Antimicrobials and antimicrobial resistance (AAMR)Tools Papangeli, Maria (2018) Antimicrobials and antimicrobial resistance (AAMR). MRes thesis, University of Nottingham.
AbstractAntibiotics resistance is an emerging threat for the health systems worldwide.700000 deaths annually are attributed to antibiotic resistant pathogens. The predictions for 2050 are devastating. By 2050, 10 million deaths that are linked to antibiotic resistance are expected. The antibiotic resistance along with the shortage of new antibiotics have created an antibiotic crisis. One solution to antimicrobial resistance could be the investment in new innovative methods against antimicrobial resistance. In the present study, two research projects with innovative strategies were undertaken. The first project examined the route of transmission of Enterococcus faecium in a suspected outbreak using WGS. The second project concerned the characterisation of chemosensory proteins in the pathogen Pseudomonas aeruginosa in order to elucidate the mechanism by which the bacterium senses anti-attachment surfaces
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