An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging

Andersson, Jesper L.R. and Sotiropoulos, Stamatios N. (2016) An integrated approach to correction for off-resonance effects and subject movement in diffusion MR imaging. NeuroImage, 125 . pp. 1063-1078. ISSN 1053-8119

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In this paper we describe a method for retrospective estimation and correction of eddy current (EC)-induced distortions and subject movement in diffusion imaging. In addition a susceptibility-induced field can be supplied and will be incorporated into the calculations in a way that accurately reflects that the two fields (susceptibility- and EC-induced) behave differently in the presence of subject movement. The method is based on registering the individual volumes to a model free prediction of what each volume should look like, thereby enabling its use on high b-value data where the contrast is vastly different in different volumes. In addition we show that the linear EC-model commonly used is insufficient for the data used in the present paper (high spatial and angular resolution data acquired with Stejskal–Tanner gradients on a 3 T Siemens Verio, a 3 T Siemens Connectome Skyra or a 7 T Siemens Magnetome scanner) and that a higher order model performs significantly better.

The method is already in extensive practical use and is used by four major projects (the WU-UMinn HCP, the MGH HCP, the UK Biobank and the Whitehall studies) to correct for distortions and subject movement.

Item Type: Article
Keywords: Diffusion; Eddy current; Movement; Susceptibility; Registration
Schools/Departments: University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine
Identification Number: 10.1016/j.neuroimage.2015.10.019
Depositing User: Eprints, Support
Date Deposited: 05 Apr 2018 08:27
Last Modified: 05 Apr 2018 13:37

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