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Rowlands, Martin, Walt, Gerrie van de, Bradley, Jim, Mannings, Alexa, Armstrong, Sarah, Bedforth, Nigel M., Moppett, Iain K. and Sahota, Opinder (2018) Femoral Nerve Block Intervention in Neck of Femur Fracture (FINOF): a randomized controlled trial. BMJ Open, 8 (4). e019650/1-e019650/8. ISSN 2044-6055

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Abstract

Objective

Fractured neck of femur is a severely painful condition with significant mortality and morbidity. We investigated whether early and continuous use of femoral nerve block can improve pain on movement and mobility after surgery in older participants with fragility neck of femur fracture.

Design

Prospective single centre, randomised controlled pragmatic trial.

Setting

Secondary care, acute NHS Trust, UK.

Participants

Participants admitted with a history and examination suggesting fractured neck of femur.

Intervention

Immediate continuous femoral nerve block via catheter or standard analgesia.

Results

One hundred and forty one participants were recruited, with 23 excluded. No significant difference was detected between cumulative dynamic pain scores (standard care (n = 56) vs 4

intervention (n = 55) 20 (IQR 15-24) vs 20 (15-23) p=0.51) or cumulated ambulation scores (standard care vs intervention 6 (5-9) vs 7 (5-10) p=0.76). There were no statistically different differences in secondary outcomes except cumulative pain at rest: 5 (0.5-6.5) in the standard care group and 2 (0-5) in the intervention group (p=0.043).

Conclusions

Early application of continuous femoral nerve block compared with standard systemic analgesia did not result in improved dynamic pain scores or superior post-operative ambulation. This technique may provide superior pain relief at rest. Continuous femoral nerve block did not delay initial control of pain, or mobilisation after surgery.

Item Type:	Article
Keywords:	Femoral nerve block; Hip fracture; Regional anaesthesia; Pain control; Older people
Schools/Departments:	University of Nottingham, UK > Faculty of Medicine and Health Sciences University of Nottingham, UK > Faculty of Medicine and Health Sciences > School of Medicine > Division of Clinical Neuroscience
Identification Number:	10.1136/bmjopen-2017-019650
Related URLs:	URL URL Type https://creativecommons.org/licenses/by-nc/4.0/ UNSPECIFIED
Depositing User:	Eprints, Support
Date Deposited:	05 Mar 2018 09:01
Last Modified:	15 Apr 2018 22:18
URI:	https://eprints.nottingham.ac.uk/id/eprint/50162

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