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Blair, Gordon W. and Appleton, Jason P. and Law, Zhe Kang and Doubal, Fergus and Flaherty, Katie and Dooley, Richard and Shuler, Kirsten and Richardson, Carla and Hamilton, Iona and Shi, Yulu and Stringer, Michael and Boyd, Julia and Thrippleton, Michael J. and Sprigg, Nikola and Bath, Philip M.W. and Wardlaw, Joanna M. (2018) Preventing cognitive decline and dementia from cerebral small vessel disease: The LACI-1 Trial. Protocol and statistical analysis plan of a phase IIa dose escalation trial testing tolerability, safety and effect on intermediary endpoints of isosorbide mononitrate and cilostazol, separately and in combination. International Journal of Stroke, 13 (5). pp. 530-538. ISSN 1747-4949

Ovesen, Christian and Jakobsen, Janus Christian and Gluud, Christian and Steiner, Thorsten and Law, Zhe and Flaherty, Katie and Dineen, Robert and Bath, Philip M.W. and Sprigg, Nikola and Christensen, Hanne (2018) Prevention of haematoma progression by tranexamic acid in intracerebral haemorrhage patients with and without spot sign on admission scan: a statistical analysis plan of a pre-specified sub-study of the TICH-2 trial. BMC Research Notes, 11 . 379/1-379/8. ISSN 1756-0500

Sprigg, Nikola and Flaherty, Katie and Appleton, Jason P. and Al-Shahi Salman, Rustam and Bereczki, Daniel and Beridze, M. and Christensen, Hanne and Ciccone, Alfonso and Collins, Ronan and Czlonkowska, Anna and Dineen, Robert A. and Duley, Lelia and Egea-Guerrero, Juan Jose and England, Timothy J. and Krishnan, Kailash and Laska, Ann Charlotte and Law, Zhe Kang and Ozturk, Serefnur and Pocock, Stuart J. and Roberts, Ian and Robinson, Thompson G. and Roffe, Christine and Seiffge, David and Scutt, Polly and Thanabalan, Jegan and Werring, David and Whynes, David and Bath, Philip M. (2018) Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. The Lancet . ISSN 1474-547X

Bath, Philip M.W. and Woodhouse, Lisa J. and Appleton, Jason P. and Beridze, M. and Christensen, Hanne and Dineen, Robert A. and Duley, Lelia and England, Timothy J. and Flaherty, Katie and Havard, Diane and Heptinstall, Stan and James, Marilyn and Krishnan, Kailash and Markus, H.S. and Montgomery, Alan A. and Pocock, Stuart J. and Randall, Marc and Ranta, A. and Robinson, Thompson G. and Scutt, Polly and Venables, Graham S. and Sprigg, Nikola (2018) Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial. Lancet, 391 (10123). pp. 850-859. ISSN 1474-547X

Ker, Katherine and Prieto-Merino, David and Sprigg, Nikola and Mahmood, Abda and Bath, Philip M.W. and Kang Law, Zhe and Flaherty, Katie and Roberts, Ian (2018) The effectiveness and safety of antifibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis. Wellcome Open Research, 2 (120). pp. 1-10. ISSN 2398-502X

Dineen, Robert A. and Pszczolkowski, Stefan and Flaherty, Katie and Law, Zhe Kang and Morgan, Paul S. and Roberts, Ian and Werring, David and Al-Shahi Salman, Rustam and England, Timothy J. and Bath, Philip M.W. and Sprigg, Nikola (2018) Does tranexamic acid lead to changes in MRI-measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? An MRI sub-study nested within the double-blind randomised controlled TICH-2 trial. BMJ Open, 8 (2). e019930/1-e019930/7. ISSN 2044-6055

Flaherty, Katie and Bath, Philip M.W. and Dineen, Robert and Law, Zhe and Scutt, Polly and Pocock, Stuart and Sprigg, Nikola (2017) Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage’ (TICH-2) trial. Trials, 18 (1). 607/1-607/3. ISSN 1745-6215

Bath, Philip M.W. and Appleton, Jason P. and Beridze, M. and Christensen, Hanne and Dineen, Robert A. and Duley, Lelia and England, Timothy J. and Heptinstall, Stan and James, Marilyn and Krishnan, Kailash and Markus, H.S. and Pocock, Stuart J. and Ranta, A. and Robinson, Thompson G. and Flaherty, Katie and Scutt, Polly and Venables, G. and Woodhouse, Lisa J. and Sprigg, Nikola (2017) Baseline characteristics of the 3,096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischaemic Stroke' (TARDIS) trial. International Journal of Stroke, 12 (5). pp. 524-538. ISSN 1747-4949

Bath, Philip M.W. and May, Jane and Flaherty, Katie and Woodhouse, Lisa J. and Dovlatova, Natalia and Fox, Sue C. and England, Timothy J. and Krishnan, Kailash and Robinson, Thompson G. and Sprigg, Nikola and Heptinstall, Stan (2017) Remote assessment of platelet function in patients with acute stroke or transient ischaemic attack. Stroke Research and Treatment, 2017 . 7365684/1- 7365684/13. ISSN 2042-0056

Conference or Workshop Item

Woodhouse, Lisa J. and Flaherty, Katie and Appleton, Jason P. and Sprigg, Nikola and Bath, Philip M.W. (2018) Characteristics and outcomes of patients with or without a bleeding event: results from the triple antiplatelets for reducing dependency in ischaemic stroke (TARDIS) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Woodhouse, Lisa J. and Appleton, Jason P. and Flaherty, Katie and Dineen, Robert A. and Sprigg, Nikola and Bath, Philip M. (2018) Impact of atrial fibrillation diagnosis or carotid enderterectomy requirement on outcome in patients from the triple antiplatelets for reducing dependency after ischaemic stroke (TARDIS) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Appleton, Jason P. and Blair, Gordon W. and Flaherty, Katie and Law, Zhe Kang and Doubal, Fergus and Sprigg, Nikola and Bath, Philip M.W. and Wardlaw, Joanna M. (2018) Peripheral and central haemodynamics in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Appleton, Jason P. and Flaherty, Katie and Blair, Gordon W. and Law, Zhe Kang and Doubal, Fergus and Sprigg, Nikola and Bath, Philip M. and Wardlaw, Joanna M. (2018) Platelet and haemoglobin levels in patients on isosorbide mononitrate and/or cilostazol with lacunar ischaemic stroke: data from the LACI-1 trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Woodhouse, Lisa J. and Flaherty, Katie and Appleton, Jason P. and Sprigg, Nikola and Bath, Philip M.W. (2018) Prediction of major bleeding with a S2TOP-BLEED score in acute ischaemic stroke or TIA patients: a sub-study of the TARDIS trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Sprigg, Nikola and Flaherty, Katie and Law, Zhe Kang and Appleton, Jason P. and Scutt, Polly and Krishnan, Kailash and Bath, Philip M. (2018) Results from the tranexamic acid for primary intracerebral haemorrhage-2 (TICH-2) trial. In: 4th European Stroke Organisation Conference ​(ESOC 2018), 16-18 May 2018, Gothenburg, Sweden.

Sprigg, Nikola and Bath, Philip M.W. and Appleton, J. and Law, Z. and Flaherty, Katie and Scutt, Polly and Hyman-Taylor, Pauline and Adrian, M. and Stringer, M. and Longmate, J. and Gray, R. and Gregory, H. and Lysons, C. and Ali, A. (2017) TICH-2 Trial – Tranexamic Acid for Intracerebral Haemorrhage 2. In: 12th UK Stroke Forum Conference (UKSF 2017), 28-30 Nov 2017, Liverpool, UK.