Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake

Halford, Jason C.G. and Masic, Una and Marseaux, Cyril F.M. and Jones, Andrew J. and Lluch, Anne and Marciani, Luca and Mars, Monica and Vinoy, Sophie and Westerterp-Plantenga, Margriet and Mela, David J. (2018) Systematic review of the evidence for sustained efficacy of dietary interventions for reducing appetite or energy intake. Obesity Reviews . ISSN 1467-789X

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Abstract

We assessed evidence for changes in efficacy of food-based interventions aimed at reducing appetite or energy intake (EI), and whether this could be used to provide guidance on trial design.

A systematic search identified randomized controlled trials testing sustained efficacy of diets, foods, supplements or food ingredients on appetite and/or EI. Trials had to include sufficient exposure duration (≥3 days) with appetite and/or EI measured after both acute and repeated exposures.

Twenty-six trials met the inclusion criteria and reported data allowing for assessment of the acute and chronic effects of interventions. Most (21/26) measured appetite outcomes and over half (14/26) had objective measures of EI. A significant acute effect of the intervention was retained in 10 of 12 trials for appetite outcomes, and six of nine studies for EI. Initial effects were most likely retained where these were more robust and studies adequately powered. Where the initial, acute effect was not statistically significant, a significant effect was later observed in only two of nine studies for appetite and none of five studies for EI.

Maintenance of intervention effects on appetite or EI needs to be confirmed, but seem likely where acute effects are robust and replicable in adequately powered studies.

Item Type: Article
RIS ID: https://nottingham-repository.worktribe.com/output/941608
Keywords: Study duration, Satiety, Energy intake, Appetite
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Nottingham Digestive Diseases Centre
Identification Number: https://doi.org/10.1111/obr.12712
Depositing User: Marciani, Dr Luca
Date Deposited: 21 May 2018 09:07
Last Modified: 04 May 2020 19:42
URI: http://eprints.nottingham.ac.uk/id/eprint/51889

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