Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function

Tierney, Tim M. and Holmes, Niall and Meyer, Sofie S. and Boto, Elena and Roberts, Gillian and Leggett, James and Buck, Sarah and Duque-Muñoz, Leonardo and Litvak, Vladimir and Bestmann, Sven and Baldeweg, Torsten and Bowtell, Richard W. and Brookes, Matthew J. and Barnes, Gareth R. (2018) Cognitive neuroscience using wearable magnetometer arrays: non-invasive assessment of language function. NeuroImage . ISSN 1095-9572 (In Press)

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Abstract

Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically validated language lateralisation paradigm (covert verb generation: 120 trials, ~10 minutes total duration) in healthy adults (n=3). We show that it is possible to lateralise and localise language function on a case by case basis using this system. Specifically, we show that at a sensor and source level we can reliably detect a lateralising beta band (15-30Hz) desynchronization in all subjects. This is the first demonstration of studying human cognition with OPMs and not only highlights this technology’s utility as tool for (developmental) cognitive neuroscience but also its potential to contribute to surgical planning via mapping of eloquent cortex, especially in young children.

Item Type: Article
Keywords: Optically pumped magnetometers; Language; MEG
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Physics and Astronomy
Depositing User: Eprints, Support
Date Deposited: 19 Jul 2018 08:32
Last Modified: 19 Jul 2019 04:30
URI: http://eprints.nottingham.ac.uk/id/eprint/53029

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