Cu(ii) complexes of a tridentate N,N,O-donor Schiff base of pyridoxal: synthesis, X-ray structures, DNA-binding properties and catecholase activity

Mondal, Satyajit and Chakraborty, Moumita and Mondal, Antu and Pakhira, Bholanath and Blake, Alexander J. and Sinn, Ekkehard and Chattopadhyay, Shyamal Kumar (2018) Cu(ii) complexes of a tridentate N,N,O-donor Schiff base of pyridoxal: synthesis, X-ray structures, DNA-binding properties and catecholase activity. New Journal of Chemistry, 42 (12). pp. 9588-9597. ISSN 1369-9261

Full text not available from this repository.

Abstract

Two new Cu(II) complexes [Cu(L1)(N3)](1) and [Cu(L1)(NCS)]n(2), where HL1 ((E)-4-((2(dimethylamino)ethylimino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol) is a N,N,O-donor Schiff base ligand, have been synthesized. These complexes were characterized on the basis of spectroscopic, electrochemical, and other physicochemical properties. X-ray crystal structure determination reveals that in complex 1, Cu(II) is in a square planar geometry with the N,N,O-donor ligand and a terminally coordinated azide ion. In complex 2, however, Cu(II) assumes a square pyramidal geometry, and apart from the tridentate Schiff base ligand there is a thiocyanate ion, which acts in a μ1,3-bridging mode, connecting adjacent Cu(II) atoms in an axial-equatorial fashion forming an one dimensional chain. Cyclic voltammetry shows that complexes undergo Cu(II)/Cu(I) reductions at −0.40 to −0.55V followed by imine reduction at around −0.7V. Cu(I)/Cu(0) reduction is observed at approximately −0.9V. Complex 1 also shows appreciable catalytic activity for the aerial oxidation of 3,5 DTBCH2 to DTBQ (catecholase activity). Both the complexes also show strong binding affinity towards calf-thymus DNA.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/939883
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Chemistry
Identification Number: https://doi.org/10.1039/C8NJ00418H
Depositing User: Eprints, Support
Date Deposited: 05 Jul 2018 11:04
Last Modified: 04 May 2020 19:41
URI: http://eprints.nottingham.ac.uk/id/eprint/52789

Actions (Archive Staff Only)

Edit View Edit View