2016) A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED. American Journal of Respiratory and Critical Care Medicine . ISSN 1535-4970

Leroyer, Christophe and Anderson, J.R. and Mortimer, K. and Pang, L. and Smith, K.M. and Bailey, H. and Hodgson, D.B. and Shaw, Dominick E. and Knox, A.J. and Harrison, Timothy W. (2016) Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial. PLoS ONE, 11 (8). e0160257. ISSN 1932-6203

Anderson, J.R. and Mortimer, K. and Pang, Linhua and Smith, K.M. and Bailey, H. and Hodgson, D.B. and Shaw, Dominick E. and Knox, Alan J. and Harrison, Timothy W. (2016) Evaluation of the PPAR-γ agonist pioglitazone in mild asthma: a double-blind randomized controlled trial. PLoS ONE, 11 (8). e0160257/1-e0160257/15. ISSN 1932-6203

Torr, Elizabeth and Heath, Meg and Mee, Maureen and Shaw, Dominick E. and Sharp, Tyson V. and Sayers, Ian (2016) Expression of polycomb protein BMI-1 1 maintains the plasticity of basal 2 bronchial epithelial cells. Physiological Reports, 4 (16). e12847. ISSN 2051-817X

Martin, M.J. and Lee, H. and Meakin, G. and Green, A. and Simms, R.L. and Reynolds, C. and Winters, S. and Shaw, Dominick E. and Soomro, Irshad N. and Harrison, Timothy W. (2016) Assessment of a rapid liquid-based cytology method for measuring sputum cell counts. Thorax . ISSN 1468-3296

Zaccardi, Francesco and Davies, Melanie J. and Dhalwani, Nafeesa N. and Webb, David R. and Housley, Gemma and Shaw, Dominick E. and Hatton, James W. and Khunti, Kamlesh (2016) Trends in hospital admissions for hypoglycaemia in England: a retrospective, observational study. Lancet Diabetes & Endocrinology, 4 (8). pp. 677-685. ISSN 2213-8595

Howard, Sam and Lang, Alexandra. R. and Sharples, Sarah and Shaw, Dominick E. (2016) See I told you I was taking it! - attitudes of adolescents with asthma towards a device monitoring their inhaler use: Implications for future design. Applied Ergonomics . ISSN 0003-6870 (In Press)

Malkar, Aditya and Wilson, Emma and Harrison, Timothy W. and Shaw, Dominick E. and Creaser, Colin (2016) Untargeted metabolic profiling of saliva by liquid chromatography-mass spectrometry for the identification of potential diagnostic biomarkers of asthma. Analytical Methods, 8 (27). pp. 5407-5413. ISSN 1759-9679

Brown, Michael and Pinchin, James and Valand, Reena and Larkin, Christopher and Pattinson, Joanne and Benning, Kelly and Housley, Gemma and Hatton, Jim and Shaw, Dominick E. and Syrysko, Paul and Sharples, Sarah and Blakey, John (2016) NightShift simulation to train newly qualified doctors in non-technical skills: a feasibility study. Future Hospital Journal, 3 (2). pp. 94-98. ISSN 2055-3331

Ketelaar, M.E. and Nawijn, Martijn C. and Shaw, Dominick E. and Koppelman, Gerard H. and Sayers, Ian (2016) The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma. Clinical & Experimental Allergy, 46 (6). pp. 884-887. ISSN 1365-2222

Hodgson, David and Anderson, John and Reynolds, Catherine and Oborne, Janet and Meakin, Garry and Bailey, Helen and Shaw, Dominick E. and Mortimer, Kevin and Harrison, Tim (2016) The effects of azithromycin in treatment-resistant cough: a randomized, double-blind, placebo-controlled trial. Chest, 149 (4). pp. 1052-1060. ISSN 1931-3543

McKeever, Tricia M. and Hearson, Glenn and Housley, Gemma and Reynolds, Catherine and Kinnear, William and Harrison, Timothy W. and Kelly, Anne-Maree and Shaw, Dominick E. (2016) Using venous blood gas analysis in the assessment of COPD exacerbations: a prospective cohort study. Thorax, 71 (3). pp. 210-215. ISSN 1468-3296

Pilcher, Janine and Patel, Mitesh and Reddel, Helen K. and Pritchard, Alison and Black, Peter and Shaw, Dominick E. and Holt, Shaun and Weatherall, Mark and Beasley, Richard (2016) Effect of smoking status on the efficacy of the SMART regimen in high risk asthma. Respirology, 21 (5). pp. 858-866. ISSN 1440-1843

Shaw, Dominick E. and Sousa, Ana R. and Fowler, Stephen J. and Fleming, Louise J. and Roberts, Graham and Corfield, Julie and Pandis, Ioannis and Bansal, Aruna T. and Bel, Elisabeth H. and Auffray, Charles and Compton, Chris H. and Bisgaard, Hans and Bucchioni, Enrica and Caruso, Massimo and Chanez, Pascal and Dahlen, Barbro and Dahlen, Sven-Erik and Dyson, Kerry and Frey, Urs and Geiser, Thomas and Gerhardsson de Verdier, Maria and Gibeon, David and Guo, Yi-ke and Hashimoto, Simone and Hedlin, Gunilla and Jeyasingham, Elizabeth and Hekking, Pieter-Paul W. and Higenbottam, Tim and Horváth, Ildikó and Knox, Alan J. and Krug, Norbert and Erpenbeck, Veit J. and Larsson, Lars X. and Lazarinis, Nikos and Matthews, John G. and Middelveld, Roelinde and Montuschi, Paolo and Musial, Jacek and Myles, David and Pahus, Laurie and Sandström, Thomas and Seibold, Wolfgang and Singer, Florian and Strandberg, Karin and Vestbo, Jorgen and Vissing, Nadja and von Garnier, Christophe and Adcock, Ian M. and Wagers, Scott and Rowe, Anthony and Howarth, Peter and Wagener, Ariane H. and Djukanovic, Ratko and Sterk, Peter J. and Chung, Kian Fan (2015) Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort. European Respiratory Journal, 46 (5). pp. 1308-1321. ISSN 1399-3003

Fleming, Louise and Murray, Clare and Bansal, Aruna T. and Hashimoto, Simone and Bisgaard, Hans and Bush, Andrew and Frey, Urs and Hedlin, Gunilla and Singer, Florian and Aalderen, Wim M. van and Vissing, Nadja H. and Zolkipli, Zaraquiza and Selby, Anna and Fowler, Stephen and Shaw, Dominick E. and Chung, Kian Fan and Sousa, Ana R. and Wagers, Scott and Corfield, Julie and Pandis, Ioannis and Rowe, Anthony and Formaggio, Elena and Sterk, Peter J. and Roberts, Graham (2015) The burden of severe asthma in childhood and adolescence: results from the paediatric U-BIOPRED cohorts. European Respiratory Journal, 46 (5). pp. 1322-1333. ISSN 1399-3003

Lilburn, David M.L. and Tatler, Amanda L. and Six, Joseph S. and Lesbats, Clémentine and Habgood, Antony and Porte, Joanne and Hughes-Riley, Theodore and Shaw, Dominick E. and Jenkins, Gisli and Meersmann, Thomas (2015) Investigating lung responses with functional hyperpolarized xenon-129 MRI in an ex vivo rat model of asthma. Magnetic Resonance in Medicine . ISSN 1522-2594

Howard, Glen and Walker, Alex J. and Shaw, Dominick E. and Hatton, James W. (2015) Building analytic skills to drive improvements in patient care and organisational decision making: an information analysts’ development programme. Clinical Governance: an International Journal, 20 (3). pp. 134-145. ISSN 1758-6038

Lilburn, David M.L. and Lesbats, Clémentine and Six, Joseph S. and Dubuis, Eric and Yew-Booth, Liang and Shaw, Dominick E. and Belvisi, Maria G. and Birrell, Mark A. and Pavlovskaya, Galina E. and Meersmann, Thomas (2015) Hyperpolarized 83Kr magnetic resonance imaging of alveolar degradation in a rat model of emphysema. Journal of the Royal Society Interface, 12 (107). 20150192/1-20150192/12. ISSN 1742-5689

Patel, Mitesh Dilipkumar Kantilal and Shaw, Dominick E. (2015) A review of standard pharmacological therapy for adult asthma - Steps 1 to 5. Chronic Respiratory Disease, 12 (2). pp. 165-176. ISSN 1479-9723

Hodgson, David and Anderson, John and Reynolds, Catherine and Meakin, Garry and Bailey, Helen and Pavord, Ian and Shaw, Dominick E. and Harrison, Timothy W. (2015) A randomised controlled trial of small particle inhaled steroids in refractory eosinophilic asthma (SPIRA). Thorax, 70 (6). pp. 559-565. ISSN 1468-3296

Brown, Michael and Shaw, Dominick E. and Sharples, Sarah and Le Jeune, Ivan and Blakey, John (2015) A survey-based cross-sectional study of doctors’ expectations and experiences of non-technical skills for out of hours work. BMJ Open, 5 (2). e006102/1-e006102/6. ISSN 2044-6055

Patel, Mitesh and Pilcher, Janine and Hancox, Robert J. and Sheahan, Davitt and Pritchard, Alison and Braithwaite, Irene and Shaw, Dominick E. and Black, Peter and Weatherall, Mark and Beasley, Richard (2015) The use of β2-agonist therapy before hospital attendance for severe asthma exacerbations: a post-hoc analysis. npj Primary Care Respiratory Medicine, 25 . 14099/1-14099/9. ISSN 2055-1010

Wilson, Emma and McKeever, Tricia M. and Hargadon, Beverley and Hearson, Glenn and Anderson, John and Hodgson, David and Bailey, Helen and Meakin, Garry and Thomas, Mike and Pavord, Ian D. and Harrison, Timothy W. and Shaw, Dominick E. (2014) Exhaled nitric oxide and inhaled corticosteroid dose reduction in asthma: a cohort study. European Respiratory Journal, 44 (6). pp. 1705-1707. ISSN 1399-3003

Patel, Mitesh and Pilcher, Janine and Reddel, Helen K. and Qi, Victoria and Mackey, Bill and Tranquilino, Tyronne and Shaw, Dominick E. and Black, Peter (2014) Predictors of severe exacerbations, poor asthma control, and β-agonist overuse for patients with asthma. Journal of Allergy and Clinical Immunology: In Practice, 2 (6). 751-758.e1. ISSN 2213-2201

Slater, Mariel and Rivett, Damian W. and Williams, Lisa and Martin, Matthew and Harrison, Timothy W. and Sayers, Ian and Bruce, Kenneth D. and Shaw, Dominick E. (2014) The impact of azithromycin therapy on the airway microbiota in asthma. Thorax, 69 (7). pp. 673-674. ISSN 1468-3296

Wilson, Emma Elizabeth and McKeever, Tricia M. and Lobb, Claire and Sherriff, Tom and Gupta, Luke and Hearson, Glenn and Martin, Neil and Lindley, Martin R. and Shaw, Dominick E. (2014) Respiratory muscle specific warm-up and elite swimming performance. British Journal of Sports Medicine, 48 (9). pp. 789-791. ISSN 1473-0480

Rogers, Natasha K. and Clements, Debbie and Dongre, Arundhati and Harrison, Timothy W. and Shaw, Dominick E. and Johnson, Simon R. (2014) Extra-cellular matrix proteins induce matrix metalloproteinase-1 (MMP-1) activity and increase airway smooth muscle contraction in asthma. PLoS ONE, 9 (2). e90565/1-e90565/12. ISSN 1932-6203

Six, Joseph S. and Hughes-Riley, Theodore and Lilburn, David M.L. and Dorkes, Alan C. and Stupic, Karl F. and Shaw, Dominick E. and Morris, Peter G. and Hall, Ian P. and Pavlovskaya, Galina E. and Meersmann, Thomas (2014) Pulmonary MRI contrast using Surface Quadrupolar Relaxation (SQUARE) of hyperpolarized 83Kr. Magnetic Resonance Imaging, 32 (1). pp. 48-53. ISSN 1873-5894

Howard, Sam and Lang, Alexandra and Patel, Mitesh Dilipkumar Kantilal and Sharples, Sarah and Shaw, Dominick E. (2014) Electronic monitoring of adherence to inhaled medication in asthma. Current Respiratory Medicine Reviews, 10 (1). pp. 50-63. ISSN 1875-6387

Hughes-Riley, Theodore and Six, Joseph S. and Lilburn, D.M.L. and Stupic, Karl F. and Dorkes, Alan C. and Shaw, Dominick E. and Pavlovskaya, Galina E. and Meersmann, Thomas (2013) Cryogenics free production of hyperpolarized 129Xe and 83Kr for biomedical MRI applications. Journal of Magnetic Resonance, 237 . pp. 23-33. ISSN 1096-0856

McKeever, Tricia M. and Harrison, Timothy W. and Hubbard, Richard and Shaw, Dominick E. (2013) Inhaled corticosteroids and the risk of pneumonia in people with asthma. Chest, 144 (6). pp. 1788-1794. ISSN 1931-3543

Lilburn, David M.L. and Hughes-Riley, Theodore and Six, Joseph S. and Stupic, Karl F. and Shaw, Dominick E. and Pavlovskaya, Galina E. and Meersmann, Thomas (2013) Validating excised rodent lungs for functional hyperpolarized xenon-129 MRI. PLoS ONE, 8 (8). e73468/1-e73468/13. ISSN 1932-6203

Blakey, John and Fearn, Andrew and Shaw, Dominick E. (2013) What drives the 'August effect'?: an observational study of the effect of junior doctor changeover on out of hours work. JRSM Short Reports, 4 (8). ISSN 2042-5333

Sturney, Sharon C. and Storer, M.K. and Shaw, Dominick E. and Epton, M.J. (2013) Off-line breath acetone analysis in critical illness. Journal of Breath Research, 7 (3). pp. 1-9. ISSN 1752-7163

Conference or Workshop Item

Hughes, Nancy and Pinchin, James and Brown, Michael and Shaw, Dominick E. (2015) Navigating in large hospitals. In: 6th International Conference on Indoor Positioning and Indoor Navigation, 13-16 Oct 2015, Alberta, Canada.