Public-health-driven microfluidic technologies: from separation to detection

Zhang, Xiangzhi and Xu, Xiawei and Wang, Jing and Wang, Chengbo and Yan, Yuying and Wu, Aiguo and Ren, Yong (2021) Public-health-driven microfluidic technologies: from separation to detection. Micromachines, 12 (4). p. 391. ISSN 2072-666X

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Abstract

Separation and detection are ubiquitous in our daily life and they are two of the most important steps toward practical biomedical diagnostics and industrial applications. A deep understanding of working principles and examples of separation and detection enables a plethora of applications from blood test and air/water quality monitoring to food safety and biosecurity; none of which are irrelevant to public health. Microfluidics can separate and detect various particles/aerosols as well as cells/viruses in a cost-effective and easy-to-operate manner. There are a number of papers reviewing microfluidic separation and detection, but to the best of our knowledge, the two topics are normally reviewed separately. In fact, these two themes are closely related with each other from the perspectives of public health: understanding separation or sorting technique will lead to the development of new detection methods, thereby providing new paths to guide the separation routes. Therefore, the purpose of this review paper is two-fold: reporting the latest developments in the application of microfluidics for separation and outlining the emerging research in microfluidic detection. The dominating microfluidics-based passive separation methods and detection methods are discussed, along with the future perspectives and challenges being discussed. Our work inspires novel development of separation and detection methods for the benefits of public health.

Item Type: Article
Keywords: Detection; Lab-on-a-chip; Microfluidic system; Public health; Separation
Schools/Departments: University of Nottingham Ningbo China > Faculty of Science and Engineering > Department of Mechanical, Materials and Manufacturing Engineering
Identification Number: https://doi.org/10.3390/mi12040391
Depositing User: Yu, Tiffany
Date Deposited: 04 Jun 2021 07:30
Last Modified: 04 Jun 2021 07:30
URI: http://eprints.nottingham.ac.uk/id/eprint/65377

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