Nucleoside based self-assembling drugs for localized drug delivery

Skilling, Kathryn J., Stocks, Michael J., Kellam, Barrie, Ashford, Marianne, Bradshaw, Tracey, Burroughs, Laurence and Marlow, Maria (2018) Nucleoside based self-assembling drugs for localized drug delivery. ChemMedChem . ISSN 1860-7179

Full text not available from this repository.


We have synthesized a range of gelators based on nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and TEM. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the potential of nucleoside based gelators for localized drug delivery.

Item Type: Article
Additional Information: This is the peer-reviewed version of the following article, which has been published in final form at This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Keywords: drug delivery ; gels ; gemcitabine ; lamivudine ; nucleosides
Schools/Departments: University of Nottingham, UK > Faculty of Science > School of Pharmacy
Identification Number:
Depositing User: Eprints, Support
Date Deposited: 03 May 2018 08:54
Last Modified: 04 May 2020 19:35

Actions (Archive Staff Only)

Edit View Edit View