Protozoal and bacterial infections, including the gut microbiota, in wild rodents and the effects of environmental and host variables on their composition

Goertz, Sarah (2020) Protozoal and bacterial infections, including the gut microbiota, in wild rodents and the effects of environmental and host variables on their composition. PhD thesis, University of Nottingham.

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Abstract

Chapter 1 will detail the gut microbiota composition of wild house mice (Mus musculus domesticus) on the Isle of May and specifically focus on the spatial variability of the gut microbiota.

Chapter 2 will investigate the proximal colon and faecal microbiota composition of wild field voles (Microtus agrestis) from Kielder Forest. Differences between faecal and colon microbiota composition will be discussed as well as variability of the microbiota in individuals living in captivity for up to 24 hours compared to those in captivity for up to 48 hours.

Chapter 3 considers the importance of relatedness on colon microbiota variability in field voles. Individuals which are closely related, such as dams and their offspring, and their respective microbiota will be compared to one another as well as to the entire population to establish whether closely related individuals have a significantly more similar microbiota to one another than non-related individuals.

Finally, Chapter 4 will detail the haemoparasites present on the Isle of May and investigate whether environmental variables as well as presence of other parasites impacts on the presence or absence of haemoparasites. An association between haemoparasites and gut microbiota composition is also investigated.

Item Type: Thesis (University of Nottingham only) (PhD)
Supervisors: Bradley, Janette E.
MacColl, Andrew D.C.
Keywords: Microbiota, Immunology, Murine system, House mouse, Field vole, Parasites
Subjects: Q Science > QL Zoology
Faculties/Schools: UK Campuses > Faculty of Medicine and Health Sciences > School of Life Sciences
Item ID: 60846
Depositing User: Goertz, Sarah
Date Deposited: 14 Aug 2020 10:07
Last Modified: 14 Aug 2020 10:07
URI: http://eprints.nottingham.ac.uk/id/eprint/60846

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