Waiting time distributions for clusters of complex molecules

Thul, Ruediger and Falcke, Martin Waiting time distributions for clusters of complex molecules. Europhysics Letters .

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Abstract

Waiting time distributions are in the core of theories

for a large variety of subjects ranging from the analysis of patch clamp

records to stochastic excitable systems. Here, we present a novel

exact method for the calculation of waiting time distributions for

state transitions of complex molecules with independent subunit

dynamics.The absorbing state is a specific set of subunit states, i.e. is defined on the molecule level. Consequently, we formulate the problem as a random walk in the molecule state space. The subunits can posses an

arbitrary number of states and any topology of transitions between

them. The method circumvents problems arising from combinatorial

explosion due to subunit coupling and requires solutions of the

subunit master equation only.

Item Type: Article
Schools/Departments: University of Nottingham UK Campus > Faculty of Science > School of Mathematical Sciences
Depositing User: Thul, Dr Ruediger
Date Deposited: 22 Oct 2007 15:56
Last Modified: 24 Jun 2011 14:31
URI: http://eprints.nottingham.ac.uk/id/eprint/680

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