Sulfonimidates: useful synthetic intermediates for sulfoximine synthesis via C–S bond formation

Matos, Priscilla Mendonça and Lewis, William and Moore, Jonathan C. and Stockman, Robert A. (2018) Sulfonimidates: useful synthetic intermediates for sulfoximine synthesis via C–S bond formation. Organic Letters, 20 (12). pp. 3674-3677. ISSN 1523-7060

[img]
Preview
PDF - Requires a PDF viewer such as GSview, Xpdf or Adobe Acrobat Reader
Download (719kB) | Preview

Abstract

The ever-increasing prevalence of sulfoximine derivatives in drug discovery programmes has brought about a renaissance in the development of methods for their synthesis. Sulfoximine synthesis via C-S bond formation however has been comparatively underexplored. Herein, we report that sulfonimidates constitute a versatile precursor for the synthesis of medicinally relevant sulfoximines.

Item Type: Article
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Chemistry
Identification Number: https://doi.org/10.1021/acs.orglett.8b01473
Depositing User: Lashkova, Mrs Olga
Date Deposited: 14 Sep 2018 13:40
Last Modified: 07 Jun 2019 04:30
URI: http://eprints.nottingham.ac.uk/id/eprint/54976

Actions (Archive Staff Only)

Edit View Edit View