Sotiropoulos, S.N., Moeller, S., Jbabdi, S., Xu, J., Andersson, J.L., Auerbach, E.J., Yacoub, E., Feinberg, D., Setsompop, K., Wald, L.L., Behrens, T.E.J., Ugurbil, K. and Lenglet, C.
(2013)
Effects of image reconstruction on fiber orientation mapping from multichannel diffusion MRI: reducing the noise floor using SENSE.
Magnetic Resonance in Medicine, 70
(6).
pp. 1682-1689.
ISSN 1522-2594
Full text not available from this repository.
Abstract
Purpose: To examine the effects of the reconstruction algorithm of magnitude images from multi-channel diffusion MRI on fibre orientation estimation.
Theory and Methods: It is well established that the method used to combine signals from different coil elements in multi-channel MRI can have an impact on the properties of the reconstructed magnitude image. Utilising a root-sum-of-squares (RSoS) approach results in a magnitude signal that follows an effective non-central-distribution. As a result, the noise floor, the minimum measurable in the absence of any true signal, is elevated. This is particularly relevant for diffusion-weighted MRI, where the signal attenuation is of interest.
Results: In this study, we illustrate problems that such image reconstruction characteristics may cause in the estimation of fibre orientations, both for model-based and model-free approaches, when modern 32-channel coils are employed. We further propose an alternative image reconstruction method that is based on sensitivity encoding (SENSE) and preserves the Rician nature of the single-channel, magnitude MR signal. We show that for the same k-space data, RSoS can cause excessive overfitting and reduced precision in orientation estimation compared to the SENSE-based approach.
Conclusion: These results highlight the importance of choosing the appropriate image reconstruction method for tractography studies that use multi-channel receiver coils for diffusion MRI acquisition.
| Item Type: |
Article
|
| RIS ID: |
https://nottingham-repository.worktribe.com/output/719347 |
| Additional Information: |
This is the peer reviewed version of the following article, which has been published in final form at https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.24623. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
| Keywords: |
Sum of Squares; SENSE; Rician; Non-central-X; Magnitude Image; Tractography |
| Schools/Departments: |
University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine |
| Identification Number: |
10.1002/mrm.24623 |
| Depositing User: |
Eprints, Support
|
| Date Deposited: |
11 Jul 2018 10:06 |
| Last Modified: |
04 May 2020 16:39 |
| URI: |
https://eprints.nottingham.ac.uk/id/eprint/52875 |
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