Sulfonimidates: useful synthetic intermediates for sulfoximine synthesis via C–S bond formationTools Matos, Priscilla Mendonça, Lewis, William, Moore, Jonathan C. and Stockman, Robert A. (2018) Sulfonimidates: useful synthetic intermediates for sulfoximine synthesis via C–S bond formation. Organic Letters, 20 (12). pp. 3674-3677. ISSN 1523-7060
Official URL: https://pubs.acs.org/doi/10.1021/acs.orglett.8b01473
AbstractThe ever-increasing prevalence of sulfoximine derivatives in drug discovery programmes has brought about a renaissance in the development of methods for their synthesis. Sulfoximine synthesis via C-S bond formation however has been comparatively underexplored. Herein, we report that sulfonimidates constitute a versatile precursor for the synthesis of medicinally relevant sulfoximines.
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