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Number of items: 7.

Mistry, Shailesh N. and Jörg, Manuela and Lim, Herman and Vinh, Natalie B. and Sexton, Patrick M. and Capuano, Ben and Christopoulos, Arthur and Lane, J. Robert and Scammells, Peter J. (2015) 4-Phenylpyridin-2-one derivatives: a novel class of positive allosteric modulator of the M1 muscarinic acetylcholine receptor. Journal of Medicinal Chemistry . ISSN 1520-4804

Mistry, Shailesh N. and Shonberg, Jeremy and Draper-Joyce, Christopher J. and Klein Herenbrink, Carmen and Michino, Mayako and Shi, Lei and Christopoulos, Arthur and Capuano, Ben and Scammells, Peter J. and Lane, J. Robert (2015) Discovery of a novel class of negative allosteric modulator of the dopamine D2 receptor through fragmentation of a bitopic ligand. Journal of Medicinal Chemistry, 58 (17). pp. 6819-6843. ISSN 0022-2623

Abdul-Ridha, Alaa and Lane, J. Robert and Mistry, Shailesh N. and Lopez, Laura and Sexton, Patrick M. and Scammells, Peter J. and Christopoulos, Arthur and Canals, Meritxell (2014) Mechanistic insights into allosteric structure-function relationships at the M1 muscarinic acetylcholine receptor. Journal of Biological Chemistry, 289 (48). pp. 33701-33711. ISSN 0021-9258

Abdul-Ridha, Alaa and López, Laura and Keov, Peter and Thal, David M. and Mistry, Shailesh N. and Sexton, Patrick M. and Lane, J. Robert and Canals, Meritxell and Christopoulos, Arthur (2014) Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor. Journal of Biological Chemistry, 289 (9). pp. 6067-6079. ISSN 0021-9258

Mistry, Shailesh N. and Lim, Herman and Jörg, Manuela and Capuano, Ben and Christopoulos, Arthur and Lane, J. Robert and Scammells, Peter J. (2016) Novel fused arylpyrimidinone based allosteric modulators of the M1 muscarinic acetylcholine receptor. ACS Chemical Neuroscience, 7 (5). pp. 647-661. ISSN 1948-7193

Shonberg, Jeremy and Draper-Joyce, Christopher and Mistry, Shailesh N. and Christopoulos, Arthur and Scammells, Peter J. and Lane, J. Robert and Capuano, Ben (2015) Structure–activity study of N-((trans)-4-(2-(7-cyano-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)cyclohexyl)-1H-indole-2-carboxamide (SB269652), a bitopic ligand that acts as a negative allosteric modulator of the dopamine D2 receptor. Journal of Medicinal Chemistry, 58 (13). pp. 5287-5307. ISSN 0022-2623

Mistry, Shailesh N. and Valant, Celine and Sexton, Patrick M. and Capuano, Ben and Christopoulos, Arthur and Scammells, Peter J. (2013) Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor. Journal of Medicinal Chemistry, 56 (12). pp. 5151-5172. ISSN 0022-2623

This list was generated on Mon Mar 27 06:00:33 2017 UTC.