Lie symmetries of nonlinear parabolic-elliptic systems and their application to a tumour growth model

Cherniha, Roman and Davydovych, Vasyl and King, John R. (2018) Lie symmetries of nonlinear parabolic-elliptic systems and their application to a tumour growth model. Symmetry, 10 (5). 171/1-171/21. ISSN 2073-8994

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Abstract

A generalisation of the Lie symmetry method is applied to classify a coupled system of reaction-diffusion equations wherein the nonlinearities involve arbitrary functions in the limit case in which one equation of the pair is quasi-steady but the other is not. A complete Lie symmetry classification, including a number of the cases characterised as being unlikely to be identified purely by intuition, is obtained. Notably, in addition to the symmetry analysis of the PDEs themselves, the approach is extended to allow the derivation of exact solutions to specific moving-boundary problems motivated by biological applications (tumour growth). Graphical representations of the solutions are provided and a biological interpretation is briefly addressed. The results are generalised on multi-dimensional case under the assumption of the radially symmetrical shape of the tumour.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/933045
Keywords: Lie symmetry classification; Exact solution; Nonlinear reaction-diffusion system; Tumour growth model; Moving-boundary problem
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Mathematical Sciences
Identification Number: https://doi.org/10.3390/sym10050171
Depositing User: Eprints, Support
Date Deposited: 04 Jun 2018 08:33
Last Modified: 04 May 2020 19:36
URI: http://eprints.nottingham.ac.uk/id/eprint/52221

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