Card, Timothy, Enck, Paul, Barbara, Giovanni, Boeckxstaens, Guy E.E, Santos, Javier, Azpiroz, Fernando, Mearin, Fermin, Aziz, Qasim, Marshall, John and Spiller, Robin C.
(2018)
Post infectious IBS: defining its clinical features and prognosis using an internet-based survey.
United European Gastroenterology Journal
.
ISSN 2050-6414
Abstract
Background: Gastrointestinal infection is an important risk factor for developing IBS. Our aim was to characterise postinfectious IBS (PI-IBS) compared to other IBS patients.
Methods: An internet survey of IBS patients using Rome III diagnostic questionnaire, Hospital Anxiety & Depression Scale (HADS) and Patient Health Questionnaire-12 somatic symptom score (PHQ12-SS) documenting the mode of onset.
Results: 7811 participants, 63.2% female of whom 1004 (13.3%) met criteria for PI-IBS. 70% of PI-IBS described sudden onset, 35% onset while travelling, 49.6% vomiting, 49.9 fever and 20.3% bloody diarrhoea. Compared to other IBS, PI-IBS was significantly associated with living in Northern Europe and North America, having a hysterectomy, not having an appendectomy, higher PHQ12-SS score and having more than one toilet in the family home. PI-IBS patients had more frequent stools. At 1 year recovery rate in PI-IBS and non-PI-IBS group was 19.7% and 22.2%, p=0.15. Recovery rates were lower for females (20.7%) versus males (38.8%), those with somatisation ( 23.0%) versus those without (33.2%) and living in North America or Northern Europe (21.1%) versus living elsewhere (33.9%) p=<0.001.
Conclusion: PI-IBS accounts for around 13% of all IBS in this internet sample, with some distinctive features but a similar prognosis to the remainder.
| Item Type: |
Article
|
| Additional Information: |
Reprinted by permission of SAGE Publications. |
| Keywords: |
Infection, Irritable bowel syndrome, Survey, Multinational, Diarrhoea |
| Schools/Departments: |
University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Epidemiology and Public Health
University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Nottingham Digestive Diseases Centre |
| Identification Number: |
https://doi.org/10.1177/2050640618779923 |
| Depositing User: |
Claringburn, Tara
|
| Date Deposited: |
11 May 2018 07:45 |
| Last Modified: |
05 Jun 2018 10:14 |
| URI: |
https://eprints.nottingham.ac.uk/id/eprint/51696 |
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