Handgrip strength cannot be assumed a proxy for overall muscle strength

Yeung, Suey S.Y. and Reijnierse, Esmee M. and Trappenburg, Marijke C. and Hogrel, Jean-Yves and McPhee, Jamie S. and Piasecki, Mathew and Sipila, Sarianna and Salpakoski, Anu and Butler-Browne, Gillian and Pääsuke, Mati and Gapeyeva, Helena and Narici, Marco V. and Meskers, Carel G.M. and Maier, Andrea B. (2018) Handgrip strength cannot be assumed a proxy for overall muscle strength. Journal of the American Medical Directors Association . ISSN 1538-9375

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Abstract

Objectives: Dynapenia, low muscle strength, is predictive for negative health outcomes and is usually expressed as handgrip strength (HGS). Whether HGS can be a proxy for overall muscle strength and whether this depends on age and health status is controversial. This study assessed the agreement between HGS and knee extension strength (KES) in populations differing in age and health status.

Design: Data were retrieved from 5 cohorts.

Setting and Participants: Community, geriatric outpatient clinics, and a hospital. Five cohorts (960 individuals, 49.8% male) encompassing healthy young and older individuals, geriatric outpatients, and older individuals post hip fracture were included.

Measures: HGS and KES were measured according to the protocol of each cohort. Pearson correlation was performed to analyze the association between HGS and KES, stratified by sex. HGS and KES were standardized into sex-specific z scores. The agreement between standardized HGS and standardized KES at population level and individual level were assessed by intraclass correlation coefficients (ICC) and Bland-Altman analysis.

Results: Pearson correlation coefficients were low in healthy young (male: 0.36 to 0.45, female: 0.45) and healthy older individuals (male: 0.35 to 0.37, female: 0.44), and moderate in geriatric outpatients (male and female: 0.54) and older individuals post hip fracture (male: 0.44, female: 0.57) (P<.05, except for male older individuals post hip fracture [P¼.07]). Intraclass correlation coefficient values were poor to moderate in all populations (ie, healthy young individuals [0.41, 0.45], healthy older individuals [0.37, 0.41, 0.44], geriatric outpatients [0.54], and older individuals post hip fracture [0.54]). Bland-Altman analysis showed that within the same population of age and health status, agreement between HGS and KES varied on individual level.

Item Type: Article
Keywords: Muscle strength; knee extension strength; aged; geriatric assessment
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine
Identification Number: https://doi.org/10.1016/j.jamda.2018.04.019
Depositing User: Eprints, Support
Date Deposited: 21 Jun 2018 12:43
Last Modified: 26 Jun 2018 12:33
URI: http://eprints.nottingham.ac.uk/id/eprint/52547

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