Towards biologically active heterocycles from renewable aromatic starting materialsTools Anderson, Edward (2019) Towards biologically active heterocycles from renewable aromatic starting materials. PhD thesis, University of Nottingham.
AbstractThis thesis describes work undertaken over the past three years as part of the EPSRC Centre for Doctoral Training in Sustainable Chemistry. Our focus was on developing methods to generate the same important molecules in new, and better ways as judged by green & sustainability criteria. Overall, we have concentrated our efforts on the synthesis of heterocyclic molecules within the context of biologically active molecules. This has ranged from the synthesis of aromatic heterocycles in the form of naphthyridines, to the dearomatisation of aromatic molecules to generate spirocyclic, unsaturated amines.
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